Emergency & acute med 3 Flashcards
(169 cards)
Common causes of seizures? 9
- epilepsy (incl poor compliance to meds)
- drugs (incl recreational)
- alcohol withdrawal
- low sodium or blood sugar
- infection (meningitis, encephalitis)
- high fever (esp in kids)
- head injury / raised ICP (?SAH)
- brain tumours / mets
- pregnancy related - eclampsia etc (consider in women of child-bearing age)
If someone presents after a seizure, what questions should you ask them? (before 2, during 5, after 4)
- important PMH/FHx to ask? 2
- What to ask if had seizure before / known epilepsy?
BEFORE
- Any aura? Changes in smell, taste, headaches, - is this familiar to the patient?
- any triggers? what were you doing?
DURING
- Does it sound tonic-clonic? Were they jerking? describe it (need collateral if poss)
- LOC?
- Tongue biting (tip or side)
- Incontinence
- how long did it last?
AFTER
- Are they sleepy? Drowsy? Confused? Dizzy? Nauseous?
- for how long afterwards
- Headache
- Weakness
- any other injuries?
1) Have you ever had this before?
2) Any FHx of epilepsy
3) What was DIFFERENT from previous seizure? (eg length, type of seizure etc)
What is the difference between:
- simple and complex seizures?
- partial and generalised seizures?
Simple = NO LOC Complex = LOC
partial = focal deficit generalised = whole brain
Types of partial seizure? 3
SIMPLE PARTIAL SEIZURE
- Awareness is unimpaired, there is focal motor, sensory of autonomic symptoms and no post-ictal symptoms
COMPLEX PARTIAL SEIZURE
- Awareness of the period has been impaired. Focal symptoms during an aura. These most commonly arise from the temporal lobe and if there is an aura then this is supportive of this.
Common to have post-ictal confusion in seizures of the temporal lobe but recovery is more rapid in seizures arising from the frontal lobe
PARTIAL SEIZURE WITH SECONDARY GENERALISATION
- 2/3 of patients who have a focal seizure will have a generalising transformation which typically presents as convulsions
Types of primary generalised seizures? 4
PRIMARY GENERALIZED SEIZURES
ABSENCE SEIZURES
Brief pauses where the person stops what they are doing/saying for ten seconds or less and then starts again (make sure you ask about these in the history). These will commonly present in childhood
TONIC-CLONIC SEIZURES
L.O.C. Limbs stiffen (tonic) and then jerk (clonic) in turn. You can have one without the other: there is usually a considerable post-ictal period with confusion and dizziness
MYOCLONIC SEIZURES
Sudden jerk of the limb or the face or the trunk. The patient may fall to the ground or have a violently disobedient limb
ATONIC SEIZURES
Sudden loss of muscle tone and fall to the ground (no LOC)
Triggers of seizures in known epileptics? 7
- poor medication compliance
- lack of sleep
- stress
- missing meals
- alcohol or recreational drugs
- illness / infection
- flashing lights (only 3% of people w epilepsy)
(also menstrual cycle can affect too)
Management of someone having a seizure in the ED:
- Approach?
- positioning and initial 2 interventions?
- when to give medication and options of what to give 1st line?
- 2nd line medication?
- 3rd line medication?
- 4th line medication?
- when to alert anaesthetist? 2
- bloods? 5
- what to make sure to do as part of ‘exposure’? 2
- what other meds to consider giving? 2
A-E approach
- recovery position (and remove tight fitting clothing)
- nasopharyngeal airway
- high flow oxygen
WAIT 5 MINS (time it!)
then give either:
- IV lorazepam
- buccal midazolam
- rectal diazepam
WAIT 10 MINS
- give 2nd dose of benzos (don’t give more than 2 doses as can lead to resp depression)
WAIT 10 MINS
- loading dose then infusion of phenytoin
WAIT 10 MINS
- give propofol or thiopentone (neuroprotective)
ALERT ANESTHETIST
- when GCS <8
- when about to give phenytoin
- ABG
- glucose
- FBC
- UandE
- blood cultures, if pyrexial
(other bloods as well probs - could justify most) - check for rashes or fever (meningitis) or head injury signs
- glucose (if hypoglycaemic)
- pabrinex (thiamine - if suggestion of alcohol abuse or malnutrition)
What are the 2 definitions of status epilepticus?
continuous seizure lasting >30mins
OR
repeated seizures with breaks but GCS stays <15 in breaks
nb it may start tonic clonic then diminish making diagnosis difficult (coma and minimal twitching only )
- can also get non-convulsive status epilepticus - hard to diagnose (need eeg)
Who should get a CT head following a seizure?
Which of these should be done as an emergency?
Following any ‘first fit’
emergency:
- focal signs
- head injury
- known HIV
- suspected intracranial infection
- bleeding disorder
- conscious level failing to improve
What additional test should you do for women of childbearing age who have a seizure?
pregnancy test
as may be sign of pre-eclampsia
if pregnancy-related fit = us IV magnesium sulphate
If patient has a ‘first fit’ - when are they allowed to be discharged? 4
What is the follow-up? 1
what advice must be given in the interim, before follow up? 1
who must be admitted and not discharged?
- normal neuro exam
- normal cardiac exam
- ECG normal
- electrolytes normal
follow up appointment in ‘first fit’ clinic
not allowed to drive until have seen specialist
if multiple seizures, admit
Definition of a stroke?
Acute onset of neurological deficit lasting >24 hours (if it is less then it is a TIA), of VASCULAR origin.
Symptoms/signs of anterior circulation stroke? 6 (also which arteries norm affected)
Symptoms/signs of posterior circulation stroke? 7 (also which arteries norm affected)
ANTERIOR = branches of internal carotids - unilateral limb weakness - unilateral numbness / loss of sensation - unilateral facial droop - speech disturbances - cognitive impairment - visual field disturbances
POSTERIOR = branches of basilar artery (so affect the cerebellum!!) - nausea - dizziness / vertigo - memory loss - lack of coordination - ataxia / loss of balance / gait change - limb weakness - sensory deficits bilaterally
Stroke: examination:
- approach?
- examinations to do? 5
- what else to assess, for safety?
A-E approach (incl GCS)
- Cranial nerve
- UL neuro
- LL neuro
- cerebellar exam
- cardiac exam (carotid bruits, murmurs, AF)
- assess pts swallow, if not okay make NBM
Investigations:
- score to use for TIA? 1
- score to use for stroke? 1
- bedside? 1
- bloods? 3
- imaging? 1
- bloods to consider? 1
ABCD2 score for TIA
Rosier score for stroke
- ECG (looking for AF)
- FBC
- UandE
- glucose (always exclude hypoglycaemia)
CT head (non-contrast) - whether is emergency or not depends on timing of presentation and other factors
ABG (if sats <94%)
Who gets an emergency CT head following a stroke:
- timing of presentation? 1
- other indications? 7
If patient presents WITHIN 4 HOURS of symptoms
- as may be able to thrombolyse
- patient is on anti-coagulant
- severe headache at onset
- fever
- neck stiffness
- GCS <13
- unexplained progressive or fluctuating symptoms
- papilloedema
nb pretty much all patients with a stroke get a CT at some point
Possible management options for stroke? 3
- who is eligible for each?
nb the first two can only be given at places with specialist stroke services!
THROMBOLYSIS (alteplase)
- if can start within 4.5 hours of symptom onset
AND
- if intra-cranial haemorrhage has been excluded by CT
THROMBECTOMY
- if thrombotic stroke of PROXIMAL anterior or posterior circulation confirmed (using CT or MRI angiography)
AND
- presentation within 24hrs
AND
- there is potential to salvage brain tissue, as shown by imaging
ASPIRIN (300mg)
- give to EVERYONE who presents within 24hrs following stroke
AND
- haemorrhagic stroke excluded by CT
- followed by maintenances dose anti-platelet for weeks
- nb give PPI as well if dyspepsia risk factor
sub-arachnoid haemorrhage:
- description of headache?
- other symptoms? 6
- What PMHx and FHx to ask about?
- SUDDEN onset (biggest clue!)
- very severe
- feels localised to back of head
- feels like being hit over back of head with something
- LOC (15% only present with this!)
- neck pain
- photophobia
- VOMITING
- drowsiness and confusion
- unilateral eye pain can occur
nb in 25% of cases, exertional activities precede the event
1) pmhx HTN?
2) Any FHx of aneurysms or strokes?
Sub-arachnoid haemorrhage:
- which examinations to do? 4
- what is most common exam finding?
- what important to look at in the obs? 3
- why?
- cranial nerve exam
- UL neuro
- LL neuro
- cerebellum exam
oculomotor nerve palsy (characteristic of a berry aneurysm in posterior communicating artery)
- increase in BP
- bradycardia
- irregular breathing
= cushings triad / response
= sign of raised ICP
Sub-arachnoid haemorrhage:
- approach?
- bedside investigations? 2
- bloods? 4
- imaging? 1
- what to do if imaging normal? 1
A-E approach
- fundoscopy
- ECG (ischaemic changes)
- glucose
- FBC
- UandE
- CLOTTING
- emergency head CT
if CT normal, do an LP after 12 hours - looking for xanthochromia in the CSF
Sub-arachnoid haemorrhage management:
- what to keep monitoring? 1
- immediate medication? 4
- which teams to involve? 2 (when?)
- monitor O2 sats - give O2 if low
- analgesia
- anti-emetic
- NIMODIPINE (as soon as SAH confirmed - repeat every 4 hrs, prevents vasospasms)
- MANNITOL (if evidence of increased ICP)
- neurosurgical team (once diagnosis confirmed by CT)
- anaesthetist (if GCS <8 or very agitated)
Syncope: definition?
symptoms of vasovagal syncope? (before 5, during 2, after 1)
what other question if it really important to ask in the context of syncope?
ideally what other type of history should you obtain in a pt with syncope?
sudden TRANSIENT LOC with SPONTANEOUS complete recovery
BEFORE - feel unwell / nauseous - feeling warm - light-headed - palpitations - blurred vision / dots in vision DURING - short LOC - no side-tongue biting, may be tip of tongue or myoclonic jerks, esp if person can't get supine AFTER - fast recovery - within 5 mins
WHAT WERE YOU DOING AT THE TIME? (exertional syncope is not a good sign)
get collateral hx - if possible!
Examination for syncope:
- what sort of exams should you do? 2
- what other specific features should you look for? 3
- what causes of syncope must you not miss? 6 (acronym and how to exclude each)
- full cardiac exam
- full neuro exam
- signs of tongue biting
- incontinence
- any injuries
A PEARS
ACS
- ecg and troponin
PE
- risk factors, wells score
Ectopic pregnancy
- ask about abdo pain and vaginal bleeding in women of CBA
Aortic dissection
- BP in both arms
Ruptured AAA
- abdo pain, feel for expansile pulsatile mass in abdomen
SAH
- signs of meningeal irritation
Syncope investigations:
- bedside? 2
- bloods? 3
- ECG
- lying and standing BP
- glucose
- FBC (anaemia big cause)
- UandE