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Flashcards in Embro Deck (31):
1

Truncus arteriosus gives rise to

Ascending aorta
Pulmonary trunk

2

Bulbous cordis gives rise to

Outflow tracts of both ventricles(smooth walled)

3

Primitive atria gives rise to

Trabeculated part of both atria

4

Primitive ventricles gives rise to

Trabeculated part of both ventricles

5

Primitive pulmonary vein gives rise to

Outflow tract of left atria( smooth walled)

6

Right horn of sinus venousus?

Smooth walled part of R/atria

7

Left horn of s venousus?

Coronary sinus

8

R/ common and anterior Cardinal veins

SVC

9

Heart starts working when

4 th week of gestation

10

First organ to function

Heart

11

Cardiac looping
-begins when
- what
-defect in what can cause abnormalities /eg

-week 4
-cardiac tube rotates to get a left right polarity
-R/L Dyenin defect dextrocardia
-eg Kartegeners syndrom

12

Formation of interatrial septum

Ostium primum
Septum primum grows toward endocardial cushions
Closes os primum
Defect in septum primum-os secondum
Septum secondum closes most part of os secondum
Opening left-for amen ovale
Remaining sept primium-valve of foreman ovale

13

Closing of formen ovale
-how
-when

Fusion of septum primum and secondum
At birth with increase LA pressure

14

Patent foremen ovale
-what
-treatment
-complication

Failure to fuse two septa
Usually left untreated
Paradoxical emboli

15

Interventricular septum formation

Muscular septum forms
Aorticopulmonary septim rotates and form membranous septum
Both fuse

16

VSD occurs where commonly

In membranous part

17

Outflow tract formation

TA rotates
Endocardial cells and neural crest cells migrate
Form bulbar and truncal cushions
Fuse spirally and form aorticopulmonary septum

18

Endocardial cushions involve in what structures

Separation of A and V
Atrial septum
Memb ventricular sept

19

Valve development

A/P-endocardial cushion of outflow tract
M/T-endo cushions of AV canal

20

Fetal erythropoesis structures involved with time

Y🍄oung L🍄iver S🍄ynthasises B🍄lood
Yolk sac-3w-8w
Liver-10w -birth
Spleen-6w -28w
Bone marrow-18w-adult

21

Embryonic globins
Fetal HB
Adult HB

Delta €
Alpha2 gamma2
Alpha2 beta 2

22

Difference bw adult and fetal HB

Fetal HB high affinity to O2 as it has low affinity to 2,3BPG
facilitates O2 uptake from maternal HB

23

Fetal circulatotion
-umb vein num
-umb atery num
-O2 saturation in vein and artery
-PO2 in umb vein

1 vein
2 arteries
80% O2 in vein less in artery
30mmhg

24

Important shunts in fetal circulation

Umb v to ductus venousus to IVC(by pass hepatic cir)
IVC to RA to f.ovale to LA/LV to asce aorta
SVC to RV to pull trunk to PDA to desc aorta

25

How are the shunts close at birth

Breathing increase O2 pp in plum cir
Reduce pulm cir resist
Blood goes to pulm cir
High pressure in LA
Closes f ovale

Increase O2 and reduce prostaglandin closes ductus arteriosus

26

What keeps DA open and close

Close Indomethacin
Open by Prostaglandins(P-Patent)PE1 PE2

27

Post natal derivatives
Allontios
D arteriosus
D venousus
F ovale
Notochord
Umb arteries
Umb vein

MediaN umb lig
Lig ateriosum
Lig venosum
Fossa ovalis
Nucleus pulposus
MediaL umb lig
Ligamentum teres hepatic in falciform ligament

28

Coronary cir main vessels and supply what

LCA
1.LAD-ant LV
Any 2/3 interventr sept
Anterolateral papillary musc

2.LCX-Lateral and post walls of LV
Anterolateral papillary musc

RCA
1.R/marginal-ant RV
2.PDA-post ventricles
Post 1/3 of IV sept
Posterio medial papillary muscle

29

SA and AV nodes supplied by
Block in those arteries can cause

RCA
bradycardia and heart blocks

30

What are R/L/Codominant circulation

R domi-RCA gives PDA-85%
L domi-LCA 8%
Codominant-both -7%

31

CAD mostly affect which artery
Coro blood flow peaks when
Most posterior part of heart and its engagement causes what

LAD
early diastole
LA-dysphasia press oesophagus
Horseness press LRL nerve branch of vagus