Enzyme-targeting drugs Flashcards

1
Q

ACYCLOVIR

A

Viral DNA Polymerase

Herpes

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2
Q

AMPRENAVIR

A

HIV Viral protease

AIDS

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3
Q

ALLOPURINOL

A

Xanthine oxidase

Gout

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4
Q

ASPIRIN

A

Cyclooxygenase

Inflammation/pain

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5
Q

CARBIDOPA

A

Aromatic-L-amino-acid decarboxylase

Parkinson’s

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6
Q

CELEBREX

A

Cyclooxygenase

Inflammation/pain

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7
Q

CLAVULANATE

A

Beta-lactamase

Bacterial resistance

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8
Q

DIGOXIN

A

Na/K ATPase

Congestive heart failure

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9
Q

DUTASTERIDE

A

Type I & type II 5 steroid alpha-reductase

Benign prostate hyperplasia

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10
Q

EFAVIRENZ

A

Reverse transcriptase

AIDS

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11
Q

ETOPOSIDE

A

Topoisomerase II

Cancer

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12
Q

LISINOPRIL

A

Angiotensin-Converting Enzyme

Hypertension

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13
Q

METHOTREXATE

A

dihydrofolate reductase

Cancer/immunosuppresion

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14
Q

OMEPRAZOLE

A

H+/K+ ATPase enzyme

Peptic ulcer

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15
Q

TRIMETHOPRIM

A

Bacterial dihydrofolate reductase

Bacterial infection

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16
Q

DICUMAROL

A

vit. K-epoxide-33 reductase

anticoagulant

17
Q

PENICILLIN

A

Transpeptidase

Bacterial infection

18
Q

SULFONAMIDE

A

pteroid synthase

Bacterial infection

19
Q

6-MERCAPTOPURINE

A

adenylosuccinate synthetase

Cancer