Enzimas

Question 1

Aminotransferasas (transaminasas)

Answer 1

Aminoácido —>cetoácido

Question 2

Glutamato deshidrogenasa

Answer 2

Glutamato —> NH3, cetoácido

Question 3

Carbamoil fosfato sintasa I

Answer 3

NH3 (CO2 + 2ATP) —> Carbamoil fosfato

Question 4

Glutamina sintasa

Answer 4

Glutamato + NH3 + ATP —> glutamina

Question 5

Glutaminasa

Answer 5

Glutamina —> Glutamato + NH3 + ATP

Question 6

Ornitina transcarbamoilasa

Answer 6

Carbamoil fosfato + ornitina —> citrulina

Question 7

Argininosuccinato sintetasa

Answer 7

Citrulina + aspartato + 2ATP —> argininosuccinasa

Question 8

Argininosuccinasa

Answer 8

Argininosuccinato —> arginina + fumarato

Question 9

Arginasa

Answer 9

Arginina —> urea + ornitina

Question 10

PRPP sintetasa (fosforribosil pirofosfato)

Answer 10

Ribosa - 5 - fosfato —> 5 - fosforribosil pirofosfato

Question 11

Paso 2 de la síntesis de purinas (enzima):

Answer 11

Amidofosforribosiltransferasa

Question 12

Adenilosuccinato sintetasa

Answer 12

IMP + aspartato - GTP —> adenilsuccinato

Question 13

Adenilosuccinato liasa

Answer 13

Adelsuccinato —> AMP

Question 14

Adenilato cinasa

Answer 14

AMP + Pi —> ADP

Question 15

Nucleótido difosfocinasa

Answer 15

ADP + Pi —> ATP

GDP + Pi —> GTP

Question 16

IMP deshidrogenasa

Answer 16

IMP + H2O + NAD —> XMP (xantosina monofosfato)

Question 17

GMP sintetasa

Answer 17

XMP + ATP —-> GMP

Question 18

Guanilato cinasa

Answer 18

GMP + Pi —> GDP

Question 19

Adenina fosforribosil transferasa

Answer 19

Adenina —> AMP

Question 20

Hipoxantina - guanina - fosforribosil transferasa

Answer 20

Hipoxantina —> IMP

Guanina —> GMP

Question 21

5´nucleotidasa

Answer 21

AMP, IMP, GMP (nucleótido) —> (nucleósido)

Question 22

Nucleósido de purina fosforilasa

Answer 22

(Nucleósido) —> purina libre

Question 23

AMP desaminasa

Answer 23

AMP —> IMP

Question 24

Adenosina desaminasa

Answer 24

Adenina —> inosina

Question 25

Xantina oxidasa

Answer 25

Hipoxantina —> xantina —> ácido úrico

Question 26

Guanina desaminasa

Answer 26

Guanosina —> xantina

Question 27

Carbamoil fosfato sintetasa II

Answer 27

HCO3 + glutamina —> Carbamoil fosfato

Question 28

Aspartato transcarbamoilasa

Answer 28

Carbamoil fosfato —> Carbamoil aspartato

Question 29

Dihidroorotasa

Answer 29

Carbamoil aspartato —> dihidroorato o ácido dihidroorótico

Question 30

Dihidrooratato deshidrogenasa

Answer 30

dihidroorato o ácido dihidroorótico —> orotato o ácido orótico

Question 31

Orotato fosforribosil transferasa

Answer 31

orotato o ácido orótico —> OMP (ornitidina monofosfato)

Question 32

Orotidilato descarboxilasa

Answer 32

OMP —> UMP Nota: La UMP es el precursor de nucleótidos de pirimidinas

Question 33

UMP cinasa y nucleótido difosfocinasa

Answer 33

UMP —> UDP —> UTP

Question 34

CTP sintetasa

Answer 34

UTP —> CTP

Question 35

Uracilo fosforribosil transferasa (URRTasa)

Answer 35

Uracilo —> UMP

Question 36

Uridina-citidina cinasa

Answer 36

Uridina —> UMP Citadino —> CMP

Question 37

Tímidina cinasa

Answer 37

Timidina —> TMP

Question 38

Nucleótido cinasa y difosfocinasa

Answer 38

UMP —> UDP —> UTP (aplica para CMP y TMP)

Question 39

5´nucleotidasa y nucleósido hidrolasa

Answer 39

CMP —> (nucleósido) —> (base libre) = uracilo, citosina, timina

Question 40

Citosina desaminasa

Answer 40

Citosina —> uracilo

Question 41

Dihidropirimidina deshidrogenasa

Answer 41

Uracilo —> dihidrouracilo Timina —> dihidrotimina

Question 42

Dihidropirimidinasa

Answer 42

5,6-dihidrouracilo → N-carbamoil-β-alanina 5,6-dihidro-timina → N-carbamoil-β-aminoisobutirato

Question 43

B - ureido propionasa

Answer 43

N-carbamoil-β-alanina —> B-alanina N-carbamoil-β-aminoisobutirato —> B-aminoisbutirato