Enterics/Anaerobes I Flashcards

(87 cards)

1
Q

Antiphagocytic capsule

A

B. fragilis

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1
Q

GI anaerobic abscesses

A

B. fragilis

Clostridium

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2
Q

Only G+ spore formers

A

Clostridium

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2
Q

Vaccine = formalin inactivated toxin

A

Clostridium tetani

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3
Q

A1 fragment ADP-ribosylates GTP binding protein (which incr CFTR, causing osmotic diarrhea)

A

V cholera

V Parahaemolyticus

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3
Q

Black tar heroine users

A

Clostridium botulinum

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4
Q

Rho-family GTPase rearranges actin + stress fibers

A

Clostridium diff

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5
Q

Associated w/ poor sanitation

A

V cholera

V Parahaemolyticus

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5
Q

Only anaerobic endospore formers

A

Clostridium

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6
Q

Disease due to exotoxins and hydrolytic enzymes

A

Clostridium

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7
Q

Abrupt + severe diarrhea + dehydration

A

V cholera

V Parahaemolyticus

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8
Q

Acute mesenteric lynphadenitis

A

Yersinia enterocolitica

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9
Q

Fe-sequestering

A

V vulnificus

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9
Q

Descending flaccid paralysis

A

Clostridium botulinum

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10
Q

Swarming on motility test

A

Proteus

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10
Q

Curved, G-, oxidase +

A

V cholera V Parahaemolyticus

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11
Q

Aggressive abx: clinda, erythromycin, metronidazole

A

B. fragilis

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12
Q

Toxin B = kills colon cells

A

Clostridium diff

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13
Q

“boxcar” bacili

A

Clostridium perfringens

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14
Q

severe watery diarrhea

A

V. cholera

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14
Q

KIA Slant = yellow w/ gas

A

lactose fermented (E. coli, Klebsiella, Enterobacter)

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14
Q

G+ tennis rackets/lollipops

A

Clostridium tetani

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14
Q

Exotoxin mediated = abx don’t work

A

Clostridium tetani

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16
Q

lockjaw + risus sardonicus 1-2wks post exposure

A

Clostridium tetani

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18
Dysentery
Shigella
19
Non-invasive toxin
V cholera V Parahaemolyticus
20
Tryptophan --\> Indole
Shigella (negative = Salmonella)
20
Wound inf in fishermen
V vulnificus
21
KIA Slant = Black w/ gas
glu fermented, H2S formed (Salmonella, Proteus)
21
Motile w/ polar flagella
V cholera V Parahaemolyticus
22
Raw meat/milk with human-human transmission
Campylobacter jejuni Campylobacter fetus
22
Non-inflmm watery diarrhea for 8-12h (no fever, no vomiting)
Clostridium perfringens
23
"Sea gull" appearance
Campylobacter jejuni Campylobacter fetus
24
Incr risk if vit K deficiency (liver disease)
V vulnificus
25
Black colonies
P melaninogenic
26
Rice water stool
V cholera
28
Negative motility test
Shigella, Klebsiella
28
Dx via TCBS + MacConkey Agar
V cholera V Parahaemolyticus
30
AB exotoxin, phage encoded
V cholera V Parahaemolyticus
31
Infant diarrhea
E. coli
31
Slender, curved G- rod
H. pylori
33
Small dose = massive death
Campylobacter jejuni Campylobacter fetus
34
Non-invasive bacteria = not eliminated by host
H pylori
36
Purple on EMB
weak lactose fermenters (Klebsiella)
36
Toxin A = diarrhea
Clostridium diff
38
Grows in higher pH
V cholera V Parahaemolyticus
38
Vomiting, diarrhea, abd cramps
V vulnificus
39
KIA Slant = completely red
no carb fermentation (Pseudomonas)
41
Pseudomembraneous colitis
Clostridium diff
42
Trx = metronidazole
Clostridium diff
43
AB neurotoxin = tetanospasmin
Clostridium tetani
45
Cleavage of V-snares and T-snares
Clostridium botulinum
46
Toxin-coregulated pilus needed for GI colonization
V cholera V Parahaemolyticus
47
Cultured microaerobically
Campylobacter
48
grow at 42'C
Campylobacter jejuni Campylobacter fetus
49
CN damage (vision, dysphagia) --\> resp failure
Clostridium botulinum
51
G-, oxidase +, spirals
Campylobacter jejuni Campylobacter fetus
52
VacA + CagA on PAI
H pylori
53
Fluoroquinolone resistance
Campylobacter jejuni Campylobacter fetus
55
raw canned foods, honey
Clostridium botulinum
57
Causes Guillan-Barre Syndrome (oligo saccharide abs w/ myelin protein)
Campylobacter jejuni Campylobacter fetus
58
clips V-snare via Zn metalloprotease
Clostridium tetani
58
7 antigenic types (A-G)
Clostridium botulinum
59
Diarrhea form seafood
V. parahaemolyticus
61
Fever, then bloody diarrhea w/ pus
Campylobacter jejuni Campylobacter fetus
63
Related to clinda, imipenem, ceftaxidine, moxifloxacin
Clostridium diff
64
Pink/red on MacConkey Agar
E. coli (lac+)
64
Hyperbaric oxygen, PCN, protein-inh for enzymes
Clostridium perfringens
66
alpha-PLC, collagenases, proteases
Clostridium perfringens
67
Infects lining of small intestine, causes systemic spread
Campylobacter jejuni Campylobacter fetus
69
Green + metallic sheen on EMB
lactose fermenters (E. coli)
70
Clear/white on MacConkey Agar
Shigella/Salmonella (lac-)
72
Semi-selective + differential media
EMB MacConkey Agar
73
US Gulf Coast
V vulnificus
74
Blistering, hemorrhagic bullae
V vulnificus
75
KIA Slant = red w/ yellow butt
glu fermented only (Shigella)
76
Floppy Baby Syndrome
Clostridium botulinum (toxin B)
77
Clear on EMB
nonlactose fermenters (Salmonella)
78
Food poisoning (diarrhea, cramps, vomiting)
Salmonella typhimurium
80
Aquatic ecosystems
V cholera V Parahaemolyticus
81
Sorbitol negative
EHEC
82
Gas gangrene + myonecrosis
Clostridium perfringens
83
Fever + Watery --\> bloody diarrhea
Clostridium diff
84
Common in DM
Clostridium perfringens
85
Serotypes include O1 (LPS) and O139
V cholera V Parahaemolyticus
86
toxin blocks release of GABA and glycine
Clostridium tetani
87
MC in warm months
V cholera V Parahaemolyticus