Endocrine Metabolism Flashcards
(29 cards)
(2) organs that control the body’s fuel supply
liver & endocrine pancreas
liver regulates blood glucose via (3)
glycogenesis
glycogenolysis
gluconeogenesis
glycogenesis:
glucose converts to glycogen (stored)
glycogenolysis:
glycogen converting to glucose (body needs it, liver releases it)
gluconeogenesis:
breakdown of non-carbohydrate substances into glucose (ie. protein into AAs)
fats
liver converts excess fat into ketones and releases them into the blood; in situations that favour fat breakdown, excess ketones in the blood cause ketoacidosis
proteins
broken down into AAs; proteins can be used for gluconeogenesis when metabolic needs exceed food intake
pancreas: acini cells
secrete digestive juices into the duodenum
pancreas: islets of langerhans
secrete 3 hormones that regulate blood glucose levels
pancreas: alpha cells secrete
glucagons
pancreas: beta cells secrete
insulin
pancreas: delta cells secrete
somatostatin
close proximity permits
coordination (ie. insulin inhibits glucagon release and somatostatin ibhibits both insulin and glucagon release
transports and metabolizes glucose for energy
beta cells
stimualtes storage of lucose in the liver&muscles
beta
signals liver to stop the release of glucose
beta
enhances storage of dietary fat in adipose tissue
beta
accelerates transport of AAs (from dietary protein) into cells
beta
inhibits breakdown of stored glucose/protein/fat
beta
released after carb ingestion
insulin (3-5 min peak)
binds to cell receptors/receptors on the surface of target tissues
insulin
decreases blood glucose
insulin
enhances AA transport into cells
insulin
acts with growth hormone to promote cell hypertrophy and hyperplasia
insulin