Emed Invx & Mx Flashcards

(77 cards)

1
Q

Tachydysrhythmia; unstable patient

A
  1. Monitor in high acuity area with continuous cardiac and vitals
    monitoring.
  2. Assess responsiveness and pulse. If pulseless, begin CPR.
  3. ABCs with IV access for drugs.
  4. Stable vs Unstable (signs of shock such as hypotension).
  5. Assess for clinical features of severe dysrhythmia. (Chest pain,
    diaphoresis, dyspnoea, AMS, cold clammy skin).
  6. 12-lead ECG for evaluation. (Wide vs Narrow complex tachycardia)

Unstable
1. consent sync cardioversion
2. sedation & analgesia
3. O2
4. 100J for Wide complex tachy; 50J for narrow complex tachy
5. reassess

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2
Q

Mx of Atrial flutter & A fib

A

Check reversible causes:
Infection, AMI, alcohol,
thyrotoxicosis, acute PE, myocarditis.

CHADVASCc score: >2 anticoagulation; HASBLED score risk of bleeding

Rate control:
assess presence of HF;
no HF:
CCBs:
avoid in hypotension or WPW + AF:
1. Dilt 0.25mg/kg IV over 2 min; 15min wait; repeat slow bolus 0.35mg/kg
2. Verapamil 5-10mg IV slow bolus, continuous infusion.

BB: use in thyrotoxicosis
1. Esmolol 500ug/kg IV over 1 minute, infusion 50-200ug/kg/min
2. Metoprolol 2.5-5mg IV slow bolus every 5 minutes up to 15mg
3. Propranolol 1mg IV over 1-minute repeat at 2–3-minute intervals up to 3 doses

AF with HF: Digoxin: 0.25-0.5mg IV;
avoid in WPW + AF

Use in AF + WPW
Procainamide 10-17mg/kg IV at a rate of 20-50mg/min loading dose. Stop if arrhythmia suppressed, hypotension, QRS >50% widened

HFpEF:
CCB or BB

HFrEF:
Amiodarone 150mg IV over 30 minutes then 1mg/min for 6 hours. Avoid in WPW with AF and
ABCD HF drugs.

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3
Q

SVT mx

A
  1. Vagal maneuvre:
    Valsava; carotid sinus massage
  2. pharm:
    6,12,18mg IV adenosine rapid bolus 20ml saline flush; three-way plug ; lifting the IV arm 1-2 miutes in between.

inform impedening doom; transient asystole

Dilt: 0.25mg/kg IV 2min;
15 minutes, repeat slow bolus 0.35mg/kg.
Verapamil: 5-10mg IV slow bolus then continuous infusion

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4
Q

Monomorphic VT

A

Pulseless ACLS

stable:
1. IV amiodarone 150mg over 15 mins repeated once, 1mg/min infusion for 6 hours. Up to 2.2g
2. IV lid ocaine 1-1.5mg/kg IV infusion 10mg/min. Repeated once
at half the dose, if necessary, after 5 minutes. Up to 3mg/kg

If pharmacology fails, proceed to synchronized cardioversion

Monitor for VFib

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5
Q

TdP mx

A
  1. Correct electrolyte abnormalities causing prolonged QT especially
    hypoMg and hypoK, hypoCa
  2. IV MgSO4 1-2g over 60-90s then 1-2g/h infusion

Halt any drugs which may cause QT prolongation. (Eg. Procainamide, amiodarone, sotalol, TCAs, macrolides.)

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6
Q

HyperK Mx

A

ABCs; set 2 large bore IV cannulas.
a. Check potassium levels and ensure it is not pseudohyperkalemia.

  1. ECG assess
  2. Stabilize the cardiac membrane.
    a. 10% 10ml Calcium gluconate over 10 minutes.
  3. Shift potassium intracellularly.
    a. IV Dextrose 50% 40ml over 10 minutes.
    b. IV 10 units regular insulin. (Or 6 units in CKD)
    c. Sodium bicarbonate if cardiac arrest or peri arrest.
    d. Nebulised salbutamol 5mg in 3ml saline over 10 minutes.
  4. Remove potassium from body.
    a. PO Resonium A 15g 4-6 hourly
    b. PO Zirconium cyclosilicate (Lokelma) 10g TDS up to 2
    days, if available in the hospital.
    c. Haemodialysis after renal medicine consultation
  5. Prevent further increase in potassium.
    a. Review all medications (Use of span K, ACE-Is, Betablockers) and diet (excessive banana consumption)
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7
Q

polymorphic VT

A
  1. Amiodarone for chemical cardioversion.
  2. Look for evidence of ischemia.
  3. Look out for QTc>500ms or ‘R on T’ phenomenon suggesting
    impending TdP development.
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8
Q

Bradyrhythms acute mx

A
  1. ABCs and establish IV access.
  2. Obtain FBC, RP, Cardiac enzymes.
  3. Attach continuous ECG monitoring and defibrillation pads.
  4. Assess vitals and take a history and physical exam.
    a. Assess for serious signs and symptoms of bradycardia
    (CHAPS)
    i. Chest pain or breathlessness
    ii. Hypotension
    iii. AMS
    iv. Pulmonary edema
    v. Shock
    b. IF present then proceed with intervention
    c. IF no serious signs and symptoms then type II 2nd degree
    HB and complete HB are the ones that need to be closely
    monitored and prepared for pacing as they may
    deteriorate.
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9
Q

mx of bradyrhythms

A

1st line:
IV Atropine 0.6mg every 3-5 minutes up to 2.4mg
a. Target is to resolve symptoms and 60-70 BPM.
CI post heart transplant - paradoxical bradycardia; consider theophylline or aminophylline

2nd line
1. IV Dopamine 5-20ug/kg/min infusion
2. IV adrenaline 2-10ug/min infusion

BB or CCB overdose:
IV glucagon + Ca gluconate OR HDIT

3rd line
Transcut pacing
sedation analgesia
60-70bpm
pacer ON ; electrical capture

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10
Q

STEMI equivalents + requiring PCI

A

Hyperacute T waves
Posterior MI
L MCA Occlusionn
De winter T waves

NSTEMI + VT/VF + cardiogenic shock
Persistent cardiac ischemia despite medical therapy

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11
Q

DW T waves & underlying cause

A

ST D; V1-6; J point up sloping
tall symmetrical T waves
no ST elevation

acute occlusion of Prox LAD

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12
Q

Left Main CA occlusion features

A

ST D; >1mm 6 leads; esp inferior leads
Max ST dep in I,II, v4-6
aVR STE reciprocal elevation – dx from prox LAD

PCI

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13
Q

Wellens syndrome

A

angina;
v2-v4 LAD T wave inversion
LAD critical stenosis
high risk of anterior AMI

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14
Q

Brugada; ECG findings; syndrome diagonosis

A

inherited dz
RBBB + ST elevations V1-3
ST segment - convex or coved
J pt elevation

no ST depression
prolonged PR interval

Syndrome
documented VT or VF
fmhx sudden cadiac death <45
no struc heart disease
syncope of unknown

treat implantable defib

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15
Q

ST depression ddx

A

Ischemia
posterior STEMI (inferoposterior or isolated posterior)
LMCA occlusion
DW T wave - LAD occlusion
Severe hypoK

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16
Q

ACS acute mx

A
  1. ABCs IV
    FBC, RP, trops (UA or STEMINSTEMI)
  2. hx
  3. ECG; hypocount, CXR
  4. DAPT: PO aspirin 300 + 180mgtica/600clopidogrel (low risk NSTEMI)
  5. SL GTN + nitroderm 5mg;
    persistent pain IV GTN 5-10ug/min
    CI: RV infarct (inferior STEMI),
    severe AS, PDEs (erectile)

a. IV fentanyl pain relief

  1. Cath lab activation
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17
Q

Acute HF mx

A

ADHF; cardiogenic APO; cardiogenic shock; hypertensive AHF; high output HF; isolated RHF

ABC IV;
FBC,RP,T
ECG

Upright
NIV CPAP
CXR
POCUS - EF, B lines on US - interstitial edema
US Of IVC

Pharm:
lower preload & afterload
GTN
2nd line: ACEi (E, Cpril)
3rd line: Diuretics (f)

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18
Q

RV infarct mx

A

no GTN
IV fluid challenge 100-200ml;5-10min
inotropic support

avoid morphine - increased mortality
DAPT A300, T180mg
PCI

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19
Q

HTN emergency mx

A

confirm HTN
ABCs, IV, clsely monitor
ECG, Dipstick (proteinuria, hematuria), UPT
FBC, RP, Trops, LFT (PreE)
CXR (widened mediastinum), CT brain
monitor, ECG SpO2, vitals q5-10

Ischemic stroke
HTN Enceph, APO, AMI, AKI, AD, PreE

IV labetolol, prop, esm, GTN, Nitroprusside, hydralazine, enealpril

Admit ICU Gen Med

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20
Q

A dissection mx;
common features

A

P1, vitals, ECG, SpO2
ABCs, IV
ECG (AMI), 2DE (widened AR>3cm)
FBC,RP, PT/PTT, GXM 4-6u, T
CXR, CT aortogram
infuse NS slowly
Observe chart: circulation, neruo

Aim: lower rate of B rise, mean BP, HR
SBP 100-120, UO>30ml/hr

IV labetalol 2-8mg/min rep 10min max 300mg 0.5-2mg/min, IV esm, IV prop
+ IV GTN 5-200ug/min, nicardipine, nitroprusside
IV morphine

Admit CT ICU

surgical repair be
Stanford A, B w complicatins, uncontrollable HTN, dissection

features:
Neuro (TIA, stroke, paraplegia)
BP diffeence >20mmHg between arms; LL BP<UL BP
Pain + AR murmur
ILEAD Pain
Inf MI
Ischemia - renal, spinal cord, mesenteric
GU cx - renal colic

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21
Q

AAA mx

A

ABCs, IV, BP 90-100
US >3cm AA diamter; FAST scan rupture
FBC, RP, PT/PTT, ABG, GXM 6u
CT aortogram CXR

p1; continuous monitoring ECG, SpO2, vitals

Surgery;
ruptured emergency repair
sx non ruptured – urgent
<5.5 asx - conservative

TEVAR stenting or open aneurysm

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22
Q

Pulm Embolism

A

signs; pleuritic CP, SOB, bloody sputum; syncope;
assesment
a. Sinus tachycardia.
b. Right heart strain pattern (T wave inversion V1-4,
R AxisD, S wave in I and aVL, P pulmonale,
c. RBBB
d. S1Q3T3

POCUS - D septum, RV enlargement; fixed dilated IVC

XR - normal; hamptons hump, fleischner sign, westermark
Ven compression US DVT
CTPA

PERC/Well’s – D dimer vs CTPA
Trop PBNP

Massive - arrest; pulseness; SBP<90
a. thrombolysis rTPA; thrombectomy embolectomy; IV heparin anticoag
Submassive - stable; RV injury Trops, PBNP>600, RV/LV>0.9
a. IV hep / SC LMWH
Low risk
DOACs

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23
Q

Asthma mx

A

Severity
Mild PEF>50, activity limitation, >90%, <120, phrases sentences
Moderate <50, rest, words, accessory muscle, <90& Sp,
Severe <25, unable to talk, mental status, cyanoiss, absent breath sound, bradycardia

RSI: drowsiness, confusion, silent chest, imminent respi collapse

Mild/moderate
a. 1ml (5mg) Salbutamol: 2ml Ipratropium bromide: 2ml normal saline nebulization
b. PO Prednisolone 0.5-1mg/kg up to 50mg or IV 100mg hydrocortisone.
c. O2 - SpO2 @ 93-95%

Unresponse:
i. MgSO4 1-2g/30 min
ii. rep neb
iii. admit EDTU

Severe
a. Salb 1:2:2, PO Pred, IV hydrocort
b. High flow O2
c. serial ABG

still in RD
ICU, CXR(PTX, infection, CCF)

Life threatening asthma
High flow O2;
Monitor ECG, SpO2, vitals every q5 minutes.
Serial ABGs
RSI

Well response
Discharge; TCU 48h
med compliance
ICS + 5-7 days oral corticosteroids

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24
Q

COPD

A

respiratory distress, hypercarbia, or imminent respiratory failure
a. continuous monitoring of vitals, SpO2, ECG.
CXR - pneumonia PTX
ABGs after 2 nebs
FBC, RP

Airway:
a. Supplemental low-flow oxygen @SpO2 at 88-92%.
b. Non-invasive ventilation (BiPAP)
c. judicious fluids

Bronchodilation
Sal, Ip, Pred, Hydrocort
No MgSO4
Abx - anthonisen criterai >2 (SOB, Sput vol, Purulent) ; signs of pneumonia or CXR consol
Aug, A Cythromycin, Cefuroxime, Levoflx

Disposition

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25
Pneumonia
ABCs, IV ECG, hypocount FBC, RP, blood culture (MRSA, PAE, spesis); lactate (severe CAP or sepsis) CXR, Lung US Risk strat CURB 65 (2 inpatient, 3 ICU) U7, R30, B(S90 D60), 65 Critical care or resus ECG, vitals, SpO2 Broad spec Abx w Institution abx 5-7days; melioidosis hospitalised: Aug + A, C+A, L severe CAP: A + A + C, C + A, M+ A PAE: PT, C, A+V+A
26
DKA & HHS
Dx criteria: CBG >14 pH<7.3, HCO3<15 BHB>3 or ketonuria 3+ HHS: CBG>33, rest same Serum Osm >320 ABCs IV O2; ECG, vitals, SpO2, hourly BG, ketones, K, acid base 4h FBC, RP, VBG, T, urinalysis, blood culture, ABG IV fluids - hartman or NS Assess K K+ <3.3: Withhold insulin, give IV KCL 20-40mmol/hr until >3.3 3.3-5.2: insulin with 20-30mmol K+ in each litre of IV fluid maintain 4-5mmol/L K+ >5.2: insulin and withhold K+ but check serum K+ every 4 hourly. Insulin DKA: bolus 0.1unit/kg IV soluble insulin HHS/DKA: 0.1unit/kg/hr continuous infusion reduce by 3-4mmol/L/hr. glucose levels drop <14mmol/L, halve the IV insulin rate to 0.05 units/kg/hr then start IV D5%.
27
6 life threatening CP causes
TAA PPE Myocard; pericarditis; pericardial effusion Pneumonia PE Zoster
28
SOB ddx and approach Important signs for each category Invx for SOB & findings
upper airway - cough, wheeze, fever, LL swelling; allergen exposure urticaria PPPP - PTX; Pleural effusion; pulmonary embolism (leg swelling, leg pain, RF, pregnancy); pneumonia Lung tissue; airway obstruction; pulmonary edema Creps, rhochi, reduced air entry Cardiac chest pain; PND, orthopnea, Dyspnea, low effort tolerance, leg swelling JV, edema, creps Anemia; DKA dehydration ECG, CBG; CXR; POCUS Lung - B profile, lung sliding, air bronchogram/shred sign/subpleural discontinuation Cardiac - EF, pericardial effusion, tamponade ABG
29
Giddiness/syncope/pre syncope
Vertigo/lightheadedness (syncope/presyncope) Non specific - ask for situation of giddiness presyncope - darkn vision; NV, weakness, dyspnea, axiety cardiac - Muscle, Rthm,Vlv, Fail Orthostatic - dehydration (NV diarrhea), baby metab; O2, gluc, uremia, anemia TRO - IHD, rthm; infection; bled; VBI/CVD Syncope Vasovagal - toilet Cardiac - MRVF; LVOO; RVOO; (AS, HCOM) (tamp, PE, p htn) Ostatic - dehydration (bleed ectopic, GI); autonomic DM or PD Neurogenic - TIA, SAH, subclavian steal Ddx seizure from syncope jerk + biting vs transient sloww post ictal confusion; rapid aura incontinence common vs seldom
30
toxidromes
31
LL swelling
Bilateral ; heart, kidney, liver/gi; vein/lymph; drugs; preg pre E traumatic Uni: #, rhabdo, contusion, hematoma; compartment syndrome atrumatic: eriseplas; cell; myositis; lymphangitis DVT, bakers; bone ca; OM; (LL pain - LL ischemia)
32
orthopedic LL swelling invx & compx
compartment syndrome ; tib fib #; humerus; voltage brun myogl; RF; K volk; limb fx ECG (myocard); dipstick RP, T; LFT;
33
Trauma steps
prep & triage - resources, people, blood AT MIST (age, time, mech, injuries, s&s (GCS, vitals), treat) rapid assessment XABCDE - mx life threatening injuries X- pressure;tourn;topical hemostat A +Cspine (assume if obtund) - question; (voice, stridor, FB,#, RD); OP/NP airway unless in BOS#; definitive airway/collar B - (Penetration; RD; paradox flail); TPTX,HTX a. palp - deviat & creps (TPTX ; emphysema) b. perc - reso dull (HTX PTX) c. breath sounds - PTX HTX C - hemorrhage; tamponade D- brain injury;spine injry E - temp - hypo - blankets; bair hugger; fluids Adjuncts - E FAST; XR; ECG; BG; catheter secondary SAMPLE head-toe 1. head, eyes, maxfacial 2. C spine 3. chest 4. abdopelvis 5. log roll - spine (step deform), perineum (DRE - tone, #, high r prostate urethral injury - CI cath; bleed GI) 6. Neuro - GCS, PEARL, 7. XR & CT
34
GCS score fast EVM
E - spont; sound; pressure; no V - orient; conf; words; sounds; no M - obey, Localise, flexion (norm), flexion (abn),extn, no
35
palpitations approach Causes of papitations
SODCRATES: a. character: continuous tachy; multiple prem contrac b. rate; rhythm assoc: cardiac - diaph; pain; SOB, postur dizzy; syncope thyroid; anemia meds; COPD/OSA mhx: young cardiac death; heart disease thyroid (heat, wt, eat, anxi) pheo (headache; diaph); hypogly drugs (caff; alcohol; salb) cardiac cause tachy (sinus or tachy) PAC or PVC (myocard scarring - ischemia; LVH; HCM); pulmonary (COPD OSA); drugs non cardiac - caffeine; glucose; alcohol; anemia; pheochrom
36
# suggestive ecg features of structural abnormalities; conditions Conditions predisposing to tachys ECG features
ongoing palpitations - ECG - PVCs/PACs resolved palpitations - T or ST - ischemia P mitrale pulmonale - large atrium - A fib HCM - L atrial H, LVH, lateral lead deep Q (SVT, AF, VT) WPW - sinus rhythm + PR <3square 120ms; delta wave (rise of QRS); QRS >110 brugada - 3 ecg characteristics a. j pt elevation v1-3; cove ST; neg T b. hx - syncope, SCD 45, VF V coved or saddleback prolonged QTc; >450ms, SCD, VF, TdP; QTC ? 1/2 RR int congenital; acquired - a. hypoKCM b. Drugs - 1,3 arrhythmics; Psych, Mac, flox c. ischemia
37
Management of anaphylactic & septic shock
anaphylaxis: IM adrenaline + antihistamines (Diphen 25-50 Prom 25-50, Chlor) Cimetidine; ranitidien decontaminate - allergen Hydrocort 200mg IV glucagon sepsis SOFA>2; >22, BP<100 shock, lactate>2 fluid resusc; MAP>65 requires vasopressors ECG, hypocount, ABCs IV FBC, culutre, RP, LFT, lact; abg, urine sepsis bundle: 3h lact, culture,, abx, 30ml/kg crystalloid for hypotension/lact>4 6h: MAP<65; vasodilators CXR and ARDs Vasop: NA 0.1ug/kg/min; dop 5 adrenaline GS consult for source control transfer ICU
38
hypoCa & hyperCa sx & mx
hypoCa: corrected Ca - hypoalb affects Ca total measured; ionised ca is unaffected cramps, tetanus, neuropathies; SOB, confusion; Chv=cheek; trosseau 1. ECG (prolonged QT, dysrhythmias), hypocount. 2. mild - Oral calcium replacement. 3. severe hypocalcemia, symptomatic, asymptomatic with <1.9mmol/L corrected calcium, severe hyperkalemia/magnesaemia, calcium channel blocker overdose and massive transfusion done. a. IV calcium gluconate 10ml over 10 minutes OR b. IV calcium chloride 10ml over 10 minutes (extravasation leading to tissue necrosis) hyper bones, stones, psychic moans, abdogroans asx - <3.0 -- advice water for stones Ca - 3-3.35 - Ca > 3.5; a. IV NS; IM/SC calcitonin; IV bisphosphonates Invx - PTH, D,
39
CHA2DS2VASC score
CCF, HTN, Age>75 (2), DM, Stroke TIA thromboemolism (2), vasc disease, 65-74, Sex female
40
mx of seizure
precip - meds, alcohol, sleep ABCE DEFG status - PE ECG CBG FBC, RP, electrolytes intracranial - neurosurg Neiss - 2g Cef IV BZD - PR diazepam 1. IV diazepam 0.15mg/kg max 10mg per dose, slow bolus at a rate of <5mg/min 2. IV lorazepam 4mg or 0.1mg/kg given over 1-2 minutes and repeated q 5 minutes up to 8mg. 3. IM midazolam 10mg AEDs IV phenytoin 20mg/kg up to 50mg/min IV valproic acid 40mg/kg at a rate of 5mg/kg/min IV levetiracetam (Keppra) 60mg/kg max 3000mg; 5mg/kg/min refrac Prop 1-2mg/kg bolus Midaz 0.2mg/kh continue AEDs RSI
41
list of POCTs
ABGs, CBG, UPTs, Dipstick, electrolytes ECG POCUS
42
Life threatening abdo pain + causes by region
perf PUD, IO AAAAD APpendix panc, ectopic, ischemic, perititonitis (SBP in cirrh, p dialysis) HPB sepsis AMI, lower lobe pneumon, basal PE, DKA RHC: asc cholangits, chole, biliary colic, abscess, divert, hepatitis,
43
TIA features & mx def of high risk purpose of ABCD2
a fugax highest risk stroke 24h, CBG, ECG AF FBC, RP Autoimmune markers CT brain MRI DWI CT angiogram US carotids high risk 300mg aspirin, 300 plavix 21 days admit neuro perm HTN 24h ABCD2 Defn of high risk: anticoag cardioembolic source recur TIA DWI infarct CT - acute/chronic ischemic lesion low risk - discharge followup 48h APT + lipid lowering agent
44
ABCD2 score
A >60 BP >140/90 Clinical Uni weakness; speech without weakess Duration >60, 10-59 DM 1 Low 3, mod 5, high 6,7
45
Stroke ddx etiologies of ischemic stroke key assessments
glyc, todd's paral, HTN encep; trauma, tumor, AD, migraine, Bell's last seen well 4.5 rTPA; endovasc thrombectomy within 24h CT brain NIHSS - severity - benefits of IV thrombo TOAST ischemic etiology - large vessel, cardioembolic, small vessel, others - AD, thrombophilia, embolic of unknown LvSvEcEuo O
46
mx ischemic stroke who shoudl get CT
last seen w; premorbid fx status, neuro deficits; NIHSS CBG, ECG NC CT - hemorrhagic CT: thrombolysis, endo thrombectomy, ICH (plt, clot, anticoag, BP, headache, vomitting), SAH (worst headache, meningism, LOC) early deterioration (severe cort stroke + hemipleg, eye deviation, aphasia, hemineglect) ischemic stroke ABCs IV O2 94-98% fluid resusc permissive HTN 220/120; lower 15% over 24h; rTPA 185/110 NBM- supine rTPA - 0.9mg/kg over 60%; 10% dose bokus monitor GCS Endovasc - 6-24h - risk of reperfusion NIHSS>6 ASPECTS>6 rankin scale <3 APT Aspirin 24h DAPT mild stroke NIHSS<6 3w, aspirin lifeling Severe stroke - no DAPT Disposition - Neurosurg intervention - HDU or ICU - hemorrhagic conversion, reperfusion injury
47
features of anterior vs posterior stroke
Ant 1. Hemiparesis 2. Unilateral sensory loss 3. Visual field deficit 4. Aphasia 5. Left-sided spatial neglect or hemi-inattention Post 1. Hemiparesis 2. Disconjugate gaze, diplopia 3. Homonymous hemianopia 4. Dysarthria + dysphagia 5. Alexia wo agraphia (inability to read without other signs of aphasia) 6. Vertigo 7. Vomiting D,AP, V2A2 H2
48
CT features of stroke additional assessment tools
NCCT Brain loss GW dx sulcal eff hyperdensity of dense MCA sign APSECTs socre for MCA stroke CT features w poor outcomes CT/MR angio - bleeds confm CT MRI perf - wake up stroke - salvage and thrombolysis CT venogram - suspect central ven thrombosis
49
hemorrhagic stroke mx
ABCs IV intubate LOC 94-98%; PaCO2 34-38mmHg BP 140SBP NBM - 30 degree normothermia, normogly reversal antigcoagulation a. Warfarin – Vitamin K, 4F-PCC, FFP. b. Dabigatran – Idarucizumab, 4F-PCC. c. Xa inhibitors – andexanat alfa, 4F-PCC d. Heparin/LMWH – Protamine sulfate craniotomy + clot evac/ ventricular drain a. Comatose patients with raised ICP. b. Large ICH with significant midline shift. c. ICH in brainstem/posterior fossa. d. Secondary hydrocephalus.
50
anticoag reversal
a. Warfarin – Vitamin K, 4F-PCC, FFP. b. Dabigatran (direct thrombin inhib) – Idarucizumab, 4F-PCC. c. Xa inhibitors – andexanat alfa, 4F-PCC d. Heparin/LMWH – Protamine sulfate
51
SAH mx cx of SAH
ottawa SAH rule - 6 criteria tRO SAH Hunt hess gradiing for SAH - survival on classiical sign prevent 2nd hemorrhage ABCs; IV; deteriorating; respi depression RSI ECG, CXR (neuro P edema) FBC, RP, PTaPTT, GXM SBP<160, MAP<110 - IV labetolol, IV nefedipine; no nitrates -- increases cerebral blood volume anticoag reversal ICP reduction 30, mannitol (no esrf); hypertonic NS Pain mx WHO, antiemetics ondansetron 4-9mcg, metoclopramide Antiseizure prophylaxius IV keprra Cx: rebleed; vasospasm; hydrocephalus; seizure Invx - - NCCT 6hr - LP 12h-12 days xantho; ct normal CTMRI angio - bleed confirmed Definitive management: a. Disposition to Neurosurgery or Neurology b. Temporizing measures for raised ICP: i. Hemicraniectomy, EVD if there is hydrocephalus. ii. Aneurysm repair with surgical clipping/endovascular coiling within 24 hours.
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meningitis pe invx mx
hx, PE immunocomp, travel, contacts petechia, purpura, jt pain isolation w PPE ABCs IV CBG, ECG, FBC, RP, culture, lact, DIVC (Meningco), ABG Abx Steroids 1. IV dexa 10mg 6hrly confirmed; GCS8-11 - hearing loss, focal def; 1st dose given 15min before chemoprophylaxis contacts - from 7 days rifampicin, Cipro, Ceft CT brain LP 5 tubes cell count, protein gluc, microbiology/AFB,TB,fungal, crypto/bacterial antigen, virology neuro isolation
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abx meningitis
immuno comp: <50 Strep, Nei, Hib, B, List, VZV Ceft 2g/12hr; vanco 15mg/kg C/V >50/compromised/pregant: S,L / N,Hib, B amp 2g 4hrly C/V + A Nosocomial Staph, strep, gram neg, Mero + Vanco M + V Meningogo IV pen G / IV Cef PG/C
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Abx for sepsis in 1. i. immunocompetent ii. compormised 2. CAP svere CAP 3. skin soft tissue; nec fasc 4. bact mening 5. male UTI/pyelo abdo infection biliary 6. septic shock community
1. ceft IV/cipro 200 C/C ceftaz 1g/ cipro+genta80mg Ct/C+G 2. IV aug+ POaz 500mg A+A ;; Aug + Ceft+IV Az 3. skin: IV cefaz 2g/ clinda600mg Cfz/Cl Nec: IV clinda + pen G + IV ceftazidime Cl+G+Cft 4. Ceft 2g 5. Aug1.2/Amik 10mg A+A Aug 1.2/ Ceft2g+Met500mg - A/ C+M 6. Clox2g + ceftaz2g + clinda 900mg ClCftCl
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glasgow blatch score
U<6.5 HB>13, >12 >110 SBP <100 BPM melena/syncpe no liver/cardiac failure 0: outpt >1: admit >6 - intervention
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PUD
TRO: AMI, AD, AAA, boerhaave, perf, cholangitis, abscess, pancr symptom: Anatacid - MMT, AlOH prokinetics - domperidone PPI - ome Disposition UGI bleed - hematem, coffee ground, meelna, fever jaundice -- GS Outpt: Chronic dspepsia > 40yo Wt loss, anemai, vomiting, hematemesis, melena, dysphagia, mass
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pancreatitis dx and mx
2/3: hx - back, epigastric 3x lipase CECT, MRI severity - glasgow imrie criteria ABCs, IV CBG, ECG, ABG FBC, RP, LFT, Ca, lact, coag, lipase CRP (>150mg/L in 24h - severe) Fluids - 250-500hartmannns AXR, E CXR, CT abdo NBM - severe; IDC IO analgesia - opioids anx with indications: infected panc necrosis cholangitis
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indications for NIV
COPD, bronchiec, OSA <7.35, PaCO2>45mmHg with meds NM disease VC <1L RR>20 or PaCO2>45 APO RR>25, SpO2<90 T1RF CPAP or t2RF BiPAP
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hepatic enceph classes mx of type a enceph
a - acute failure - substances - paracet, isonizaid, cocaine, ectasy - IV drigs - travel hep AE - Sex - hep B P1; ABCs RSI; ECG SpO2 Fluids NS NAC IV Seizure keppra CBG, FBC, RP, Coag, LFT tox CT head - cerebral edema ICU and liver team established liver cirrhosis B - Port system shunting c - cirrhosis stigmata of CLD Neuro exam - TRP EPSE (Akinesia, bradykinesai, slowness, dyskinesia) ABdo DRE - melena
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enceph grades
I-IV I: aware, anx, atention II: behavioral change, lethargy, III: confused stupor IV: coma
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precipitating events for type B and C hepatic enceph
hemorrhage GI E- hypoK, H+, hypogly Protein azotemia - tranquiliser sedatives infection - SBP; UTI pneumonia constipationn
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mx type b&c enceph
resuc ABCs RSI ECG, SpO2 IV NS precip cause; CBG, FBC RP, coag, LFT blood culture, urine paracenteiss CXR serum ammonia - support dx ABG - underlying cause lactulose 30ml PO or enema
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glasgow imrie criteria
3 or more in 48h PaO2< 8KPa Age >55 Neut > 15x10^9 Ca <2 renal > U>16 Enz LDH>600 AST 2000 ALb <32g sugar >10
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hypoglycemia
ABC IV ECG SpO2 CBG awake -- oral glucose IV D50 40ml if not IM glucagon 1mg chronic alcohol IV thiamine monitor >10mmol/L on 2 readings then 2 hourly; then 8 poor response --> repeat dextrose
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Thyroid storm
ABCs IV BB PO PTU Iodine Glucocorticoids hydrocort paracetamol
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Myxodema
hypothyroidism low GCS hypothermia hypoNa Hypovntilation hypogly bradycard + heart failure AMS + psychosis ABCs IV ECG CBG FBC, RP, CK, ABG, TFT, serum cortisol, sepsis workup CXR - cardiomegaly, effusion, edema, pneumonia Warm patient IV hydrocort -- stop if normal thyroid replacemtn IV levo treat cause -- hypoglycemia, hyponatremia, cardiac failure, sepsis
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SJS + TEN high risk drugs duration of onset presentation
allopurinol, lamotrigine, phenytoin, carbamazepine, antibiotics, NSAIDs, anti-retroviral and anti-TB medications s within 4 days to 4 weeks of ingestion of the drug URTI like symptoms + painfil skin rash over face and limbs + nikolsk sign
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Drug reaction with eosinophilia and systemic symptoms
high fever, extensive pruritic skin rashes visceral organ involvement, lymphadenopathy, eosinophilia, and atypical lymphocytosis Systemic steroids moderate PO pred severe - IV methypred + PO pred
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burns
ABCS intubation KIV salb/sux (within 72h) IDC; ECG hypo, GXM , FBC, RP, PT/aPTT, ABG, carboxyhaemoglobin and lactate levels if CO and CN poisoning is suspected. wallace rule of 9; lund browder chart fluid replacemnt -- parkland formula 2-4ml/kg/%BSA 2ml/kg/%totalBSA over 24 hours i. 1/2; 8h ii. 2nd 1/2 16 hours. analgesia + tetanus CO poisoning -- high flow O2 via NRM
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Nec fasc mx
ABCs IV FBC, RP, LFT, blood cultures, GXM, PT/aPTT XR, CT scan or MRI of the affected region IV benzylpenicillin + IV clindamycin + IV ceftazidime + Doxy vibrio Vanco -- MRSA refer ortho
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head CT rules for minor head injuries
GCS<15 suspect # skull BOS #, vomitting >2 >65yo Amnesia before impact >30 dangerous mechanism -- motor vehicle; ejection; fall from height >3ft
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NEXUS C spine clearance for low risk patients not requiring C spine clearance
- posterior midline c spine tenderness - NIL intoxication normal alertness NIL neruo deficit NIL painful distracting injury
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mx of moderate to severe TBI
C spine - NEXUS criteria ATLS - avoid NP airway NC CT brain seizure prophylaxis Raised ICP herniation mx 30', mannitol + hypertonic saline temporary hyperventilation manage pain, vomitting and sedation -- raised ICP normothermia EDH - craniotomy + hematoma evac SDH - craniotomy - if no swelling craniectomy - brain swelling craniostomy emergency
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HypoK severity
>5.5 Mild: <6.0 mmol/L and the ECG - normal or peaked Twaves Mod - 6-7; ECG peaked T waves Severe: 7-8; ECG P wave flat; widened QRS + T wave sine wave -- AV dissociation; (intervene here)
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indications of IV Calcium in HyperK
ECG severe hyperK -- >7 significant nm weakness
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UTI common organisms LUTI vs U UTI uncomplicated vs complicated UTI mx features of complicated UTI
PEKS E. Coli, Proteus, Klebsiella Staphylococcus saprophyticus. L UTI - urethritis, cystitis Dysuria, frectuency, haematuria, suprapubic discomfort pain, urgency, burning, cloudy urine with an offensive smell. U UTI: pyelonephritis, pyelonephrosis - Fever, loin and/or back pain, vomiting, rigors, malaise, sepsis/septic shock complicated UTI anatomically or functionally altered Ceft uncomplicated augmentin, nitro, cotrimox C- ANC complicated UTI: preg, renal impairment, immunosuppression, GU malformatin, hydronephrosis, renal transplant
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URolithiasis
pain crscnedo pain ; colicky ddx - AAA, appendicits, ectopic torsion dipstick ; pH>7.6 urea splitting organism uric acid stone pH<5 mx: pain control -- NSAIDs; hydration alpha blockers