Endocrine Glands And Hormones Flashcards
(24 cards)
What does the hypothalamus control and where is it found
found in the brain (above the brainstem)
controls, hormones, homeostasis and also thermoregulation, circadian rhythms
How does the hypothalamus control thermoregulation
controlled via thermoreceptors in the hypothalamus that compare the current temp with a set point
any increase or decrease sees effectors such as muscles and glands work to counteract the change
What lobe of the pituitary produces and secretes its own hormones in response to releasing hormones from the hypothalamus
anterior lobe
How do hormones travel from the hypothalamus to the anterior pituitary
via blood vessels known as hypothalmic- pituitary portal vessels
how do hormones travel from the hypothalamus to the posterior pituitary
along nerve axons
What is a common method of regulation used in hypothalamus hormones
negative feedback inhibition
What is the main function of the thyroid hormone
to regulate metabolism
where is the thyroid gland located
neck, just below adams apple
what hormones does the thyroid gland produce
thyroid hormones ( t3 and t4 (thyroxine)) - influence metabolic rate calcitonin - acts to decrease blood calcium levels
what cells produce the thyroid hormones
follicular cells of the thyroid gland
simple goitre
swelling of thyroid gland
how many parathyroid glands are there
in majority of people - 4
where are the parathyroid glands found
on the internal surface of the thyroid gland
what is produced by the parathyroid glands
parathyroid hormones which regulate blood calcium levels
when is insulin released and what is its function
released in response to raised blood glucose and acts to lower it
when is glucagon released and what is its function
released in response to low blood glucose and acts to raise blood glucose by breaking down glycogen and fat etc
glycogen in humans
acts as energy storage
where are the adrenal glands found
lie on top of the kidneys
what is produced in the adrenal glands
cortex hormones - cortisol, aldosterone, androgens
cortisol
glucocorticoid that has metabolic effects and activates anti-stress and anti-inflammatory pathways
aldosterone
mineralocorticoid - release controlled by RAAS. regulates BP by promoting reabsorption of Na and H2O
describe the renin-angiotensin-aldosterone system
1 - liver produces angiotensiogen
2 - in response to low fluid volume, kidneys produce renin which converts angiotensinogen to angiotensin 1
3 - this is further converted by enzyme ACE to angiotensin 2
4 - this acts on the adrenal glands and stimulates aldosterone release
5 - aldoesterone acts on kidneys and causes water retention increasing fluid volume and therefore BP
androgens
gonadocorticoids
contribute to pubertal growth and sexual characteristics
addisons disease
very serious condition where the adrenal glands are damaged and dont produce enough cortisol or aldosterone