Endocrine

Question 1

What are the 3 types of congenital adrenal hyperplasia

Answer 1

classical virilising
classical salt wasting
non classical

Question 2

male classical salt wasting symptoms

Answer 2

salt losing crises often occuring with severe 21 hydroxylase deficiency, symptoms include failure to thrive recurrent vomiting, sweating, dehydration, hyponatraemia, hyperkalemia

Question 3

male classic viriliser symptoms

Answer 3

early development of secondary sexual characteristics (pubic hair and phallic enlargement) accelerated growth and increased skeletal maturation

Question 4

female classic salt wasting

Answer 4

ambiguous genitalia, cliteromegaly, fused labia at birth,

Question 5

female classic viriliser:

Answer 5

virilisatio: acne, hirsutism, accelerated growth, increased skeletal maturation

Question 6

17 a hydroxylase deficiency

Answer 6

increased 11 deoxycorticosterone (mineralocorticoid), decreased androgens, males present with ambigous or female genitalia, female present with absence of secondary sexual characteristics at puberty