endo repro Flashcards

(90 cards)

1
Q

What are the 6 types of chemical messengers?

A

Neurotransmitters, Endocrine hormones, Neuroendocrine, Paracrines, Autocrines, Cytokines

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2
Q

Which hormone classes are water-soluble?

A

Peptides and some amines (e.g., epinephrine)

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3
Q

How are peptide hormones stored?

A

In secretory vesicles and released via exocytosis

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4
Q

From what are steroid hormones synthesized?

A

Cholesterol

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5
Q

What is the most common feedback mechanism in the endocrine system?

A

Negative feedback

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6
Q

Which hormone exhibits positive feedback during ovulation?

A

Luteinizing hormone (LH) due to estrogen

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7
Q

What brain structure regulates circadian rhythm?

A

Suprachiasmatic nucleus (SCN)

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8
Q

Where are steroid hormone receptors located?

A

In the cytoplasm or nucleus

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9
Q

What second messenger does adenylyl cyclase produce?

A

cAMP

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10
Q

What does IP3 do in the cell?

A

Releases calcium from intracellular stores

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11
Q

What hormones does the anterior pituitary secrete?

A

GH, TSH, ACTH, LH, FSH, PRL

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12
Q

What gland produces T3 and T4?

A

Thyroid gland

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13
Q

What hormone increases blood glucose and is secreted by alpha cells?

A

Glucagon

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14
Q

How are steroid hormones transported in the blood?

A

Bound to plasma proteins

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15
Q

What is ELISA used for?

A

Measuring hormone levels using enzyme-linked antibodies

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16
Q

What hormone triggers ovulation?

A

LH surge

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17
Q

What cells produce testosterone in males?

A

Leydig cells

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18
Q

What placental hormone maintains the corpus luteum?

A

Human chorionic gonadotropin (hCG)

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19
Q
A
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20
Q

Front

A

Back

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21
Q

What is the endocrine system composed of?

A

Endocrine glands and specialized endocrine cells throughout the body.

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22
Q

How do endocrine glands release hormones?

A

They secrete hormones into the bloodstream, not through ducts.

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23
Q

What are target tissues?

A

Tissues with specific receptors for hormones that produce a response.

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24
Q

Name some small organs that function as hormone factories.

A

Thyroid, pancreas, adrenal glands.

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25
What are water-soluble hormones?
Hormones that dissolve in water and bind to receptors outside the cell membrane.
26
What are examples of water-soluble hormones?
Insulin, adrenaline, glucagon.
27
How are water-soluble hormones transported?
Freely in the bloodstream without binding proteins.
28
Are water-soluble hormones easily broken down?
Yes, they are easily removed by enzymes and broken down.
29
What are lipid-soluble hormones?
Hormones that dissolve in fats and bind inside the cell.
30
Examples of lipid-soluble hormones?
Estrogen, cortisol, thyroid hormone.
31
Why do lipid-soluble hormones need binding proteins?
Because they don’t mix well with water and require transport in blood.
32
Can lipid-soluble hormones pass through the cell membrane?
Yes, they pass through the lipid bilayer easily.
33
What are the 3 main stimuli for hormone release?
Humoral, Neural, and Hormonal stimuli.
34
Describe humoral stimuli.
Chemical changes in the blood trigger hormone release (e.g., low calcium → PTH).
35
Describe neural stimuli.
Nerve impulses stimulate hormone release (e.g., stress → adrenal medulla).
36
Describe hormonal stimuli.
Hormones from one gland stimulate another gland (e.g., HPA axis).
37
What is the pituitary gland also called?
Hypophysis.
38
Where is the pituitary gland located?
At the base of the brain below the hypothalamus.
39
Why is the pituitary called the master gland?
Because it controls several other endocrine glands.
40
What are the two parts of the pituitary?
Anterior (adenohypophysis) and Posterior (neurohypophysis).
41
Which hormones are secreted by the anterior pituitary?
Prolactin, GH, MSH, TSH, ACTH, FSH, LH.
42
What is the function of prolactin?
Promotes milk production in females.
43
What happens with excess prolactin in males?
Erectile dysfunction.
44
What does growth hormone regulate?
Growth and metabolism; abnormalities cause gigantism or dwarfism.
45
What is the role of MSH?
Stimulates melanocytes to produce pigment.
46
What does TSH do?
Stimulates thyroid to produce T3 and T4.
47
What is ACTH responsible for?
Stimulates adrenal cortex to produce cortisol.
48
What does FSH stimulate?
Egg development in females and sperm production in males.
49
What does LH stimulate?
Ovulation in females and testosterone in males.
50
Which hormones are released from the posterior pituitary?
Oxytocin and ADH.
51
What is oxytocin responsible for?
Uterine contractions and milk ejection.
52
What is the role of ADH?
Promotes water reabsorption in kidneys; low ADH causes dehydration.
53
Where is the thyroid gland located?
Inferior to the larynx with two lobes connected by the isthmus.
54
What are the functions of thyroid hormones?
Regulate metabolism and growth.
55
What hormones does the thyroid produce?
T3, T4, and calcitonin.
56
What does calcitonin do?
Lowers blood calcium levels.
57
What causes goiter?
Excess TSH or thyroid hormone imbalance.
58
Where are the parathyroid glands located?
Posterior surface of the thyroid gland.
59
What hormone do they produce?
Parathyroid hormone (PTH).
60
What does PTH regulate?
Increases blood calcium levels.
61
What condition can chronic PTH overproduction cause?
Osteoporosis.
62
Where are adrenal glands located?
Above each kidney.
63
What are the two parts of the adrenal gland?
Cortex (outer) and Medulla (inner).
64
What hormones are released from the adrenal medulla?
Epinephrine and norepinephrine.
65
What is the function of epinephrine?
Increases heart rate, BP, and energy during stress.
66
What does norepinephrine do?
Constricts blood vessels, increases alertness.
67
What hormone is produced in Zona Glomerulosa?
Aldosterone - regulates salt and water balance.
68
What hormone is produced in Zona Fasciculata?
Cortisol - stress hormone, increases blood sugar.
69
What hormone is produced in Zona Reticularis?
Androgens - sexual development and libido.
70
Where is the pineal gland located?
Roof of the 3rd ventricle in the brain.
71
What hormone does it release?
Melatonin - regulates sleep-wake cycle.
72
Where is the thymus located?
Behind the sternum between the lungs.
73
What hormone does the thymus secrete?
Thymosin - promotes T cell maturation.
74
Where is the pancreas located?
Behind the stomach, near the small intestine.
75
What type of gland is the pancreas?
Mixed - both endocrine and exocrine.
76
What are the pancreatic endocrine cells?
Alpha (glucagon), Beta (insulin), Delta (somatostatin).
77
What does insulin do?
Lowers blood sugar by promoting glucose uptake by cells.
78
What does glucagon do?
Raises blood sugar by promoting glycogen breakdown.
79
What does somatostatin do?
Inhibits insulin and glucagon secretion.
80
What is diabetes mellitus?
A disorder due to insufficient insulin or insulin resistance.
81
What are common symptoms of diabetes?
Hyperglycemia, excessive urination, thirst, fatigue.
82
Difference between Type I and Type II diabetes?
Type I requires insulin injections; Type II may be diet controlled.
83
What are the gonads?
Testes in males and ovaries in females; both reproductive and endocrine.
84
What triggers menstruation?
A drop in progesterone levels.
85
What are major functions of the endocrine system?
Regulates metabolism, growth, water balance, immunity, reproduction, cardiovascular functions.
86
Which hormone regulates metabolism?
T3 and T4 from the thyroid gland.
87
Which hormones affect digestion and intake?
Insulin, glucagon, cortisol.
88
Which hormone regulates salt/water balance?
Aldosterone.
89
Which hormones control reproductive function?
LH, FSH, estrogen, progesterone, testosterone.
90
Which gland modulates immune function?
Thymus via T-cell development.