Epi Cell Bio and the Cell Cycle Flashcards

(32 cards)

1
Q

what si epi

A

tissue of closely packed cells that forms a surface or lines of cavity or tube
line surfaces
protective
secretary

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2
Q

how ar epi cells classed num layers

A

num layers
- one - simple or multi (pseudostratfeid)
2/more - stratified

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3
Q

how are epi cells classed by shape

A

flattened - squamous
cubes - cuboidal
columns - columnar

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4
Q

what si the function of oral mucous epi

A

protect
perm barrier
protect fluid loss

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5
Q

what si a standard strutter of epi cell

A
basla lamina 
hemidesmosome 
desmosome 
keratin filaments
nu c
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6
Q

what binds two epi cells together

A

desmosomes - communications done though this also

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7
Q

where is basal lamina

A

between mesenchyme
and epi
allowing interaction with underlying storm

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8
Q

what is cell rpoliferation

A

an increase in the number of cells asa result of cell growth and cell divison

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9
Q

wha kind of epi is oral mucosa

A

stratified squamous epi

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10
Q

wehre is masticatory oral mucosa

A

gingival and hard palate

keranised

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11
Q

whereis lining oral mucosa

A

floor mouth
buccal regions
oes non keratinised

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12
Q

where is some specialised oral muscos

A

dorsum of tongue

both keratinise and non

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13
Q

how does a cell reproduce

A

by eprfomrig orderly sequence of events which duplicates content then divides into two

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14
Q

what is a simple cell cycle

A

chromosome replication and cell growth

chromo segregation

cell division

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15
Q

how si the cells cel ontorlled

A
timer
order
on off switch 
robustness 
adaptability
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16
Q

what re the phases

17
Q

what are the cell cycle checkpoints

A

G1 - enviro fave?
G2 - dna rep
M - chromos on spindle

18
Q

what are the phases of interphase onwards

A
prophase 
metaphase
anaphase 
telophase
cytokinesis
19
Q

what are some cell cycle ‘controllers’

A

protein kinases
cyclin dept kinases
phosphorylation proteins

20
Q

what are cyclin dept kinases controlled by

21
Q

what happens to cyclins during cell cycle

A

circle of synthesis

22
Q

what are cyclin classes

A

4 classes

  • G1/s at end G1 - dna replication
  • S bind Cdk’s during s = imitate dna rep
  • M - mitosis
23
Q

what si he cyclin complex for cyclin D

24
Q

what si he cyclin complex for cyclin E

25
cyclins dont only activate cdk but
directs it
26
what si a growth factor
polypeptides that control animal cel grown and diff | store and rel into ECM
27
wat is a transcription factor
protein tha regulates the activity of RNA polymerase
28
what is the proliferation control
receptors signalling ECM phosphorylation
29
what does a cell proliferation unit have
progenitor cells basal cell layer | divide to clusters
30
what is cell cycle cyclin over expression always
phsophsyrlaed
31
what is the guardian of genome
P53
32
what are stem cels
not terminally diff divide withoutlimt each daughter cell has a choice