Enzyme Inducers and Inhibitors Flashcards
1
Q
Which drugs broadly are inducers?
A
Anti-epileptics
Barbiturates
Rifampicin
St John’s Wort
2
Q
What effect do inducers have on INR?
A
Decrease INR
3
Q
Which lifestyle choices cause enzyme induction?
A
Chronic alcohol
Smoking
4
Q
Which drugs broadly are inhibitors?
A
Antibiotics: Cipro, clarithromycin
Isoniazid
Omperazole
SSRIs
Valproate
(Amiodarone, allpurinol, ritonavir)
5
Q
What do inhibitors do to INR?
A
Increase it
6
Q
What lifestyle choices cause enzyme inhibition?
A
Acute alcohol intake
