Endocrine Part 2 Miliotic Flashcards
are hydrophilic hormones water soluble?
yes
what happens when water-soluble hormones reach the plasma?
Dissolve in plasma
can hydrophilic hormones cross the plasma membrane?
no
what are examples of hydrophilic hormones?
Peptide hormones, protein hormones, catecholamines
what are examples of hydrophobic hormones?
Steroid hormones, thyroid hormones
are hydrophobic hormones water soluble?
Not water-soluble
can hydrophobic hormones freely cross the plasma membrane, why or why not?
Lipid-soluble, cross-plasma membranes
what are steroid hormones made from?
Made from cholesterol
How are peptide/protein hormones synthesized and released?
Made in advance
Stored in vesicles
Released by exocytosis
how are steroid hormones made?
Synthesized on demand
how are steroid hormones released?
Released by diffusion
What are amine hormones derived from?
Tryptophan or Tyrosine
what are examples of amine hormones and what amino acid are they derived from?
Melatonin from tryptophan, Catecholamines from tyrosine, Thyroid hormones
How do peptide/protein hormones travel in the blood and what do they bind to?
Dissolved in plasma
Bind to membrane receptors
what is the half-life of peptide/protein hormones?
short
How do steroid hormones travel and enter cells?
Bound to carrier proteins
Diffuse into cells or taken up by endocytosis
what is the half-life of steroid hormones?
long
What stimuli triggers hormone release?
Metabolites (e.g., glucose)
Neurohormones
Neurotransmitters
What is the process of synergistic effects in hormones?
Multiple hormones act together for a greater effect
what is an example of synergistic effects?
FSH and testosterone on sperm production
What is the process of permissive effects in hormones?
One hormone enhances an organ’s response to a later hormone
what is an example of permissive effects?
Estrogen prepares the uterus for progesterone
What is the process of antagonistic effects in hormones?
One hormone opposes another
what is an example of antagonistic effects?
Insulin lowers blood glucose, glucagon raises it