electron transport

Question 1

The electron transport/oxidative phosphorylation pathway consists of a chain of enzymes and other molecules that results in a high yield
of _______ molecules (metabolic energy)

Answer 1

ATP

Question 2

In eukaryotic cells, these processes take place in ___________,
as does the TCA cycle

Answer 2

mitochondria

Question 3

The electron transport/oxidative phosphorylation proteins are
integral membrane proteins of the inner mitochondrial
______________.

Answer 3

membrane

Question 4

During electron transport, a ________ gradient is established across the
inner mitochondrial membrane.

Answer 4

proton

Question 5

During ___________, the movement of protons through
the ATP synthase enzyme in the inner mitochondrial membrane
leads to the synthesis of ATP molecules.

Answer 5

oxidative phosphorylation

Question 6

T or F: The TCA cycle (citric acid cycle) and electron transport/oxidative phosphorylation
pathway are linked by the protons and electrons bound to ATP

Answer 6

FALSE

Question 7

________is a carrier for protons and electrons in
electron transport:
NADH → NAD+ + H+ + 2e -

Answer 7

NADH

Question 8

Protons and electrons are both required in the
reaction involving _________:
½ O2 + 2H+ + 2e - → H2 O

Answer 8

oxygen

Question 9

NAD+ and NADH have central roles in energy generation in the ____________.

Answer 9

mitochondria

Question 10

T or F: The mitochondria is the size of an E. Coli bacteria

Answer 10

True

Question 11

the inner membrane of the mitochondria is home to the 4 _____________ __________.

Answer 11

Protein complexes

Question 12

Human mitochondrial DNA encode 13 proteins, 22 tRNAs and _ rRNAs.

Answer 12

2

Question 13

In the electron transport chain, electrons and protons are transferred between the protein complexes by
coenzyme Q (UQ) and cytochrome c (cytc). This leads to the transport of protons across the ______
mitochondrial membrane by Complexes I, III, and IV to generate a proton ________ across the membrane.

Answer 13

Inner and gradient

Question 14

Protons are transported from the mitochondrial
matrix to the intermembrane space by
Complexes ________, _______and ________.

Answer 14

I, III, and IV

Question 15

The transport of electrons and protons between
the protein complexes is brought about by:

Answer 15

a) Coenzyme Q (CoQ or UQ [ubiquinone])
(b) Cytochrome c (Cytc)

Question 16

The ETC chain happens between the _________space and the ________ of the mitochondria.

Answer 16

intermembrane and matrix

Question 17

For example, Complex I has the enzyme name NADH coenzyme Q
reductase, and is also known as _____________ because it contains
the coenzyme flavin mononucleotide (FMN).

Answer 17

flavoprotein 1

Question 18

As another example, ________ is also known as succinate-
coenzyme Q reductase and as flavoprotein 2, because it binds the
coenzyme flavin adenine dinucleotide (FAD).

Answer 18

Complex II

Question 19

FMN and FAD are derivatives of _________ (vitamin B2 )

Answer 19

riboflavin

Question 20

what is the most important protein in the three pathways to making atp?

Answer 20

ATP Synthase

Question 21

The __ unit catalyzes ATP synthesis.

Answer 21

F1

Question 22

The F0 unit forms a ____________ pore or channel through which protons move to drive ATP synthesis.

Answer 22

transmembrane

Question 23

complexes a, b and c are part of which integral membrane protein complex?

Answer 23

F0

Question 24

The electron transport/oxidative phosphorylation enzymes produce a proton gradient that
results in ____________ _________ in ATP synthase and leads to ATP synthesis.

Answer 24

conformational changes

Question 25

There are specific channels in the mitochondrial membrane that allow only NADH to pass through.

Answer 25

FALSE, it is liked to the oxloacetate to produce malate and is transported across the membrane

Question 26

The NADH produced by glycolysis in the cytosol cannot pass through the inner mitochondrial
membrane.

Answer 26

TRUE

Question 27

herefore, the H+ of NADH, and free H+ , are linked to oxaloacetate in the cytosol to
produce _______, which is readily transported into the mitochondrial matrix.

Answer 27

malate

Question 28

H + are then added back to NAD+ to regenerate NADH. This effectively transfers NADH from the _________ into the _______.

Answer 28

Cytosol into the matrix

Question 29

complex I is also called…?

Answer 29

NADH-coenzyme Q reductase

Question 30

complex II is also called…?

Answer 30

succinate-coenzyme Q reductase

Question 31

complex III is also called…?

Answer 31

Coenzyme Q-cytochrome c reductase

Question 32

complex IV is also called…?

Answer 32

cytochrome c oxidase

Question 33

Each of these large multisubunit complexes is a component of the __________ ___________membrane

Answer 33

inner mitochondrial

Question 34

Cytochrome c is water soluable?

Answer 34

true