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Anat unit 2 > Embryo- Development of the Genital System > Flashcards

Embryo- Development of the Genital System Flashcards

(68 cards)

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1
Q

genital system develops from what mesoderm?

A

intermediate

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2
Q

lateral body folding in embryo occurs

A

week 4

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3
Q

urogenital ridge is (space)

A

bilateral

retroperitoneal

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4
Q

urogenital ridge portions

A 
nephrogenic cord (lateral)
gonadal ridge (medial)
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5
Q

nephrogenic cord produces

A

urinary structures

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6
Q

gonadal ridge produces

A

genital structures

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7
Q

indifferent stage of sexual development

A

weeks 1-6

both sets of genital ducts present

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8
Q

female genital ducts

A

paramesonephric (mullerian) duct

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9
Q

male genital duct

A

mesonephric duct (wolffian) duct

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10
Q

gonadal ridge formed when

A

week 5

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11
Q

how is gonadal ridge formed?

A

intermediate mesoderm thickens bilaterally

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12
Q

gonadal (cortical) cords formed when

A

gonadal cord cells sink into underlying mesenchyme to envelop PGCs

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13
Q

mesothelial cells of gonadal ridge that develop when mesothelium lining of gonadal ridge thickens

A

gonadal cord cells

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14
Q

hormones necessary for development of testes

A

SRY - sex determining region of Y chromosome

TDF - testes determining factor

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15
Q

Leydig cells develop from

A

gonadal ridge mesenchyme

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16
Q

Leydig cells produce

A

testosterone

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17
Q

Gonadal cords separate and extend into medulla of testes and envelop PGCs to form

A

seminiferous tubules + rete testes

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18
Q

sertoli cells develop from

A

gonadal cord cells

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19
Q

cord cells form primitive gonadal (cortical) cords when?

A

week 6

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20
Q

remnants of mullerian duct in male

A

prostatic utricle

appendix testes

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21
Q

mesonephric duct forms

A

vas deferens

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22
Q

superior mesonephric duct forms

A

epididymis

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23
Q

mesonephric tubule forms

A

efferent ductules

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24
Q

caudal mesonephric duct forms

A

seminal vesicles + ejaculatory duct

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25
ejaculatory ducts open into
prostatic urethra
26
mesonephric duct derivatives
epididymis vas deferens ejaculatory duct seminal vesicle
27
gonadal cord derivatives
seminiferous tubules | rete testes
28
endodermal outgrowths of urogenital sinus (male)
bulbourethral gland | prostate gland
29
Mullerian Inhibiting Hormone (MIH) produced by
sertoli cells (which are dev. from gonadal cord cells)
30
MIH causes
regression of mullerian duct (female)
31
when does descent of testes occur?
weeks 26-32 | begins week 26 - both in scrotum by 32
32
gubernaculum story
ligament extends from gonad to labioscrotal swelling -> shortens and pulls down testes, vas deferens, testicular vessels thru abdominal wall -> scrotal sac
33
layers of spermatic cord derived from
anterior abdominal muscles + fascia
34
ext. spermatic fascia from
ext. oblique muscle
35
cremasteric fascia from
int. oblique muscle
36
internal spermatic fascia
transversalis fascia
37
patent processus vaginalis
congenital inguinal hernia
38
development of fluid filled cysts
hydrocele of testes/spermatic cord
39
failure of testes to descend
cryptorchidism
40
what must be absent for ovary development to occur
SRY and TDF
41
stromal cells of ovary develop from
mesenchyme of gonadal ridge
42
follicular cells of ovaries develop from
gonadal cord cells
43
how are ovarian follicles formed?
follicular cells formed from gonadal cord cells surround PGCs and form ovarian follicles
44
follicular cells are formed by
cortical cords break up, cord cells develop into flat follicular cells
45
follicular cells surround
oogonium
46
oogonia turn to primary oocytes when
months 3-7
47
primordial follicle made up of
primary oocyte + follicle cell capsule
48
low testosterone causes
mesonephric duct regression
49
no MIH causes
continued growth of mullerian duct (paramesonephric)
50
mesonephric duct remnants
epoophoron paraophoron Gartner's duct cyst
51
mullerian duct forms what structures
superior vagina, uterus, uterine tubes
52
cranial ends of mullerian duct form
uterine tubes
53
caudal ends of mullerian ducts fuse to form
uterovaginal primordium
54
uterovaginal primordium forms
uterus and superior vagina
55
sinovaginal bulbs formed when
endodermal outgrowths formed when uterovaginal primordium comes into contact with dorsal wall of urogenital sinus
56
vaginal plate formation
sinovaginal bulbs separate from sinus + fuse with uterovaginal primordium
57
vaginal canal formation
central endodermal cells of vaginal plate degenerate
58
endodermal outgrowths of urogenital sinus
greater vestibular glands urethral glands paraurethral glands
59
female derivatives of gubernaculum
ovarian ligament | round ligament of uterus
60
peritoneal fold becomes
broad ligament
61
urogenital sinus becomes future
bladder
62
clitoris
genital tubercle
63
labia majora
labioscrotal swellings
64
labia minora
urethral folds
65
glans penis
genital tubercle
66
scrotum
labioscrotal swelling fuse at midline
67
penile shaft
urethral folds fold ventral + fuse
68
male external genitalia differentiation induced by
testosterone (leydig cells)

Anat unit 2 (9 decks)

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