EndoCRYYYYYne Flashcards

(37 cards)

1
Q

Prednisone

A

synthetic GCC, pretty much fake cortisol anti-inflam, immune suppression, adrenocortial insufficiency - GCC excess

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2
Q

Fludrocortisone

A

Fake mineralcorticoid aldosterone mimic

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3
Q

Cosyntropin

A

ACTH faker use the diagnose adrenal insufficency

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4
Q

Beclomethsone

A

Synthetic GCC anti-inflam used for ASTHMA AND ALLERGIC RHINITIS

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5
Q

Estrogen

A

estrogen! inhibit FSh and LH to decrease ovulation OCP - Endometrial Ca, Breast CA, TEE

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6
Q

Diethylstilbestrol–DES

A

pseudo estrogen sucks: vaginal and cervical clear cell adenocarcinoma

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7
Q

Clomiphene

A

SERM Antagonist at hypothalamus: increase GnRH/FSH/LH Agonist at ovaries Rx: infertility -: too many babies!

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8
Q

Tamoxifen

A

SERM Antagonist for boobies! Agonist for bone. Breast cancer drug - Hot flash, endometrial cancer, VTEE

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9
Q

Raloxifene

A

SERM he does what tamoxifen does without the endometrial cancer risk

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10
Q

Anastrozole

A

inhibitor of aromatse Androgen stopper treat ER positive Breast CA - Arthralgias, myalgias

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11
Q

Progestin

A

Pseudo Progesterone rx: contraception prevent endometrial maturation, decrease uterine and tubal motility HRT DUB–stop bleed due to constant estrogen without progesterone Endometriosis–prevent proliferation of ectopic endometrial tissue

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12
Q

Testosterone

A

Testosterone make you a man! rx: hypogonad -: acne and being michael phelps

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13
Q

Flutamide

A

Anti-androgen competitive antagonist for androgen receptor rx: prorstate cancer

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14
Q

Finasteride

A

5a reductase inhibtor block conversion of T–>DHT rx: BPH and balding

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15
Q

Leuprolide

A

Fake GnRH intermittently: stimulate FSh and LH contiuously (on loop) inhibit FSH and LH RX: infertility and prostate cancer

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16
Q

Octreotide

A

Fake somatostatin decrease GI blood flow rx: esophageal variceal bleed

17
Q

Oxytocin

A

Induce uterine contractions induction of labor

18
Q

Vasopression

A

ADH doppleganger increase water abs RX: DI and vasodilatory shock

19
Q

Desmopressin

A

long acting ADH doppleganger RX: DI

20
Q

Levothyroxine

A

Fake thyroid hormone upregulate metabolism and energy expenditure rx: hypothyroid

21
Q

Methimazole

A

inhibit theyroid peroixidse decrease the production of T3/T4 RX: Hyperthyroidism - agranulocyotis aplastic anemia allergy

22
Q

Proypylthiouracil

A

PTU Peripheral thyroid utilizer stoper Stop perpipheral conversion of thyroid hormone Hyperthyroid

23
Q

Insulin

A

insulin ctronol glucose in diabettes - hypoglycemia

24
Q

Glyburide

A

Sulfonylurea enhace insulin release from B islet cells DM II

25
Nateglinide
inhance insulin release from B islet cell facilitate early meal mediated insulin secretion DMII
26
Exenatide
GLP doppleganger promote insulin synthesis and secretion DMII
27
Metformin
Decrease hepatic GNG DMII
28
Rosiglitazone
insulin sensitizer via PArry DMII - hepatotoxic
29
Acarbose
a glucosidase inhibitor delay intestinal abse of carbs DMII
30
Atoravastatin
block endogenous cholesterol synthesis reduce hypercholestertemia
31
Gemfibrozil
increase liprotein lipase activity Decrease TG, increase HDL, decrease LDL HyperTG
32
Niacin
decrease hepatic synthesis of TG RX: hyper TG - flush
33
Cholestryamine
disrupt bile acid recycling decease cholesterol, LDL and increase HDL and TG
34
Ezetimibe
inhibit intestinal cholesterol absoprtion rx: hypercholesterolemia
35
Alendronate
rx osteoporosis
36
Teriparatide
fake PTH treat osteopoosis
37
Cinacalcet
mimic bone CA treat hyper PTH