EndoCRYYYYYne Flashcards

1
Q

Prednisone

A

synthetic GCC, pretty much fake cortisol anti-inflam, immune suppression, adrenocortial insufficiency - GCC excess

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2
Q

Fludrocortisone

A

Fake mineralcorticoid aldosterone mimic

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3
Q

Cosyntropin

A

ACTH faker use the diagnose adrenal insufficency

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4
Q

Beclomethsone

A

Synthetic GCC anti-inflam used for ASTHMA AND ALLERGIC RHINITIS

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5
Q

Estrogen

A

estrogen! inhibit FSh and LH to decrease ovulation OCP - Endometrial Ca, Breast CA, TEE

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6
Q

Diethylstilbestrol–DES

A

pseudo estrogen sucks: vaginal and cervical clear cell adenocarcinoma

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7
Q

Clomiphene

A

SERM Antagonist at hypothalamus: increase GnRH/FSH/LH Agonist at ovaries Rx: infertility -: too many babies!

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8
Q

Tamoxifen

A

SERM Antagonist for boobies! Agonist for bone. Breast cancer drug - Hot flash, endometrial cancer, VTEE

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9
Q

Raloxifene

A

SERM he does what tamoxifen does without the endometrial cancer risk

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10
Q

Anastrozole

A

inhibitor of aromatse Androgen stopper treat ER positive Breast CA - Arthralgias, myalgias

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11
Q

Progestin

A

Pseudo Progesterone rx: contraception prevent endometrial maturation, decrease uterine and tubal motility HRT DUB–stop bleed due to constant estrogen without progesterone Endometriosis–prevent proliferation of ectopic endometrial tissue

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12
Q

Testosterone

A

Testosterone make you a man! rx: hypogonad -: acne and being michael phelps

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13
Q

Flutamide

A

Anti-androgen competitive antagonist for androgen receptor rx: prorstate cancer

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14
Q

Finasteride

A

5a reductase inhibtor block conversion of T–>DHT rx: BPH and balding

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15
Q

Leuprolide

A

Fake GnRH intermittently: stimulate FSh and LH contiuously (on loop) inhibit FSH and LH RX: infertility and prostate cancer

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16
Q

Octreotide

A

Fake somatostatin decrease GI blood flow rx: esophageal variceal bleed

17
Q

Oxytocin

A

Induce uterine contractions induction of labor

18
Q

Vasopression

A

ADH doppleganger increase water abs RX: DI and vasodilatory shock

19
Q

Desmopressin

A

long acting ADH doppleganger RX: DI

20
Q

Levothyroxine

A

Fake thyroid hormone upregulate metabolism and energy expenditure rx: hypothyroid

21
Q

Methimazole

A

inhibit theyroid peroixidse decrease the production of T3/T4 RX: Hyperthyroidism - agranulocyotis aplastic anemia allergy

22
Q

Proypylthiouracil

A

PTU Peripheral thyroid utilizer stoper Stop perpipheral conversion of thyroid hormone Hyperthyroid

23
Q

Insulin

A

insulin ctronol glucose in diabettes - hypoglycemia

24
Q

Glyburide

A

Sulfonylurea enhace insulin release from B islet cells DM II

25
Q

Nateglinide

A

inhance insulin release from B islet cell facilitate early meal mediated insulin secretion DMII

26
Q

Exenatide

A

GLP doppleganger promote insulin synthesis and secretion DMII

27
Q

Metformin

A

Decrease hepatic GNG DMII

28
Q

Rosiglitazone

A

insulin sensitizer via PArry DMII - hepatotoxic

29
Q

Acarbose

A

a glucosidase inhibitor delay intestinal abse of carbs DMII

30
Q

Atoravastatin

A

block endogenous cholesterol synthesis reduce hypercholestertemia

31
Q

Gemfibrozil

A

increase liprotein lipase activity Decrease TG, increase HDL, decrease LDL HyperTG

32
Q

Niacin

A

decrease hepatic synthesis of TG RX: hyper TG - flush

33
Q

Cholestryamine

A

disrupt bile acid recycling decease cholesterol, LDL and increase HDL and TG

34
Q

Ezetimibe

A

inhibit intestinal cholesterol absoprtion rx: hypercholesterolemia

35
Q

Alendronate

A

rx osteoporosis

36
Q

Teriparatide

A

fake PTH treat osteopoosis

37
Q

Cinacalcet

A

mimic bone CA treat hyper PTH