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Flashcards in Endocrine Drugs Deck (2)
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1
Q

Describe the mechanism of action of metformin.

A
  1. Increases activity of AMP-dependent protein kinase (AMPK)
    a. This inhibits gluconeogenesis
  2. Also reduces insulin resistance
2
Q

What are the 3 main types of drug you can use to treat type 2 diabetes?

Give an example of each.

A

Biguanides (e.g. Metformin)
Sulphonylureas (e.g. Gliclazide)
GLP1 agonists (e.g. Liraglutide)