Energy deficiency syndromes Flashcards
(7 cards)
What is the main energy drain in cattle?
milking
Definition of Ketosis
syndrome of negative energy balance
Who does the ketosis hit most?
high producing, well-conditioned, higher with more lactation numbers
What is the major glucose precursor in cattle? What are others?
proprionate –> OAA –> glucose. lactate, AA and glycerol
What happens to make ketones?
hypoglycemia –> FFA mobilized –> transport to liver –> then 3 things can happen:
- complete oxidation to Acetyl-Coa and NADH which goes into krebs
- incomplete oxidation happens when there is not enough Priopionate (and OAA) to drive the TCA. some goes to TCA and some to acetoacetyl-COa and then BHBA
- re-esterification to FA
Etiologies and syndromes
Primary - the direct loss of glucose because of demands like calving that cause hypoglycemia and then ketogenesos
Secondary - when there is too much ketones (BHBA or acetone) in silage or nutritional deficiency
What are some nutritional disorders that can cause secondary ketosis
cobalt or phosphorus