Endometrial Cancer Flashcards Preview

Clinical medicine > Endometrial Cancer > Flashcards

Flashcards in Endometrial Cancer Deck (17):
1

What is the most common gynecologic malignancy?

Endometrial cancer

2

What is the fourth most common cancer in women in the US?

Uterine cancer

3

what is the most common histologic type of uterine cancer?

Adenocarcinoma of the endometrium

4

What are the two histologic categories of endometrial carcinomas?

type 1 tumors include tumors of endometrioid histology that are grade 1, 2; these comprise approx. 80% of endometrial Ca, good prognosis; type 2 account for 10-20% of endometrial carcinomas, they include grade 3, poor prognosis

5

What is the scheme of hyperplasia to cancer?

simple hyperplasia, complex hyperplasia w/out atypia, complex hyperplasia w/ atypia, endometrial CA

6

What percentage of endometrial CA are found to w/ atypical hyperplasia background?

30-40%

7

Presentation of CA?

abnormal uterine bleeding, commonly in postmenopausal women and w/ increasing age in premenopausal women

8

What can protect women from endometrial CA?

oral contraceptives (probably due to progesterone), exss, smoking

9

How is it detected?

abnormal bleeding patterns, cytologic findings on PAP smear, Imaging

10

Cervical cytology findings that need further evaluation with endocervical and endmetrial biopsy?

adenocarcinoma, atypical glandular cells

11

What is the work up?

PE: size, mobility, shape of uterus on bimanual exam, CBC, CMP, US, endometrial sampling

12

A biopsy should be done if...

endometrial thickness >4mm or if there's continued bleeding and

13

how is staging done?

FIGO, if mets, regional lymph nodes, involves adnexa, vagina, or serosa, if invades bladder or bowel- stage 4,

14

What's the treatment?

total extrafasical hysterectomy w/ bilateral salpingo-oophorectomy w/ pelvic and para-aortic lymph node dissection, cytoreduction preformed if mets are evident, adjunctive RT, chemo

15

What does a total hysterectomy include?

the uterus and cervix

16

What does a partial hysterectomy include?

only the uterus

17

Who should get screened?

women w/ lynch syndrome