Endo diseases - thyroid diseases

Question 1

2 types of autoimmune thyroid diseases

Answer 1

graves = hyper
Hashimotos thyroiditis = hypo

Question 2

Graves = what autoantibodies ?

Answer 2

Thyroid- stimulating autoantibodies (TSAb)

= bind to TSH receptor

Question 3

TRH, TSH, T3 and T4 levels in graves

Answer 3

TRH and TSH low
the other 2 high

Question 4

what is big eyes called

Answer 4

thyroid associated opthalmopathy

Question 5

what drug treatment ofor graves

Answer 5

thionamide drugs
e.g. carbimazole
blocks T4 synthesis
inhibits TPO catalysed iodination of thyroglobulin icl i forgot what that even is

Question 6

more preffered treatment of graves

Answer 6

surgery
radioactive iodine

both lead to hypothyroidism so need replacement T4 tablets

Question 7

hashimotos thyroiditis

Answer 7

autoantibodies will destroy thyroid tissue

Question 8

endemic iodine deficiency

Answer 8

lack of iodine in diet
or
ingestion of goitrogens

Question 9

why can lack of iodine in diet of mum be bad for baby

Answer 9

important in developing foetal tissues, mainly brain