Endocrine and Metabolic Disorders Flashcards

(47 cards)

1
Q

Definition of Gestational Diabetes

A

any degree of glucose intolerance with onset or recognition during pregnancy (due to the body dealing with the baby)

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2
Q

What is the risk factors of Diabetes type 2

A

Obesity, Aging, Sedentary lifestyle, HTN, and prior gestational diabetes

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3
Q

What is White Classification of GDM: GOOD

A

A-C

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4
Q

What is White’s classification of GDM: vascular complications

A

D F R T

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5
Q

Insulin Requirement during the1st trimester

A

Insulin production increased -> peripheral use of insulin -> results in decreased blood glucose
NV (hypergravidemism) drop in mother’s glucose
HPL (human placental lactogen) is secreted = insulin antagonist

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6
Q

Insulin Requirements in 2nd and 3rd trimesters

A

Insulin requirement ^ 4x
abrupt drop of hormones and return to prepregnant state
- Insulin needs decrease

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7
Q

Maternal Risks of Complication GDM

A

Worsening of pre-existing disease -> vascular problems -> retinopathy
Hypoglycemia 1st half of pregnancy
Hyperglycemia -> ketoacidosis 2-3rd trimesters
Preeclampsia and eclampsia
Polyhydramnios in 10-20% of diabetic
Dystocia *C-section

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8
Q

When does the baby pancreas create it own insulin

A

10 wks gestation

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9
Q

Effects on fetal GDM (most common)

A

Macrosomia r/t excess glucose from Mom
Large for gestational age (LGA) >4000g

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10
Q

More effects on fetal GDM

A

IUGR= maternal vascular involvement
Delayed lung maturity -> respiratory distress syndrome
Hypoglycemia after birth
Congenital anomalies (NTD and SD)

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11
Q

Read slide about screening and testing for GDM

A
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12
Q

Values of OGGT (Testing for Diabetes)

A

FBS <95 mg/dl
1 hr <180mg/dl
2 hr <155 mg/dl
3 hr <140 mg/dl

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13
Q

What is the management of DM during pregnancy

A

Insulin therapy, exercise, glucose monitoring, diet

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14
Q

What should be the target range for Premeal/Fasting (Managing Glucose)

A

> 65 mg/dL but <105 mg/dl

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15
Q

What is the recommended meals and snacks for a GDM

A

3 meals and 2-3 snacks

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16
Q

How much carbo should the pt intake?

A

no more than 55%

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17
Q

For a night snack, what should be recommended

A

protein and at least 25g complex carb

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18
Q

Do you need foods before taking insulin

A

YES

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19
Q

Exercise GDM

A

30-60 mins walking or swimming a day
10-20 mins period throughout the day
Snack of protein or complex CHO before exercise
Monitor glucose before and after

20
Q

Insulin therapy

A

2/3 of daily insulin at breakfast -> combination of intermediate or long acting and shorting acting insulin
1/3 of daily insulin in the evening -> combination of long-acting and short-acting insulin

21
Q

Risk Factors of Hypoglycemia

A

Too little food
Too large insulin dose
Stress= ^ sugar
Illness/Vomiting or diarrhea
Exercise

22
Q

Symptoms of Hypoglycemia

A

Nervousness
HA
Shaking/irritable
Hunger
blurred vision
Diaphoresis

23
Q

Treatment of Hypoglycemia

A

Check blood glucose
<70 mg/dL eat or drink 8-16g of Cho (hard candy, skim milk, unsweetened OJ, soda
Rest 15 mins -> recheck glucose
Notify caregiver if continues
If it is greater, provide a meal with protein

24
Q

Signs and Symptoms Hyperglycemia

A

Glucose >130 mg/dl
Ketones in urine
Dry and flushed skin
Polyuria, polydipsia
Kussmaul respirations *regular insulin
DKA-medical emergency

25
Fetal Surveillance
MSAFP @ 15-20 wk gestation Biophysical Profile Fetal echocardiogram NST 1x2x weekly from 34 weeks gestation FM (kick) daily 28th wk Ultrasound for anomalies
26
Reasons for earlier delivery
IUGR Hypertensive disorder getting worse Macrosomia Poor metabolic control
27
Diabetes during Labor and Delivery
Fluids and insulin titrated to maintain glucose <140 Hourly glucose check Regular insulin infusing piggyback into IV
28
Second Stage of Labor
Voluntary pushing required the mother to use a lot of energy -> glucose checks more frequently Failure to Progress: Shoulder dystocia and CPD (Cephalopelvic Disproportion)
29
Postpartum w/ glucose
Insulin requirement decrease w/ removal of placenta and insulin antagonists
30
What help with stabilize diabetes
Breast feeding
31
Infant Symptoms of Diabetic Mother
Jittery Apnea Tachypnea Cyanosis Hypotonia Unstable temperature
32
What is normal range of glucose for a infant
40-45 mg/dL
33
Risk Factors for GDM
Family hx of diabetes Ethnic group at risk (native american) Maternal obesity Previous LGA Previous unexplained stillbirth
34
Postmeal (1hr) Glucose Monitoring (Target Goal)
<140 mg/dL
35
Postmeal (2hr) Glucose Monitoring (Target Goal)
<= 120 mg/dl
36
2 am- 6 am Glucose Monitoring (Target Goal)
lowest drop >60 mg/dl
37
Non obese Diet Management Calories
35 cal/kg/IBW/day
38
Obese Diet Management Calories
25 kg/IBW/day
39
Etiology of Hyperemesis
^ level of HCG or estrogen Hyperthyroidism during pregnancy Esophageal reflux Psychosocial factors
40
Clinical symptoms Hyperemesis
Inability to retain even clear liquid Weight lose >5% Dehydration Starvation Electrolyte imbalance (Na+, Cl-, K+)
41
Fetal Risk of Hyperemesis
IUGR (due to not getting enough) Abnormal development Preterm Birth (uterus= smooth muscle) SGA Death from lack of nutrition, hypoxia, maternal ketoacidosis
42
Medications for Hyperemesis
Pyridoxin (B6) w/w/o doxylamine Vesprin Phenergan Zofran Reglan Nexium Steroid Therapy Enteral or parental nutrition
43
Phenylketonuria
Deficiency in enzyme phenylalanine hydrolase
44
What does phenylketonuria interferes
Brain development
45
Maternal phenylketonuria should remain
less than 6 mg/dL before conception and remain <2 mg/dl during pregnancy
46
What does the glucose need to be for Oral glucose tolerance test for them to need follow up for the 3 hr
130-140
47
What is normal glucose level
70-100 mg/dl