Enzymes of Cholesterol Synthesis Flashcards

1
Q

Desmolase: Substrate/Product + Alter name + Location

A

Substrate: Chlesterol
Product: Pregnenolone

Alter: CYP11A1
Location: Mitochondrai

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2
Q

3B: Substrate/Product + Location

A

Substrate: Pregnolone
Product: Progesterone
Location: ER

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3
Q

17a: Substrate/Product + Alter name + Location

A

Substrate: Pregnenolone or Progesterone
Product: 17-hydroxypregnenolone or 17-hydroxyprogesterone

Alter: CYP17A1
Location: ER

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4
Q

21: Substrate/Product + Alter name + Location

A

Substrate: Progesterone or 17-hydroxyprogesterone
Products: Deoxycorticosterone or 11-deoxycortisil

Alter: CYP21A2
Location: ER

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5
Q

11: Substrate/Product + Alter name + Location

A

Substrate: Deoxycorticosterone or 11-deoxycortisol
Products: COrticosterone or Cortisol

Alter: CYP11B
Location: Mitochondria

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6
Q

18: Substrate/Product + Alter name + Location

A

Substrate: Corticosterone
Products: Aldosterone

Alter: CYPB2
Location Mitochondria

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7
Q

Aromatase:Substrate/Product + Alter name + Location

A

Substate: Androstenedione or Testosterone
Product: Estradiol

Alter: CYP19
Location ER

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