Endocrine and Cardiovascular Lab Flashcards
(38 cards)
What is released from Heart when its damaged
Protein and Enzyme
Hypopituitarism
- Kind of condition
- Lab Values
Adrenal Insufficiency
- Pituitary gland dont release CRH
Low ACTH
Low Cortisol
Adrenal Lab Values and Time of Day
Reference values depend on the time of day
Cushing’s Disease (Pituitary Adenoma)
- Kind of condition
- Lab Values
High ACTH
High Cortisol
3 Types of Lipids
Cholesterol (Major building resource - Cell membranes, hormones)
- Marker of heart disease
Triglycerides (Energy Source)
- Muscles
Phospholipids (make up all cell membrane)
Hyperthyroidism (8)
- Symptoms
- Weight Loss
- Heat Intolerance
- Palpitations
- Tremors
- Nervousness
- Sweating
- Muscle Weakness
- Goiter
Hypothyroidism (6)
- Symptoms
- Weight Gain
- Dry Skin
- Cold Intolerance
- Constipation
- Menstrual Irregularities
- Fatigue
Cushing’s Disease
(Adrenal Adenoma)
Low ACTH
High Cortisol
Clotting Cascade Pathways
Intrinsic and Extrinsic paths
- Leads to two different kinds of lab values
Oral Glucose Tolerance Test
Sample taken 2 hours after 75 gm glucose load
Hypothyroidism Lab Values
High TSH
Low T4
Random Blood Glucose
Sample from Nonfasting state
Hemoglobin A1c
Average blood glucose levels over last 2-3 months
Lipid Flagging Limits
- Total Cholesterol
- HDL
- Literally Everything Else
- Should be low
- Should be high
- Should be low
INR: PT / Control
High = Clots too slow
Low = Clots too fast
Cardiac Injury Lab Values
Cardiac Proteins
- Troponin I, High Sense
- Troponin T, High Sense
Cardiac Kinase
- Creatine Kinase MB
Prothrombin Time
How long it takes for blood to clot
- Helps access liver function
- Measures more factors than PTT
Extrinsic
Fasting Blood Glucose
No food consumed in last 8 hours
Partial Thromboplastin Time
Measure how long it takes for blood to clot
Used to monitor effects of unfractionated heparin
Intrinsic (Excludes Factor VII and XIII)
- Measures less factors than PT
Adrenal Excess
- Symptoms
- Weight Gain
- Redistribution of Fat
- Hypertension
- Hirsutism
Cushing’s DIsease
(Excess Glucocorticoid Steroid Use)
Low ACTH
Low Cortisol
Coagulation Process
Platelet Activation
- Forms a plug
Fibrin Formation
- Platelet release clotting factors, creates fibrin, stabilizes plug, creates insoluble clot
Causes of Creatine Kinase Increase
Skeletal
- Vigorous Exercise, Trauma, Rhabdomyolysis
Cardiac
- Myocarditis, Acute Myocardial Infarction
Drugs that affect thyroid function (7)
Lithium
Amiodarone
Carbamazepine
Corticosteroids
Oral Contraceptives
Phenytoin
Propranolol
