Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

MRCP > Emergencies > Flashcards

Emergencies Flashcards

1
Q

Metabolic acidosis (raised anion gap) - causes

A

Aspirin – later metabolic compensation for high RR
CAT MUDPILES
C: CO, cyanide, congenital HF
A: Aminoglycosides
T: Theophylline, toluene
M: Methanol
U: Uraemia
D: DKA, alcoholicKA, starvationKA
P: Paracetamol, phenphormin, paraldehyde
I: Iron, isoniazid, IEOM
L: Lactic acidosis
E: Ethanol, ethylene glycol
S: Salicylates/aspirin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

DKA - management

A

Aà E
AIM TO REDUCE KETONES
(1) Fluids (500mL bolus over 15m if SBP <90 until >90 mmHg, otherwise 1L NaCl / hour)
(2) Insulin (0.1U/kg/hr fixed rate IV insulin infusion + patient’s normal insulin regimen) – start after fluids started
(3) Potassium (only if/when low - check K+ on latest VBG, insulin causes hypokalaemia à run 40mmol KCl with second bag of NaCl over 2hrs)
(3) 10% dextrose (when BM <14), 100mL/hour
(4) VTE prophylaxis (very dehydrated)
Throughout: Monitor obs, glucose, ketones, VBG/ABG (pH, HCO3, K+)
Even if the patient is tipping into lower glucose levels, you can still give insulin – just give dextrose as well

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

DKA - management - K replacement

A

K>5.5 - nil
K 3.5-5.5 - 40mmol
K<3.5 - higher K concentrations, call ITU for central line
Max 20mmol/hr (therefore add to 2nd bag at the earliest)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

HHS - diagnosis

A

pH >7.3, osmolarity >320mOsm, BM >30 mmol/L – develops over a few days - 1 week

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

HHS - investigations

A

Bedside:
ECG
Urinalysis +/- MSU
Urinary pregnancy test
CBG
Bloods: FBC, U&Es, CRP, LFTs, plasma glucose, blood culture, troponin, amylase, CK, Ca
CT Head (if focal neuro)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

HHS - management

A

(1) Slow rehydration over 48hrs (3-6L in 12hrs) as level of dehydration can be massive in HHS; i.e. initial fluids…
Sodium chloride 0.9%, 1L, IV, over 2 hours
½ RATE OF FLUIDS OF DKA
(2) Monitoring (avoid rapid correction Na+, neurological status, every 4hrs: electrolytes, urea, blood glucose)
(3) Insulin (0.05U/kg/hr) sliding scale once BMs stop dropping OR ketones start to rise (i.e. once stabilised)
Fixed rate insulin infusion if evidence of ketonaemia
Replace K+ when UO increases
(4) Specialist review (within 24hrs) + begin prophylactic LMWH

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

HHS - treatment targets

A

Plasma osmolality target: falling by 3-8mOsm/kg/hr
Blood glucose/L falling by at least 5mmol/L/hr

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Posterior MI - ECG changes + coronary artery

A

Tall R waves in V1-2
Usually left circumflex, also right coronary

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Right coronary artery MI leads to…

A

Inferior MI
AV/Heart block (supplies AVN) - any degree

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

STEMI - ECG criteria

A

ST elevation >1mm in 2 consecutive limb leads,
Or >2mm elevation in 2 consecutive chest leads
Or new LBBB

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

NSTEMI - ECG criteria

A

Anything that doesn’t fit STEMI criteria, can have ECG changes i.e. ST depression or T wave inversion.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Silent MI - presentation

A

Silent MIs = diabetics or elderly à syncope, epigastric pain, vomiting, delirium, post-op oliguria/hypotension

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

When to do PCI vs CABG

A

PCI à 1- or 2-vessel disease, not including Left main stem
CABG à 2- or 3-vessel disease, or including Left main stem
If not clear cut –> MDT

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

ACS - investigations/diagnosis

A

Basic observations
ECG/Cardiac monitoring
Serial ECGs are useful to monitor for ST segment or T wave changes [dynamic changes]
Bloods
Troponin I/T
FBC, U&Es, glucose, lipids, clotting
CXR à cardiomegaly, pulmonary oedema, widened mediastinum (aortic rupture/aortic dissection)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

STEMI - ECG changes sequence

A

Sequence:
Normal
ST elevation +/- tall T waves
Q waves (full thickness infarcts)
normalisation of ST segments
T wave inversion
Also new LBBB can indicate acute MI

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

NSTEMI - ECG changes

A

NSTEMI: ST depression, T wave inversion

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

ACS - acute management - generic

A

Admit + cardio review
Medication: MONA (morphine, oxygen, nitroglyceride, aspirin)
M: IV diamorphine 5-10mg (+ IV metoclopramide) = only if severe chest pain otherwise paracetamol
O2: non-rebreather mask if sats <92%, aim sats for 94-98% (if COPD then 88-92%)
N: GTN spray for pain
A: DAPT STAT (300mg aspirin + 300mg clopidogrel/180mg ticagrelor/prasugrel)
Anticoagulation (Fondaparinux 2.5mg SC OD) for 2-8 days until discharge or revascularisation - NOT if PCI possible

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

Why give ticagrelor over prasugrel?

A

Most people give ticagrelor because its faster than prodrug clopidogrel

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

ACS - long-term management - antiplatelets

A

75mg OD aspirin lifelong
Medically managed - ticagrelor for 12mo
PCI managed - clopi/prasugrel/ticagrelor for 12mo (decreases risk of stent thrombosis)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

ACS - acute management - STEMI

A

PCI available: PCI within 120 mins of presentation (give prasugrel if no AC/clopi if on AC)
PCI unavailable: thrombolysis within 12h of presentation, ECG after 60-90 mins - if STEMI still, rescue PCI/angiography
>12h since symptom onset: specialist advice + anticoagulants (fonda/enox) + angiography + PCI

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

DAPT - SEs

A

Dyspepsia - give PPI

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

GTN spray - SEs

A

hypotension, headache, tachycardia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

ACS - acute management - NSTEMI

A

Aspirin + serial ECGs + fondaparinoux if no immediate PCI
GRACE >3% - PCI within 72h (give ticagrelor/prasugrel + heparin)
GRACE <=3% - ticagrelor but no PCI
Clinically unstable - immediate PCI

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

Antiplatelet bleeding risk

A

Prasugrel > ticagrelor > clopidogrel
If bleeding risk, use clopi

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
Q

ACS - acute management - UA

A

Same as ACS treatment = aspirin + clopidogrel and fondaparinux

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
26
Q

What does GRACE score measure?

A

6-month mortality for pts with ACS

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
27
Q

Raised troponin I/T - causes

A

MI, CKD, HF, sepsis, CA spasm, aortic dissection, PE

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
28
Q

ACS - acute management - anticoagulant choice

A

Angiography ± PCI <24 hours - 1st line: enoxaparin (LMWH) OR unfractionated heparin OR bivalirudin
Fibrinolysis - 1st line: enoxaparin (LMWH) OR unfractionated heparin OR fondaparinux 2.5mg SC OD
No intervention (low GRACE) - 1st line: fondaparinux (AKA always give in NSTEMI)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
29
Q

ACS - long-term management

A

Lifestyle: mediterranean diet, exercise 20-30 mins/day, no sex 4 weeks, no viagra 6 months
Medical: ACEi, BB/RLCCB, DAPT, antiHTN, statin
HF S/S - consider spironolactone

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
30
Q

Beta-blockers - CIs

A

low BP/HR, HF, COPD/asthma, cardiogenic shock, heart block

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
31
Q

Suspected MI - GP referral criteria

A

Pain <12h ago + abnormal ECG à A&E now
Pain 12-72h ago à same day assessment
Pain >72h ago à ECG + troponin

32
Q

PCI - indications

A

CAD, valvular disease, congenital heart disease

33
Q

PCI - complications

A

haemorrhage, reaction, angina, arrhythmias

34
Q

CABG - methods

A

LIMA diverted to LAD post-occlusion
Great saphenous vein harvested + attached to aorta + coronary artery post-occlusion
Both
Heart stopped + blood pumped artificially by bypass

35
Q

MI - complications

A

Death
Arrhythmia
Rupture (left ventricular free wall rupture, interventricular septum rupture à VSD)
Thrombus
Haemorrhage
Valvular heart disease
Aneurysm (left ventricular wall; LAD involvement)
Dressler’s syndrome (2-6 weeks), pericarditis (<48 hours)
Embolism
Re-infarct

36
Q

MI - arrhythmias it can cause

A

Heart block:
- Inferior MI mx: medical management (atropine; fatigue of AV nodal cells can be reversed)
- Anterior MI mx: temporary TC pacing à permanent pacemaker

Tachy-/brady-arrhythmias (VF = most common cause of death post-MI)

37
Q

MI - types of rupture

A

Acute / 3-5 days à acute mitral regurgitation (PAPILLARY MUSCLE RUPTURE; RCA)
Acute / 3-5 days à ventricular septal rupture (LAD or RCA)
5 days – 2 weeks à LV free wall rupture (LAD)

38
Q

MI - acute MR

A

Acute / 3-5 days
PAPILLARY MUSCLE RUPTURE; RCA)
S/S: pulmonary oedema, hypotension, new PSM [no thrill, soft murmur]

39
Q

MI - ventricular septal rupture - presentation + investigations

A

Acute / 3-5 days
LAD or RCA
S/S: chest pain, biventricular failure (acute HF), shock, new PSM [thrill, harsh murmur]
Ix: echo (exclude acute mitral regurgitation)

40
Q

MI - LV free wall rupture - presentation

A

5 days – 2 weeks
LAD
S/S: HF, tamponade (raised JVP, muffled heart sounds, hypotension, pulsus paradoxus)

41
Q

MI - aneurysm - presentation + management

A

left ventricular wall; LAD involvement
S/S: SOB, PERSISTENT ST-ELEVATION, no chest pain, LVF (à thrombus), maybe S3 & S4
Mx: anticoagulation

42
Q

MI - Dressler’s syndrome/pericarditis - presentation

A

Dressler’s syndrome (2-6 weeks) (NOTE: pericarditis is <48 hours after MI)
S/S: fever, pleuritic pain, pericardial effusion, raised ESR

43
Q

MI - Dressler’s syndrome/pericarditis - management

A

Mx: NSAIDs (ibuprofen) or Aspirin. 2nd line: Colchicine or corticosteroids

44
Q

MI - reinfarct - investigations

A

If ?re-infarct 4-10 days after initial MI, use CK-MB (raised for 3-4d) instead of troponin (raised for 10d)

45
Q

MI - predicting/stratifying prognosis

A

Killip classification

46
Q

Acute pulmonary oedema - causes

A

Cardiovascular (LVF: post-MI, VHD e.g. MR) à elevated PAWP
ARDS (RFs: in trauma, malaria, drugs) à normal PAWP
Fluid overload
Neurogenic (head injury)

47
Q

Acute pulmonary oedema/acute heart failure - initial management

A

ABCDE
C/I drugs: STOP BB if HR <50/min, second/third degree AV block or shock
Sit them up à high-flow (15L) O2 (if SpO2 decreased)
IV access + continuous cardiac monitoring + monitor obs + UO + ECG
IV diamorphine (3mg) + IV metoclopramide (10mg) [caution in liver failure and COPD] - venodilator + anxiolytic
IV furosemide (40-80mg) [larger dose in renal failure] - venodilator –> diuretic
SL GTN spray x2 puffs [if SBP ≥100mmHg, use IV GTN] - venodilator
Consider inotropes e.g. dobutamine à vasopressors if unresponsive e.g. noradrenaline
Further management:
Further furosemide [40-80mg]
Further nitrate infusion (isosorbide dinitrate) [maintain SBP ≥90, if it drops <100, treat as per cardiogenic shock]
CPAP / ITU admission

48
Q

Acute pulmonary oedema - management once stable

A

Daily weights
Repeat CXR
Manage medications:
Change to oral furosemide
Consider thiazide (if on high doses of furosemide)
ACEi (LV-EF <40%), beta blocker (LV-EF <35%),
Spironolactone

49
Q

Acute pulmonary oedema - investigations

A

Ix: ECG –> ABG, BNP –> CXR

50
Q

Indications for permanent pacemaker

A

Pacemaker: HB T3, HB T2 MII, HB T2 MI with symptoms, bradycardia, HF, drug-resistant tachy-arrhythmia, bi/tri-fascicular block with symptoms, sick sinus syndrome with symptoms

51
Q

MI - acute MR - management

A

Mx: inotropes/vasopressors, surgery*

52
Q

MI - ventricular septal rupture - management

A

Mx: analgesia, coronary angio, intra-aortic balloon pump, inotropes/vasopressors, surgery (urgent transfer)

53
Q

MI - LV free wall rupture - management

A

Mx: pericardiocentesis + thoracotomy

54
Q

Cardiogenic shock - causes

A

MI [tx as per STEMI]
Arrhythmias
Cardiac tamponade
PE, tension-pt
Myocarditis
Valve destruction
Aortic dissection

55
Q

Cardiac tamponade - management

A

Senior review
Pericardiocentesis

56
Q

Cardiogenic shock - investigations

A

ECG, ABG, CXR, echocardiogram
FBC, U&Es, troponin, BNP, UO [catheterise]
Consider CVP (Swan-Gantz catheter) + arterial lines

57
Q

Cardiac tamponade - presentation + ECG changes

A

Beck’s triad = hypotension, raised JVP, muffled sounds
ECG = electrical alternans
Cannot get pulmonary oedema on CXR because the heart will stop before this happens

58
Q

Cardiogenic shock - management

A

A-E
Analgesia
Correct arrhythmias, electrolytes, acid-base
Optimise filling pressure: fluids if hypovolaemic, inotropes of normo/hypervolaemic
Consider Swan-Gantz catheter
Aim MAP 70mmHg, CVP 8-10mmHg

59
Q

Central venous line - complications

A

Immediate: pneumothorax, arrhythmia, failure, air embolus, bleeding, perf., misplacement
Early: bruise, infection, occlusion
Late: thrombosis, Horner’s, phrenic nerve damage, sepsis, venous stenosis

60
Q

Pericardiocentesis - needle entry points

A

Left sub xiphisternal/diaphragmatic approach (pointing towards left shoulder/nipple)
Left 5th ICS near sternal border

61
Q

Cardiac tamponade vs constrictive pericarditis

A

JVP
Cardiac tamponade: absent Y descent; constrictive pericarditis: X+Y present
Pulsus paradoxus in cardiac tamponade
Kussmaul’s sign in constrictive pericarditis

62
Q

Broad complex tachycardia - causes

A

VT
SVT with aberrant conductions (i.e. AF with BBB – likely if patient stable)
Pre-excited tachycardia (i.e. AF with underlying WPW)

63
Q

Narrow complex tachycardia - causes

A

Sinus tachycardia
SVT (all of the below):
- AVNRT (most common)
- AVRT (due to WPW)
- AF / flutter
- Atrial tachycardia (usually 2:1)
- Multifocal atrial tachycardia
- Junctional tachycardia

64
Q

Adult ALS algorithm

A

Unresponsive + not breathing –> call for help + 2222 + start CPR (30:2)
Shockable rhythm: non-synchronised shock (defibrillation) every 2 mins, IV adrenaline 1mg + IV amiodarone 300mg after 3 shocks. Repeat adrenaline every 3-5 mins. Amiodarone 150mg after 5 shocks.
Non-shockable rhythm: IV adrenaline 1mg immediately. Repeat adrenaline every 3-5 mins

65
Q

Adult ALS algorithm - hypothermia

A

Max 3 shocks before warming to above 30C
Withhold drugs until at least 30C

66
Q

Types of shock to use

A

Synchronised DC shock (cardioversion): unstable tachycardia (i.e. with shock/syncope/MI/HF - but NOT VF or pulseless VT)
Non-synchronised DC shock (defibrillation): cardiac arrest i.e. VF, pulseless VT

67
Q

Normal CVP

A

0-6mmHg

68
Q

Types of VT

A

monomorphic VT: usually due to MI
polymorphic VT: e.g. TdP secondary to long QTc

69
Q

Contraindications in ventricular tachycardia

A

CI: verapamil (also CI in chronic HF as can precipitate AHF)

70
Q

Defibrillation - when to give stacked shocks

A

if the cardiac arrest is witnessed in a monitored patient (e.g. in CCU) then perform ‘up to 3 quick successive (stacked) shocks’ followed by CPR

71
Q

Adult ALS algorithm - thrombus

A

If PE –> alteplase
If alteplase given, CPR should be continued for 60-90 minutes

72
Q

Torsades de Pointes - management

A

Drug-induced à 2g Mg sulphate over 10mins
Correct any electrolyte abnormalities and stop drugs prolonging QT interval (which leads to TdP)

73
Q

Differentiation between VT vs [SVT with BBB]

A

Fusion/capture beats (P waves that have gotten through to the ventricles via the AVN) = VT
If unsure, treat as VT
in SVT with BBB, blocking AVN pauses tachycardia

74
Q

Bradycardia - causes

A

Physiological
Cardiac (i.e. post-MI, sick sinus syndrome, aortic valve disease, cardiomyopathy, sarcoid)
Non-cardiac (i.e. vasovagal, hyperkalaemia, hypothermia, raised ICP ‘Cushing’s triad’, hypothyroid)
Drug-induced (beta blockers (if beta blocker OD, give glucagon), amiodarone, verapamil, diltiazem, digoxin)

75
Q

Bradycardia - management algorithm

A

A-E
Unstable (shock/syncope/MI/HF) or risk of asystole: IV atropine 500mcg, repeat up to 3mg max
Interim measures: isoprenaline, adrenaline, aminophylline, dopamine, glucagon if BB/CCB overdose, transcutaneous pacing
Senior: transvenous pacing
No risk of asystole: observe

MRCP (19 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions