Endocrine System Flashcards

1
Q

Exocrine Gland

A

Secrete their contents through tubes or ducts onto an interior or exterior body surface e.g sweat

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2
Q

Endocrine Gland

A

(Ductless) glands secrete hormones directly into the blood stream, which delivers to specific target cells or tissues

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3
Q

Hormone

A

A chemical messenger that is secrete by an endocrine gland, often carried in blood.

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4
Q

Target Organ

A

Particular organs that a hormone targets

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5
Q

Paracrine

A

Cells that communicate with other cells in the same tissue by secreting chemicals that diffuse to adjacent cells.

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6
Q

Hypothalamus

A

Located in the brain

Secretes hormones that regulate the pituitary gland

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7
Q

Pituitary gland

A

Located in the brain
2 lobes posterior and anterior
Secretes hormones that control the function of the other glands in endocrine system

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8
Q

Anterior Pituitary hormones

A
  • Adrenocorticotrophic hormone
  • growth hormone
  • luteinising hormone
  • follicle stimulating hormone
  • prolactin
  • thyroid stimulating hormone
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9
Q

Adrenocorticotrophic Hormone

A

Stimulates adrenal glands to produce hormones

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10
Q

Growth Hormone

A

Regulates body growth

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11
Q

Luteinising Hormone

A

Acts on ovaries to stimulate oestrogen production and testes to stimulate testosterone production

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12
Q

Follicle stimulating hormone

A

Causes maturation of egg and sperm

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13
Q

Prolactin

A

Produces milk in mammory glands of breasts

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14
Q

Thyroid stimulating hormone

A

Stimulates the production and release of hormones from thyroid gland

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15
Q

Posterior Pituitary Hormones

A

Antidiuretic hormone

Oxytocin

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16
Q

Anti diuretic hormone

A

Increases water reabsorption in the nephron

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17
Q

Oxytocin

A

Stimulates contractions in childbirth and contraction of the lobules in the breast for lactation

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18
Q

Thyroid Gland

A

Located in the neck

Produces thyroxine which increases cellular metabolism

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19
Q

Parathyroid Glands

A

Four small glands at back of thyroid gland

Produces parathyroid hormone which controls calcium metabolism

20
Q

Pancreas

A

Has both exocrine and endocrine glands
Releases pancreatic juices into duodenum
Releases insulin and glucagon into bloodstream

21
Q

Thymus

A

Located above heart
Produces thymosins
Involved in maturation of white blood cells

22
Q

Gonads

A

Ovaries produce oestrogen and progesterone

Testes produce testosterone

23
Q

Pineal Gland

A

Located in the brain

Produces melatonin which regulates day/night response

24
Q

Adrenal Medulla

A

Adrenal glands are located on top of kidneys, medulla in the middle
Produces adrenaline and noradrenaline
Involved in sympathetic stimulation of the nervous system

25
Adrenal cortex
Outer layer of adrenal glands
26
Hypothalamus Partnership
Interprets nerve impulses and converts them into chemical messages that regulate the secretion of hormones from pituitary gland
27
Hypothalamus Functions
Regulation of pituitary gland Production of hormones Regulation of temperature Regulation of the autonomic nervous system Regulation of emotions and sexual behaviour
28
Anterior Lobe
Responds to factors released from the hypothalamus and produces a variety of hormones
29
Hormones
Chemical messengers secreted by endocrine glands. Can affect cells or organs. Receptorcides required
30
Hormones affects on cellular activity
Change the permeability of cell membrane | Change the rate of chemical reactions which occur in the cell
31
Hormones affects on proteins
Change shape and structure of enzyme | Change rate of transcription/translation of proteins
32
Steroid Hormones
Enter through plasma membrane into cytoplasm Stimulates or inhibits particular protein synthesis Fat soluble hormones e.g testosterone and cortisol
33
Protein/Amine Hormones
Activate specific receptors on the plasma membrane cannot pass through Secondary messenger diffuses into cell Protein and amine hormones are water soluble Inhibit or stimulate particular enzymes E.g oxytocin and insulin
34
Diabetes
Diabetes is a disease that affects your body’s ability to produce or use insulin
35
Diabetes causes
``` Type 2: Genetics Lifestyle Unhealthy diet Obesity Lack of exercise Type 1: autoimmune response- body’s immune system attacks and destroys insulin producing beta cells in the pancreas ```
36
Diabetes symptoms
``` Extreme thirst Frequent urination Blurry vision Extreme hunger Fatigue Unusual weight loss ```
37
Diabetes treatment
Aim of treatment is to keep low blood glucose levels as close to normal as possible People with diabetes need to monitor blood glucose levels regularly Type 1: treated with insulin replacement through insulin injections, healthy diet and regular exercise Type 2: lifestyle modification (healthy diet, regular exercise and weight loss) and oral medications to control blood glucose levels
38
Hyperthyroidism
Hyperthyroidism (sometimes called thyrotoxicosis) occurs when the thyroid gland is overactive.
39
Hyperthyroidism causes
The most common cause of hyperthyroidism in Australia is Graves’ Disease, an autoimmune condition where the immune system stimulates the thyroid to produce too much hormone. Hyperthyroidism can also be caused by the thyroid becoming inflamed (thyroiditis) or by nodules inside the thyroid which become hyperactive.
40
Hyperthyroidism symptoms
Feel overly anxious  Feeling overly tied Losing weight despite same lifestyle (Graves’ Disease) Unable to tolerate heat Bulging Eyes (Graves’ Disease) Enlarged Thyroid or Goiter (Graves’ Disease)
41
Hyperthyroidism treatment
Medicine can be used to reduce the amount of hormone produced by thyroid Radioactive iodine therapy which shrinks the thyroid Could be removed by surgery this may lead to damage to surrounding nerves and surrounding glands.
42
Aldosterone
controls sodium levels | Adrenal cortex
43
Cortisol
involved in stress response | Produced in adrenal cortex
44
Hypothyroidism
Where the thyroid gland does not produce enough thyroxine | Slows down cell metabolism
45
Hypothyroidism causes
Autoimmune disease known as hashimotos thyroiditis | Radiation therapy
46
Hypothyroidism symptoms
``` Fatigue Weight gain Sensitivity to cold Depression Muscle weakness pain/stiffness in joints Impaired memory ```
47
Hypothyroidism treatment
Diagnosed with blood test- symptoms may not occur Prescribed hormone tablets called levothyroxine Combination therapy