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Med physiology Quiz 3 > Endocrinology > Flashcards

Flashcards in Endocrinology Deck (24)
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1

Hyposecretion

The secretion of too little hormone

2

Hypersecretion

The secretion of too much hormone

3

Hyporesponsiveness

Occurs when the receptors on target cells are under-responsive to a hormone

4

Hyperresponsiveness

Occurs when the target cells over respond to a hormone

5

Primary Disorder

The disorder is located primarily in the end-organ

6

What is an example of a primary disorder?

Primary hyperthyroidism - under production of the thyroid hormone, which happens because of problems in the thyroid itself

7

Secondary Disorder

The source of the disorder is somewhere besides the end-organ

8

What two glands are usually involved in a secondary disorder?

Hypothalamus or pituitary

9

What is an example of a secondary disorder?

Secondary hypercortisolism - a pituitary tumor makes makes too much ACTH, causing the adrenal gland to make too much cortisol

10

What is a tropic hormone?

A hormone whose purpose is to release another hormone

11

In a patient with hyperthyroidism, what would you expect to happen to the levels of T3, T4, and TSH? (would they be higher than normal, normal, or lower than normal?

T3 - higher than normal
T4 - higher than normal
TSH - lower than normal

12

Which gland sits in the anterior neck and consists mainly of follicles; it also contains colloid

The thyroid gland

13

Which cells of the thyroid secrete calcitonin?

C cells

14

How many parathyroid glands are there, and where are they located?

4; posterior surface of the thyroid

15

The actual thyroid hormone is secreted where?

Within the colloid space

16

The 3 and 4 of T3 and T4 refer to what?

The number of Iodide groups

17

Which thyroid hormone is more active, T3 or T4?

T3; T4 can actually covert to T3 when levels are low

18

The general term for any situation in which plasma levels of cortisol are chronically lower than normal

Adrenal insufficiency

19

Patients with adrenal insufficiency suffer from what type of symptoms

Weakness, lethargy, loss of appetite

20

Why might patients with an adrenal insufficiency suffer from low blood pressure?

Because cortisol is needed to permit the full extent of the cardiovascular actions of epinephrine

21

A decrease in aldosterone concentration can cause what problem?

An imbalance of Na+, K+, and water

22

What disease is caused by too much cortisol in the blood?

Cushing's syndrome

23

How does Secondary Cushing's syndrome (Cushing's disease) present?

Uncontrolled catabolism of bone, muscle, skin and other organs

24

What are symptoms of Cushing's syndrome?

Osteoporosis, muscle weakness, blood sugar rises to diabetic levels, immunosuppression, redistribution of fat, and hypertension