Emergency Medicine ACC Flashcards
(221 cards)
At what time should a troponin level be taken and at what time does it peak?
Troponin should be taken atleast 6 hours after the maximal onset of pain, peaks at 24-48 hours
what is the difference between unstable angina and a NSTEMI?
Unstable angina = normal troponin
NSTEMI = rise in troponin
What is the ECG criteria for a STEMI?
New or presumed new ST-segment elevation at the J point in 2 or more contiguous leads with the cut-off points of ≥0.2 mV in leads V1, V2, or V3 and ≥0.1 mV in other leads. Note: ST depressions in leads V1-V4 should be considered as a posterior STEMI.
in which leads are the ECG changes inferior MI? (RCA)
leads II, III, avF
in which leads are the ECG changes anterior MI?
leads V1-V4
in which leads are the ECG changes lateral MI? (circumflex artery)
V5,V6, I and aVL
What are the common ECG changes in a STEMI?
ST-segment elevation Pathological Q waves (>1mm) St-segment depression PR segment elevation/depression New bundle branch block Axis deviation T wave inversion T wave depression
Which creatinine kinase enzyme is found in the heart and when does it peak?
CK-MB
48 hours
Which investiagions are most appropriate in suspected MI?
ECG.
U&E, troponin, glucose, cholesterol, FBC
CXR
What is the most appropriate treatment in a STEMI?
Aspirin + Clopidogrel/Tigagrelor Morphine (+antiemetic) GTN O2 Primary PCI or Fibrinolysis Anticoagulation - injectable anticoagulant in primary PC, if not give enoxaparin +/- GP IIb/IIIa blocker
What is the most appropriate treatment in a NSTEMI?
Dual anti platelet therapy Anticoagulation - fondaparinox 2.5mg daily or enoxaparin Glycoprotein IIb/IIIa inhibitors Nitrates B-blockers - if increased HR ACEi Lipid management
Which drugs are necessary in secondary prevention of MI?
ACEi
Dual anti platelet therapy = aspirin + 2nd anti platelet agent
Beta-blocker
Statin
what type of drug is fondaparinux?
Factor Xa inhibitor
What are the criteria for a massive PE?
Hypotension
Cardiac arrest
*require thrombolysis
What are the criteria for a submassive PE?
Hypoxia
Cardiac ECHO or ECG feature of right heart strain]
Positive cardiac biomarkers (eg. troponin)
Which score is used for risk stratification of pulmonary embolism after the diagnosis has been made?
PESI score: pulmonary embolism severity index. Use to classify and determine treatment/hospital stay.
If PE is confirmed but is not submissive or massive use PESI score to determine hospital stay
What are the possible ECG changes seen in PE?
Sinus Tachycardia RBBB Right axis deviation (most common) S1Q3T3: prominent S wave in lead 1 A Q wave and inverted T wave in lead 3
When is a D-dimer not useful?
After surgery
Trauma
Sepsis
Pregnancy
In a well’s score for PE what is considered high risk and low risk scores??
Score >4
Do a CTPA
Score <4
Do a D-dimer - if positive do a CTPA
When is a V/Q scan used to diagnose PE?
In pregnancy, young women
What are the investigations used in suspected PE?
FBC, U&E, D-dimer, ECG CXR CTPA V/Q scan USS lower limb - if results do not confirm clinical suspicion
What is the most appropriate treatment for a PE?
O2
Start LMWH when PE is suspected
Start warfarin when PE is confirmed, continue LMWH until INR is therapeutic (2-3)
Analgesia
IV fluids if hypotensive
If evidence of haemodynamic instability: consider thrombolysis (alteplase, streptokinase)
For how long should anticoagulation therapy be continued following PE?
6 weeks if temporary risk factor
3 months for 1st idiopathic causes
at least 6 months for other causes
In an unprovoked PE what should be done?
Set of investigations set out by guidelines. 5% with PE will have an active malignancy