Embryology Flashcards

1
Q

How many hours after fertilisation does eggs split into two blastomeres? How many cells after 3 more divisions? Known as what?

A

30 hours
16 cells
Morula

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2
Q

Within what week do the cells of the morula reorganise to form the blastocyst cavity?From then, known as what? Two cell types?

A

1st week
Blastocyst
Outer mass= trophoblast– endometrium for implantation
Inner mass= embryo blast

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3
Q

During what week does the trophoblast divide into the synctiotrophoblast and cytotrophoblast? The embryo blast divides into what? Known as what?

A

2nd week
Epiblast and hypoblast
Bilaminar disc

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4
Q

Amniotic cavity forms within what?

A

The epiblast

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5
Q

What happens in 1st week of embryonic period? 2nd week? 3rd week? 4th week? 5th- end of 8th week? End of 8th week?

A

Fertilisation and blastocyst formation- F= first
Implantation and bilaminar disc formation (2= bi)
Embryo development and trilaminar disc forms
Folding of embryo (F=4th=folding)
Development of all organs
All organs have developed and embryo looks like an adult- called a foetus

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6
Q

Which layer becomes continuous with the uterus? Maternal blood vessels known as what? Invades spaces in synctiotrophoblast known as what?

A

Synctiotrophoblast
Sinusoids
Lacunae

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7
Q

What occurs during gastrulation (3rd week)? Orchestrated by what? What is this? What lies within this and this?

A

Bilaminar disc forms 3 germ cell layers
Primitive streak
Groove in midline of epiblast
Primitive node at cranial end- within this= primitive pit.

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8
Q

Cells of epiblast break off and migrate towards primitive pit to form what 3 layers? They are each formed by what?

A

Endoderm, mesoderm and ectoderm
Endo= epiblast cells migrate through primitive pit and displace hypoblast cells
Meso= epiblast cells migrate through primitive pit and lie between epiblast and newly formed endoderm
Ecto= epiblast cells that remain in position

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9
Q

What structures derive from the endoderm?

A

Epithelial lining of GI and resp tract, lining of urethra, bladder and reproductive system, liver and pancreas

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10
Q

What structures derive from mesoderm?

A

Notochord, MSK system, muscular layer of stomach, intestine etc., circ system

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11
Q

What structures derive from ectoderm?

A

Epidermis of skin, cornea and lens of eye, CNS and PNS

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12
Q

What are the 3 mesoderm parts? What does each form?

A

Paraxial plate, intermediate plate and lateral plate
Paraxial–> somites–> a) Myotome- muscle tissue, b) sclerotome- cartilage and bone, c) dermatome- dermis of the skin
Intermediate—> kidneys, gonads and respective duct systems
Lateral–> 1) somatic- body wall, 2) splanchnic–> circ system, connective tissue for glands, muscle, connective tissue and peritoneal components of way of the gut

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13
Q

Somites develop in what direction? 1st pair on what day? At rate of how many pairs a day until 42-44 pairs formed?

A

Cephalocaudal direction- head to tail (paired segments on each side of notochord)
Day 20= 3 pairs per day until 42-44 pairs are formed

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14
Q

Where is oropharyngeal membrane what does it consist of? Where is cloacal membrane and what does it consist of?

A

At cranial end= small region of tightly adherent ectoderm and endoderm cells–> oral cavity
No mesoderm between ecto and endoderm
Caudal end- tightly adherent ectoderm and endoderm cells- no intervening mesoderm

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15
Q

What does cranial area contain? Where does cranial flexion bring these things?

A

Buccopharyngeal membrane, cardiogenic area and septum transversum–> ventrally–> ventral surface of future face, neck and chest
Heart into thoracic position and septum transversum–> diaphragm

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16
Q

What does caudal flexion do to cloacal membrane? What does lateral folding result in?

A

Brings it onto the ventral surface of the embryo

Incorporation of portion of yolk sac into embryo to form primitive gut, body cavities

17
Q

What is primitive gut and what is it divided into? What is midgut connected to yolk sac by? Where does foregut extend from and to? Midgut? Hindgut?

A

Blind-ended tube–> foregut, midgut and hindgut
Vitelline duct
Oropharyngeal membrane–> liver bud
Liver bud–> end of right 2/3 transverse colon
Beginning left 1/3 of transverse colon–> cloacal membrane