EM3 M4 Flashcards
(85 cards)
hypertensive emergency aka aka
define
9 examples
hypertensive emergency aka malignant hypertension aka hypertensive crisis
defined as hypertension with end-organ damage
eg hypertensive encephalopathy, intracerebral hemorrhage, hypertensive retinopathy, heart failure and pulmonary edema, acute coronary syndrome, acute renal failure, aortic dissection, eclampsia
5 ocular signs of hypertension
5 ocular signs of hypertension
- arterio-venous nicking
- linear or flame-shaped hemorrhages and cotton wool patches (infarction of nerve layer from arteriolar occlusion)
- copper or silver arteriole discoloration from sclerotic changes
- lipid (hard) exudates from htn permeability changes
- optic disc edema from infarction of optic disk is hallmark of malignant hypertension
treat htn in aortic dissection
sublingual nifedipine?
propanolol (bb) and nitroprusside (vasodilator)
with SBP goal 120, or if htn emergency goal 20-25% reduction in 30-60 minutes, or if htn urgency goal reduce over hours to days
NOT sublingual nifedipine – dangerous overshoot BP reduction
selectiveness of labetalol propranolol metoprolol atenolol esmolol
which has elimination half life of minutes
labetolol - nonselective beta also alpha blocking
propanolol - nonselective beta block
metoprolol atenolol esmolol - beta 1 selective
esmolol has elimination half-life of minutes
treat htn from pheochromocytoma with ___ not ___
why
alternatives
treat htn from pheochromocytoma with Alpha blockade NOT beta blockade… contraindicated till after alpha blockade to avoid paradoxical increase in blood pressure due to antagonism of skeletal muscle vasodilation
nitroprusside CCBs ACEIs alternatives to alpha blockade
what is the goal for malignant htn after reducing SBP 25-30% in the first hour
SBP reduction 25-30% in first 30-60min
then 160/100 in 2-6 hours of treatment
preferred initial agent for treating hypertensive emergency
esmolol IV
100-500 mic/kg load
TF
shingles can present after mechanical trauma
treat in ED
T
shingles can present after mechanical trauma
discharge home with analgesics and acyclovir
etiology of stasis dermatitis
impaired oxygen delivery to skin and subcutaneous tissue… gradual and chronic
Smallpox incubation period __ weeks.
__ day prodromal phase characterized by ____.
temperature subsides over __ days.
____ precedes skin rash by a day.
Skin rash begins as ____ which become ____ then ____ then ____ then ____ over the course of ____.
lesions occur first ____ then spread to ____.
Distribution is ___ and lesions are all at ____ stage of development.
Death from smallpox is from ____
Smallpox incubation period 1.5-2 weeks.
2-3 day prodromal phase characterized by fever headache backache.
temperature subsides over 2-3 days.
Enanthem over tongue mouth and oropharynx precedes skin rash by a day.
Skin rash begins as small reddish Macule which become Papules then Vesicles then Pustules then Umbilication and Crusting over the course of ~2 weeks.
lesions occur first on Face and Extremities then spread to Cover the Body.
Distribution is Peripheral and Centrifugal and lesions are all at The Same stage of development.
Death from smallpox is from Toxemia from immune complex deposition and HypOtension.
Diagnosis:
incubation period 1.5-2 weeks.
2-3 day prodromal phase characterized by fever headache backache.
temperature subsides over 2-3 days.
Enanthem over tongue mouth and oropharynx precedes skin rash by a day.
Skin rash begins as small reddish Macule which become Papules then Vesicles then Pustules then Umbilication and Crusting over the course of ~2 weeks.
lesions occur first on Face and Extremities then spread to Cover the Body.
Distribution is Peripheral and Centrifugal and lesions are all at The Same stage of development.
Death is from Toxemia from immune complex deposition and HypOtension.
Smallpox
incubation period 1.5-2 weeks.
2-3 day prodromal phase characterized by fever headache backache.
temperature subsides over 2-3 days.
Enanthem over tongue mouth and oropharynx precedes skin rash by a day.
Skin rash begins as small reddish Macule which become Papules then Vesicles then Pustules then Umbilication and Crusting over the course of ~2 weeks.
lesions occur first on Face and Extremities then spread to Cover the Body.
Distribution is Peripheral and Centrifugal and lesions are all at The Same stage of development.
Death from smallpox is from Toxemia from immune complex deposition and HypOtension.
Erythema Multiforme exists on a spectrum with ___ and ___ and causes include…. such as…
Erythema Multiform/Stevens-Johnson/Toxic Epidermal Necrolysis exist on a spectrum
causes include drugs (sulfa antibiotics, penicillins, barbiturates), viral or mycoplasma infections, recent immunization
treat cellulitis vs recurrent cellulitis in diabetic
cellulitis - cover GPCs staph and strep… penicillinase-resistant penicillins (dicloxacillin nafcillin oxacillin)… or 1st generation cephalosporins (cephalexin cefazolin)
recurrent cellulitis in diabetic- cover GPCs and GNRs… broader spectrum… Unsayn (Ampicillin-Sulbactam)
when (ages) is seborrheic dermatitis common vs uncommon
treat seborrheic dermititis
topical steroids?
common in infants and elderly
uncommon between infancy and puberty
treat with anti-dandruff shampoo
NOT steroids
what rash is associated with an anterior and posterior thorax Christmas-tree pattern distribution
pityriasis rosacea
is associated with an anterior and posterior thorax Christmas-tree pattern rash distribution
what color under Woods Lamp UV light? erythrasma tinea versicolor pseudomonas porphyria cutanea
what color under Woods Lamp UV light? erythrasma - red/pink tinea versicolor - green/yellow pseudomonas - yellow/green porphyria cutanea - urine orange/yellow
to achieve large differences in potency of topical steroid, is it more effective to switch agents or vary the dose of the same agent?
it is more effective to switch agents to achieve large differences in potency of topical steroid… changing dose does not affect potency much
how is potency of topical steroid measured
potency of topical steroid is measured by the ability to induce vasoconstriction
why are interrupted application schedules of topical steroid use preferred
because tachyphylaxis (vasoconstriction in response to corticosteroid use decreases over time), so on 2 weeks off 1 week preferred
____ steroids are to be avoided in pregnant women
Fluorinated steroids are to be avoided in pregnant women
is topical Hydrocortisone preferred for thick or thin skin?
topical Hydrocortisone preferred for Thin skin… relatively low potency steroid
Treat diffuse pruritus of most of the body
First gen second gen antihistamine?
Topical PO IV?
Anything else?
First gen ok second gen antihistamine lower dose frequency requirement and less sedation but more costly
PO ok can also do IV if necessary, not topical becuase can overdose when spreading over large area hard to estimate total dosing
Baths and soaks too
____ are white in color, greasy in texture and can be applied to any body surface area. These characteristics make them the most versatile vehicle. ____ are for acute use only; chronic use leads to drying of the skin. ____ are composed of greases such as petroleum jelly with little water added. ____ can help lubricate skin lesions that are particularly dry. ____ are greaseless mixtures of propylene glycol with water and may or may not contain alcohol. ____ are drying and are best for exudative lesions such as poison ivy but will cause discomfort in denuded areas. ____ are used for dry scaly conditions.
Creams are white in color, greasy in texture and can be applied to any body surface area. These characteristics make them the most versatile vehicle. Creams are for acute use only; chronic use leads to drying of the skin. Ointments are composed of greases such as petroleum jelly with little water added. Ointments can help lubricate skin lesions that are particularly dry. Gels are greaseless mixtures of propylene glycol with water and may or may not contain alcohol. Alcohol-containing gels are drying and are best for exudative lesions such as poison ivy but will cause discomfort in denuded areas. Alcohol-free gels are used for dry scaly conditions.
Tzanck preparation can identify the ____ but cannot distinguish among them
Tzanck preparation can identify the herpes viruses but cannot distinguish among them