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Pathology > Environmental Pathology > Flashcards

Environmental Pathology Flashcards

1
Q

Phase II Reactions

A

Glucoronidation; Sulfation; Methylation; Conjugation

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2
Q

Phase I Reactions

A

Hydrolysis; Oxidation; Reduction

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3
Q

Most important preventable COD and disease in the USA.

A

Smoking

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4
Q

Metabolite of nicotine; used for screening.

A

Cotinine

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5
Q

Leading cause of premature death in the USA.

A

Tobacco

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6
Q

Primary carcinogens in tobacco.

A

Polycyclic HC

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7
Q

Rate limiting enzyme in ROH metabolism.

A

ROH dehydrogenase

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8
Q

MC cause of thiamine deficiency.

A

Alcohol Abuse

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9
Q

Key substrate for TG synthesis in the liver.

A

Glycerol 3 Phosphate

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10
Q

MC Systemic complication of IVDU.

A

Hepa B

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11
Q

MC cause of HPN in young women.

A

OC

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12
Q

MC COD due to a venomous bite.

A

Bee, wasp or hornet sting.

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13
Q

HPN from OC is brought upon by synthesis of what hormone?

A

Angiotensinogen

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14
Q

MC cause of accidental death in people ages 1 - 39 y/o.

A

MVC

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15
Q

Transverse bands in nails in As poisoning.

A

Mees lines

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16
Q

First sign of CO poisoning.

A

HA

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17
Q

Characteristic of CO poisoning (skin color).

A

Cherry red

18
Q

Tx of CN poisoning.

A

Amyl nitrate and thiosulfate

19
Q

End metabolic product of ethylene glycol.

A

Oxalic acid

20
Q

End metabolic product of isopropyl alcohol.

A

Acetone

21
Q

Most important source of Hg poisoning.

A

Fish

22
Q

More than 50% of deaths in child abuse are due to this syndrome.

A

Shaken Baby Syn

23
Q

MC COD in burn ptx.

A

Sepsis due to P. aeruginosa

24
Q

Difference between heat exhaustion and heat stroke.

A

HS - anhidrosis

25
Q

Most common drowning.

A

Wet drowning

26
Q

Most and least sensitive tissue to radiation.

A

Most - lymphoid tissue

Least - bone

27
Q

First change in hematopoietic tissues brought about by radiation.

A

Lymphopenia

28
Q

Most frequent type of cancer caused by radiation.

A

Acute leukemia

29
Q

Most damaging nonionizing radiation.

A

UVB

30
Q

Most common UVB light related skin cancer.

A

Basal cell carcinoma

31
Q

Most important factor in determining daily energy expenditure.

A

BMR

32
Q

Most important factor in determining BMR.

A

Body weight

33
Q

Characteristic of kwashiorkor.

A

Pitting edema

34
Q

MC COD in anorexia nervosa.

A

Ventricular arrhythmia

35
Q

Hormone maintaining energy balance.

A

Leptin

36
Q

First sign of Vit A deficiency.

A

Night Blindness

37
Q

Major source of Vit D

A

Sunlight

38
Q

MC cause of Vit D deficiency

A

Renal failure

39
Q

MC source of Vit K

A

Endogenous bacteria

40
Q

MC cause of B12 deficiency.

A

Pernicious anemia

41
Q

MC cause of folate deficiency.

A

ROH Excess

Pathology (5 decks)

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