Endocrine

Question 1

What class is Metformin
MOA

Answer 1

Biguanides

Reduces hepatic gluconeogenesis and increases glucose sensitivity

Question 2

What drug is in class Biguanides

Answer 2

Metformin

Question 3

Mechanism of action for biguanides (metformin)

Answer 3

Reduces hepatic gluconeogenesis and increases glucose sensitivity

Question 4

Side Effects and class of Metformin

Answer 4

Nausea and Vomiting

Interract with diuretics and digoxin

Question 5

What class is Glicazide

Answer 5

Sulphonylureas

Question 6

What drug is in class Sulphonylureas

Answer 6

Glicazides

Question 7

Mechanism of action of Sulphonylureas (Glicazide)

Answer 7

Increases insulin secretion from pancreas

Question 8

Side Effects of Sulphonylureas

Answer 8

Hypoglycaemia

Interacts with warfarin and NSAIDs

Question 9

What class is Pioglitazone

Answer 9

Thiazolidinediones

Question 10

What drug is in class Thiazolidinediones

Answer 10

Pioglitazone

Question 11

MOA of Thiazolidinediones (Pioglitazone)

Answer 11

Increases insulin sensitivity in muscle and adipose tissue

Question 12

Side Effects of Thiazolidinediones (Pioglitazone)

Answer 12

Weight Gain

Question 13

What class is Exenatide

Answer 13

Glucagon-like peptide-1 receptor (GLP-1) agonist

Question 14

What drug is in class Glucagon-like peptide-1 receptor (GLP-1) agonist

Answer 14

Exenatide

Question 15

MOA of Glucagon-like peptide-1 receptor (GLP-1) agonist (exenatide)

Answer 15

Incretin analogue – improves glucose control

Question 16

Side Effects of Glucagon-like peptide-1 receptor (GLP-1) agonist (exenatide)

Answer 16

Asthenia (abnormal physical weakness or lack of energy.)

Question 17

What drug is in class Dipeptidyl peptidase-4 (DPP-4) Inhibitor

Answer 17

Sitagliptin

Question 18

What class is Sitagliptin

Answer 18

Dipeptidyl peptidase-4 (DPP-4) Inhibitor

Question 19

MOA of Dipeptidyl peptidase-4 (DPP-4) Inhibitor (sitagliptin)

Answer 19

Reduces inactivation of incretins

Question 20

Dipeptidyl peptidase-4 (DPP-4) Inhibitor (sitagliptin)

Answer 20

Headache

Question 21

What drug is in class Lipase Inhibitor

Answer 21

Orlistat

Question 22

What Class is Orlistat

Answer 22

Lipase Inhibitor

Question 23

MOA of Lipase Inhibitor Orlistat

Answer 23

Inhibition of GI uptake of dietary fats

Question 24

Side Effects of Lipase Inhibitor Orlistat

Answer 24

Oily Stool, Faecal Urgency

Question 25

Name a blood glucose reducing hormone

Answer 25

Insulin

Question 26

What is insulin

Answer 26

a blood glucose reducing hormone

Question 27

side effects of medical insulin

Answer 27

Hypoglygaemia Interacts with digoxin and beta-blockers

Question 28

How does blood glucose reducing hormone, Insulin, work

Answer 28

Stimulation of glucose uptake by cells

Question 29

Name some thyroid hormones

Answer 29

``` Levothyroxine Sodium (T4) Liothyronine Sodium (T3) ```

Question 30

``` What are Levothyroxine Sodium (T4) and Liothyronine Sodium (T3) ```

Answer 30

Thyroid Hormones

Question 31

``` Side Effects of Thyroid Hormones Levothyroxine Sodium (T4) and Liothyronine Sodium (T3) ```

Answer 31

Diarrhoes, Vomiting Interact with oral anti-coagulants

Question 32

``` MOA of Levothyroxine Sodium (T4) and Liothyronine Sodium (T3) ```

Answer 32

Synthetic Hormones