Endocrine disease Flashcards
(9 cards)
1
Q
What binds to surface receptors?
A
Peptides(charged)
2
Q
What binds to nuclear receptors
A
Steroid(aliphatic)
3
Q
Law of mass action>
A
4
Q
How is the levels of hormone measured?
A
Standard curve
5
Q
What are the two types of hormone assays?
A
Total hormone assays (cheap+easy) bound to proteins)
Free hormone assays( not bound to proteins)
6
Q
Free hormone assays?
Pros+cons
A
*representative of active hormone
* not binding proteins dependant
* complex + expensive + seperation steps
* poor reproducibility
7
Q
How can thyroid nodule be diagnosed?
A
-ultrasound
-FNA
-CT neck
8
Q
How can goitre be diagnosed?
A
- thyroid function
- ultrasound
- CXR
- CT MRI
- flow volume loop
9
Q
Tests for cushings?
A
- urinary free cortisol
- diurnal rhythm
- over night dexamethasone supression testing
