Endocrine & Reproductive Flashcards
(212 cards)
What hormones are involved in growth?
- Pituitary growth hormone.
- Thyroid hormone.
- Testosterone.
- Estrogen.
- gonadotropic
What happens to hormone production as we age?
- Some target tissues become less sensitive to their controlling hormone
- The pituitary gland gradually shrinks in size.
- Metabolism slows.
- In women, the amount of TSH produced does not decrease with time, but it does in men.
- With aging, men sometimes experience a slightly decreased level of testosterone.
- Women have decreased levels of estradiol and estrogen after menopause.
- Levels of growth hormones decrease.
What is the difference between a secondary oocyte and an ovum?
An ovum is a fertilized oocyte, while a secondary oocyte is an oocyte that is ready to be ovulated and fertilized.
The process by which oocytes (and follicles) perish without having been expelled by ovulation. Only about 400 oocytes ovulate - about 99.9 % of the oocytes that where present at the time of puberty undergo this process. This may effect oocytes at all stages of their “life” - both prenatally and postnatally. By the sixth month of gestation about 7 million oocytes and oogonia are present in the ovaries. By the time of birth this number is reduced to about 2 million. Of these only about 400.000 survive until puberty.
Atresia.
describe the functional anatomy of a spermatozoa.
Head: the top portion of the sperm
Neck: attaches the head to the middle piece. Contains both centrioles of the original spermatid.
Mid Piece: The microtubules of the distal centriole are continuous with those of the middle piece and tail.
Mitochondria in the middle piece are arranged in a spiral around the microtubules. Mitochondrial activity provides the ATP required to move the tail.
Tail: the only flagellum in the human body. Moves the sperm from one place to another.
Adult sperm cell.
Spermatozoa / Spermatozoon.
The activation process that must occur before a spermatozoon can successfully fertilize an oocyte.
Capacitation.
describe the events that lead to capacitation.
1) Sperm become motile when they are mixed with secretions of the seminal glands
2) Sperm become capable of successful fertilization when exposed to conditions in the female reproductive tract
where in the female system should fertilization occur?
The ovaries produce the female egg cells, called the ova or oocytes. The oocytes are then transported to the fallopian tube where fertilization by a sperm may occur. The fertilized egg then moves to the uterus, where the uterine lining has thickened in response to the normal hormones of the reproductive cycle.
describe the relationship between the ovarian and the uterine cycle.
If the ovarian and uterine cycles do not occur in perfect timing, fertlization of a secondary oocyte would never be possible - leading to infertility. Asa primary follicle becomes a secondary follicle within the ovary, estrogen will tell the endometrium to thicken within the uterus in preparation for the implantation of a fetilized egg. After ovulation has occured, the courpus luteum will secrete progesterone and low levels of estrogen, which will then tell the uterine wall to thicken further in preperation of implantation.
list and explain the three physiological phases of male sexual response.
- Arousal: erotic thoughts or stimulation of sensory nerves in the genitial regions leads to an increase in the parasympathetic outflow over the pelvic nerves. Blood flow is increased, which causes an erection. Arousal also stimulates the bulbourethral glands, and their secretion lubricates the tip of the penis.
- Emission: Further stimulation leads to a sympthatic activation that causes emission. Emission begins with peristaltic contractions of the ductus deferens, which pushes spermatozoa into the prostatic urethra. Secretions from the seminal and prostate glands enter the urethra and mix with the spermatozoa to form semen.
- Ejaculation: Ejaculation occurs as powerful contractions take place in the bulbocavernous muscles - these muscles wrap around the base of the penis and their contractions push semen towards the external urethral orifice.
Be able to trace spermatozoa through the ductal pathways from the epididymis to the external urethral orifice.
Remember: SEVEN UP!! S- Seminiferous tubules E- Epididymis V- Vas deferens E- Ejaculatory duct N- NOTHING (just here to help us remember SEVEN UP) U- Urethra P- Penis
Be able to contrast down-regulation with up-regulation and give an example of each.
Up-regulation: increases the # of receptors in response to a decreased hormone level.
Down regulation: decreases the # of receptors in response to a decreased hormone level.
Be able to list the 3 phase of stress and indicate which hormones play a role in each stage.
- The alarm stage: What is the alarm stage? Your body releases a substance called epinephrine. It causes many immidiate changes in your body. Your heart beats faster, your breathing speeds up, and your muscles tense. Your attention narrows as you focus on the stressor
- the resistance stage: if the stress lasts longer than a few hours, a person will enter the resistance stage. Glucocorticoids are the dominant hormones in this phase. The demand for energy is still higher than normal. Glycogen reserves are adequate to maintain normal glucose levels during the alarm phase but are nearly exhausted after several hours. The hormones of this phase mobilize lipids and amino acids to shift tissue metabolism away from glucose so that it may be used by neural tissues.
- the exhaustion stage: it is at this point that the body is running off of lipid reserves, but this cannot be maintained indefinitely. It is at this point that the systems of the body will begin to shut down, which may lead to death if not treated quickly enough.
Be able to explain when spermatogenesis begins and ends in male life span and how many spermatozoa can be produced.
Begins: puberty.
Ends: death.
About 500 billion can be produced in a lifetime.
Be able to describe when oogenesis begins and ends in the female life span and how many secondary oocytes can be produced.
Oogenesis begins before birth, and ends with menopause. During this timespan, a woman will, on average, release about 400 secondary oocytes.
Where does oogenesis occur?
The ovaries.
Intercellular communication through gap junctions.
Direct communication.
Intercellular communication through exocrine communication.
Paracrine communication.
Intercellular communication through the bloodstream.
Endocrine communication.
Intercellular communication across synapses.
Synaptic communication.
What are the most common pathophysiology conditions of Diabetes Mellitus I?
Inadequate insulin production by the pancreatic beta cells.
What are the most common pathophysiology conditions of Diabetes Mellitus II?
Insulin resistence - the tissues do not respond properly to insulin found in the bloodstream. Most often associated with obesity.
derived from cholesterol and produced by the adrenal gland, the gonads, and the placenta. In general, they are synthesized as they are needed and are not stored to any great extent. They are lipid soluble and circulate bound to a carrier protein.
Steroid.