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Flashcards in Enzymes Deck (10)
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1
Q

Whats a cofactor?

A

A non protein part needed for functionality

2
Q

Whats a coenzyme?

A

An enzyme made from a vitamin

3
Q

What’s a prosthetic group?

A

A cofactor that is covalently bound to the enzyme.

4
Q

What’s an apoenzyme?

A

The protein component of an enzyme containing the prosthetic group

5
Q

How do enzymes catalyse reactions?

A
  • Lower activation energy
  • Increase rate of spontaneous reactions
  • Accelerate movement towards equilibrium.
6
Q

What does Km tell you?

A

The affinity for the enzyme of the substrate

7
Q

How do competitive inhibitors work and what is their affect on Km and Vmax?

A
  • Tend to resemble the substrate
  • Bind to active site
  • Km increases
  • Vmax remains the same
8
Q

How do non-competitive inhibitors work and what is their affect on Km and Vmax?

A
  • They bind to a non active site on the enzyme.
  • The substrate can still bind to the active site so Km remains the same
  • Vmax decreases.
9
Q

What is the random model when referring to enzyme-substrate binding?

A
  • It doesn’t matter which way the substrates bind the outcome will be the same
10
Q

What is the ordered sequential model?

A

One substrate HAS to bind before the other and the other has to leave first