Entrance test Flashcards by Kata Dinga

Q

Benzylpenicillin Na, K

A

Beta lactam AB –> Penicillins –> Narrow spectrum penicillins
Mode of action: Time dependent bactericidal
Mechanism of action: Inhibition of cell wall synthesis

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Q

Benzylpenicillin procaine

A

Beta lactam AB –> Penicillins –> Narrow spectrum penicillins
Mode of action: Time dependent bactericidal
Mechanism of action: Inhibition of cell wall synthesis

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Q

Benzylpenicillin benzathine

A

Beta lactam AB –> Penicillins –> Narrow spectrum penicillins
Mode of action: Time dependent bactericidal
Mechanism of action: Inhibition of cell wall synthesis

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Q

Phenoxymethyl penicillin

A

Beta lactam AB –> Penicillins –> Narrow spectrum penicillins
Mode of action: Time dependent bactericidal
Mechanism of action: Inhibition of cell wall synthesis

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Q

Oxacillin

A

Beta lactam AB –> Penicillins–> Penicillinase stable penicillins
Mode of action –> time dependent bactericidal
Mechanism of action –> inhibition of cell wall synthesis

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Q

Cloxacillin

A

Beta lactam AB –> Penicillins –> Penicillinase stable penicillin
Mode of action: Time dependent bactericidal
Mechanism of action: Inhibition of cell wall synthesis

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Q

Dicloxacillin

A

Beta lactam AB –> Penicillins –> Penicillinase stable penicillins
Mode of action: Time dependent bactericidal
Mechanism of action: Inhibition of cell wall synthesis

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Q

Flucloxacillin

A

Beta lactam AB –> Penicillins –> Penicillinase stable penicillins
Mode of action: Time dependent bactericidal
Mechanism of action: Inhibition of cell wall synthesis

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Q

Amoxicillin

A

Beta lactam AB –> Penicillins –> Broad spectrum penicillins
Mode of action: Time dependent bactericidal
Mechanism of action: Inhibition of cell wall synthesis

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Q

Ampicillin

A

Beta lactam AB –> Penicillins –> Broad spectrum penicillins
Mode of action: Time dependent bactericidal
Mechanism of action: Inhibition of cell wall synthesis

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Q

Ticarcillin

A

Beta lactam AB –> Penicillins –> Penicillins acting against Pseudomonas species
Mode of action: Time dependent bactericidal
Mechanism of action: Inhibition of cell wall synthesis

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Q

Piperacillin

A

Beta lactam AB –> Penicillins –> Penicillins acting against Pseudomonas species
Mode of action: Time dependent bactericidal
Mechanism of action: Inhibition of cell wall synthesis

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Q

Clavulanic acid

A

Beta lactam AB –> Beta lactamase inhibitors
Mode of action: Time dependent bactericidal
Mechanism of action: Inhibition of cell wall synthesis

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Q

Sulbactam

A

Beta lactam AB –> Beta lactamase inhibitors
Mode of action: Time dependent bactericidal
Mechanism of action: Inhibition of cell wall synthesis

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Q

Tazobactam

A

Beta lactam AB –> Beta lactamase inhibitors
Mode of action: Time dependent bactericidal
Mechanism of action: Inhibition of cell wall synthesis

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Q

Cephazoline

A

Beta lactam AB –> 1st generation Cephalosporins
Mode of action: Time dependent bactericidal
Mechanism of action: Inhibition of cell wall synthesis

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Q

Cephapirin

A

Beta lactam AB –> 1st generation Cephalosporins
Mode of action: Time dependent bactericidal
Mechanism of action: Inhibition of cell wall synthesis

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Q

Cefadroxil

A

Beta lactam AB –> 1st generation Cephalosporins
Mode of action: Time dendent bactercidal
Mechanism of action: Inhibition of cell wall synthesis

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Q

Cephalexin

A

Beta lactam AB –> 1st generation Cephalosporins
Mode of action: Time dependent bactericidal
Mechanism of action: Inhibition of cell wall synthesis

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Q

Cefuroxime

A

Beta lactam AB –> 2nd generation Cephalosporins
Mode of action: Time dependent bactericidal
Mechanism of action: Inhibition of cell wall synthesis

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Q

Ceftiofur

A

Beta lactam AB –> 3rd generation Cephalosporins
Mode of action: Time dependent bactericidal
Mechanism of action: Inhibition of cell wall synthesis

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Q

Cefovecin

A

Beta lactam AB –> 3rd generation Cephalosporins
Mode of action: Time dependent bactericidal
Mechanism of action: Inhibition of cell wall synthesis

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Q

Ceftriaxone

A

Beta lactam AB –> 3rd generation Cephalosporins
Mode of action: Time dependent bactericidal
Mechanism of action: Inhibition of cell wall synthesis

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Q

Cefotaxime

A

Beta lactam AB –> 3rd generation Cephalosporins
Mode of action: Time dependent bactericidal
Mechanism of action: Inhibition of cell wall synthesis

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Ceftazidime

Beta lactam AB --> 3rd generation Cephalosporins Mode of action: Time dependent bactericidal Mechanism of action: Inhibition of cell wall synthesis

Cefoperazone

Beta lactam AB --> 3rd generation Cephalosporins Mode of action: Time dependent bactericidal Mechanism of action: Inhibition of cell wall synthesis

Cefquinome

Beta lactam AB --> 4th generation Cephalosporins Mode of action: Time dependent bactericidal Mechanism of action: Inhibition of cell wall synthesis

Imipenem

Beta lactam AB --> Carbapenems Mode of action: Time dependent bactericidal Mechanism of action: Inhibition of cell wall synthesis

Meropenem

Beta lactam AB --> Carbapenems Mode of action: Time dependent bactericidal Mechanism of action: Inhibition of cell wall synthesis

Aztreonam

Beta lactam AB --> Monobactams Mode of action: Time dependent bactericidal Mechanism of action: Inhibition of cell wall synthesis

Tigemonam

Beta lactam AB --> Monobactams Mode of action: Time dependent bactericidal Mechanism of action: Inhibition of cell wall synthesis

Streptomycin

Aminoglycosides Mode of action: Concentration dependent bactericidal Mechanism of action: inhibition of protein synthesis (30S subunit), mistranslation

Neomycin

Aminoglycosides Mode of action: Concentration dependent bactericidal Mechanism of action: inhibition of protein synthesis (30S subunit), mistranslation

Paromycin

Aminoglycosides Mode of action: Concentration dependent bactericidal Mechanism of action: inhibition of protein synthesis (30S subunit), mistranslation

Kanamycin

Aminoglycosides Mode of action: Concentration dependent bactericidal Mechanism of action: inhibition of protein synthesis (30S subunit), mistranslation

Gentamicin

Aminoglycosides Mode of action: Concentration dependent bactericidal Mechanism of action: inhibition of protein synthesis (30S subunit), mistranslation

Tobramycin

Aminoglycosides Mode of action: Concentration dependent bactericidal Mechanism of action: inhibition of protein synthesis (30S subunit), mistranslation

Amikacin

Aminoglycosides Mode of action: Concentration dependent bactericidal Mechanism of action: inhibition of protein synthesis (30S subunit), mistranslation

Apramycin

Aminoglycosides Mode of action: Concentration dependent bactericidal Mechanism of action: inhibition of protein synthesis (30S subunit), mistranslation

Spectinomycin

Aminoglycosides Mode of action: BACTERIOSTATIC (only AG) Mechanism of action: inhibition of protein synthesis (30S subunit), mistranslation

Chlortetracycline

Tetracycline --> short acting Mode of action: bacteriostatic Mechanism of action: inhibition of protein synthesis (30S)

Oxytetracycline

Tetracycline --> short acting Mode of action: bacteriostatic Mechanism of action: inhibition of protein synthesis (30S)

Tetracycline

Tetracycline --> short acting Mode of action: bacteriostatic Mechanism of action: inhibition of protein synthesis (30S)

Doxycycline

Tetracycline --> long acting Mode of action: bacteriostatic Mechanism of action: inhibition of protein synthesis (30S)

Minocycline

Tetracycline --> long acting Mode of action: bacteriostatic Mechanism of action: inhibition of protein synthesis (30S)

Erythromycin

Macrolides Mode of action: bacteriostatic Mechanism of action: inhibition of protein synthesis (50S)

Azithromycin

Macrolides Mode of action: bacteriostatic Mechanism of action: inhibition of protein synthesis (50S)

Clarithromycin

Macrolides Mode of action: bacteriostatic Mechanism of action: inhibition of protein synthesis (50S)

Spiramycin

Macrolides Mode of action: bacteriostatic Mechanism of action: inhibition of protein synthesis (50S)

Tylosin

Macrolides Mode of action: bacteriostatic Mechanism of action: inhibition of protein synthesis (50S)

Tylvalosin

Macrolides Mode of action: bacteriostatic Mechanism of action: inhibition of protein synthesis (50S)

Tilmicosin

Macrolides Mode of action: bacteriostatic Mechanism of action: inhibition of protein synthesis (50S)

Tulathromycin

Macrolides Mode of action: bacteriostatic Mechanism of action: inhibition of protein synthesis (50S)

Gamithromycin

Macrolides Mode of action: bacteriostatic Mechanism of action: inhibition of protein synthesis (50S)

Tildipirosin

Macrolides Mode of action: bacteriostatic Mechanism of action: inhibition of protein synthesis (50S)

Lincomycin

Lincosamides Mode of action: bacteriostatic Mechanism of action: inhibition of protein synthesis (50S)

Clindamycin

Lincosamides Mode of action: bacteriostatic Mechanism of action: inhibition of protein synthesis (50S)

Tiamulin

Pleuromutilins Mode of action: bacteriostatic Mechanism of action: inhibition of protein synthesis (50S)

Valnemulin

Pleuromutilins Mode of action: bacteriostatic Mechanism of action: inhibition of protein synthesis (50S)

Chloramphenicol

Phenicols Mode of action: bacteriostatic Mechanism of action: inhibition of protein synthesis (50S)

Florefenicol

Phenicols Mode of action: bacteriostatic Mechanism of action: inhibition of protein synthesis (50S)

Thiamphenicol

Phenicols Mode of action: bacteriostatic Mechanism of action: inhibition of protein synthesis (50S)

Bacitracin

Peptide AB --> Polypeptide AB Mode of action: Concentration dependent bactericidal Mechanism of action: They act like cationic detergent

Polymyxin B

Peptide AB --> Polypeptide AB Mode of action: Concentration dependent bactericidal Mechanism of action: They act like cationic detergent

Polymyxin E = Colistin

Peptide AB --> Polypeptide AB Mode of action: Concentration dependent bactericidal Mechanism of action: They act like cationic detergent

Vancomycin

Peptide AB --> Glycopeptide AB Mode of action: Time dependent bactericidal Mechanism of action: Inhibition of cell wall synthesis

Teicoplanin

Peptide AB --> Glycopeptide AB Mode of action: Time dependent bactericidal Mechanism of action: Inhibition of cell wall synthesis

Rifampicin

Rifamycines Mode of action: Time dependent bactericidal Mechanism of action: inhibit bacterial DNA dependent RNA polymerase

Mupirocin

Pseudomonic acid Mode of action: bactericidal Mechanism of action: inhibition of cell wall synthesis

Fosfomycin

Phosphonic acid derivate Mode of action: bactericidal Mechanism of action: inhibition of cell wall synthesis

Fusidic acid

Fusidic acid Mode of action: bacteriostatic Mechanism of action: inhibition of protein synthesis

Sulfadimidine

Sulphonamides Mode of action: separately bacteriostatic and combination: time dependent bactericidal Mechanism of action: inhibition of folic acid synthesis

Sulfadiazine

Sulphonamides Mode of action: separately bacteriostatic and combination: time dependent bactericidal Mechanism of action: inhibition of folic acid synthesis

Sulfachlorpyridazine

Sulphonamides Mode of action: separately bacteriostatic and combination: time dependent bactericidal Mechanism of action: inhibition of folic acid synthesis

Sulfachlorpyrazine

Sulphonamides Mode of action: separately bacteriostatic and combination: time dependent bactericidal Mechanism of action: inhibition of folic acid synthesis

Sulfamethoxazole

Sulphonamides Mode of action: separately bacteriostatic and combination: time dependent bactericidal Mechanism of action: inhibition of folic acid synthesis

Sulfadoxine

Sulphonamides Mode of action: separately bacteriostatic and combination: time dependent bactericidal Mechanism of action: inhibition of folic acid synthesis

Sulfaquinoxaline

Sulphonamides Mode of action: separately bacteriostatic and combination: time dependent bactericidal Mechanism of action: inhibition of folic acid synthesis

Sulfasalazine

Sulphonamides Mode of action: separately bacteriostatic and combination: time dependent bactericidal Mechanism of action: inhibition of folic acid synthesis

Trimethoprim

Diaminopyrimidines Mode of action: separately bacteriostatic and combination: time dependent bactericidal Mechanism of action: inhibition of folic acid synthesis

Baquiloprim

Diaminopyrimidines Mode of action: separately bacteriostatic and combination: time dependent bactericidal Mechanism of action: inhibition of folic acid synthesis

Nalidixic acid

Fluoroquinolones --> 1st generation Mode of action: concentration dependent bactericidal Mechanism of action: inhibition of DNA synthesis

Flumequine

Fluoroquinolones --> 2nd generation Mode of action: concentration dependent bactericidal Mechanism of action: inhibition of DNA synthesis

Norfloxacin

Fluoroquinolones --> 2nd generation Mode of action: concentration dependent bactericidal Mechanism of action: inhibition of DNA synthesis

Ciprofloxacin

Fluoroquinolones --> 2nd generation Mode of action: concentration dependent bactericidal Mechanism of action: inhibition of DNA synthesis

Enrofloxacin

Fluoroquinolones --> 2nd generation Mode of action: concentration dependent bactericidal Mechanism of action: inhibition of DNA synthesis

Danofloxacin

Fluoroquinolones --> 2nd generation Mode of action: concentration dependent bactericidal Mechanism of action: inhibition of DNA synthesis

Difloxacin

Fluoroquinolones --> 2nd generation Mode of action: concentration dependent bactericidal Mechanism of action: inhibition of DNA synthesis

Marbofloxacin

Fluoroquinolones --> 2nd generation Mode of action: concentration dependent bactericidal Mechanism of action: inhibition of DNA synthesis

Levofloxacin

Fluoroquinolones --> 3rd generation Mode of action: concentration dependent bactericidal Mechanism of action: inhibition of DNA synthesis

Sparfloxacin

Fluoroquinolones --> 3rd generation Mode of action: concentration dependent bactericidal Mechanism of action: inhibition of DNA synthesis

Pradofloxacin

Fluoroquinolones --> 4th generation Mode of action: concentration dependent bactericidal Mechanism of action: inhibition of DNA synthesis

Moxifloxacin

Fluoroquinolones --> 4th generation Mode of action: concentration dependent bactericidal Mechanism of action: inhibition of DNA synthesis

Nitrofurantoin

Nitrofurans Mode of action: bactericidal Mechanism of action: destroy the DNA of bacteria

Furazolidone

Nitrofurans Mode of action: bactericidal Mechanism of action: destroy the DNA of bacteria

Metronidazole

Nitroimidazoles Mode of action: concentration dependent bactericidal Mechanism of action: destroy the DNA of bacteria

Ronidazole

Nitroimidazoles Mode of action: concentration dependent bactericidal Mechanism of action: destroy the DNA of bacteria

Tinidazole

Nitroimidazoles Mode of action: concentration dependent bactericidal Mechanism of action: destroy the DNA of bacteria

Bacteriostatic agents

1. Tetracyclines 2. Macrolides 3. Phenicols 4. Pleuromutilins 5. Lincosamides 6. Fusidic acid 7. Sulfonamides (in combi: time dependent bactericidal) 8. Diaminopyrimidines (in combi: time dependent bactericidal) 9. Spectinomycin --> only Aminoglycoside (rest: conc.dep.cidal)

Time dependent bactericidal

1. Penicillins (narrow, broad spectrum, penicillinase stable, penic. acting against pseudomonas) 2. Beta lactamase inhibitors 3. Cephalosporins 4. Carbapenems 5. Monobactams 6. Polypetide AB--> only Glycopeptide ABs 7. Rifamycines 8. IF COMBI: Sulphonamides 9. IF COMBI: Diaminopyrimidines