Epi Final Exam Flashcards

(67 cards)

1
Q

Epidemiology is the study of (3 D’s)

A

distribution, determinants, and dynamics of disease in a population

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Name 5 approaches to epidemiology

A
quantitative
medical ecology
herd health
clinical epidemiology
descriptive
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Which historical figure is credited with controlling the Rinderpest outbreak using testing and depopulation

A

Lancisi

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

which historical figure determined that cholera was caused by contaminated water and not “bad air”

A

John snow

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Which historical figure is credited with compiling the bills for mortality into a census (first demographer)

A

John Graunt

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Which historical figure was the first veterinarian to graduate from cornell and also became head ot the bureau of animal industries?

A

Daniel salmon

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Which historical figure worked with Kilbourne to discover that Texas Cattle fever was a tick-borne disease?

A

Theobald smith

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Which historical figure was involved with determining how yellow fever was transmitted?

A

Dr. Walter Reed

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What is syndromic surveillance?

A

determining the presence of a disease before an actual diagnosis is made

(i.e. if the sale of Tamiflu is going up, there must be flu outbreaks occurring)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What are the steps of the epidemiologic cycle?

A
identify problem
collect info
formulate hypothesis
observe
classify information
collect data
process/analyze data
solve problem (OR find a new problem)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

The purposeful use of microorganisms or toxins derived from living organisms to cause death or disease in humans, animals, or plants in civilian setting

A

Bioterrorism

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Describe a category A bioterrorism agent; give 3 examples

A

highest priority;
easily disseminates, high mortality

anthrax, plague, smallpox

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Describe a category B bioterrorism agent; give 3 examples

A

moderately easy dissemination, moderate mortality

brucellosis, glanders, Q fever, viral encephalitis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Describe a category C bioterrorism agent; give 2 examples

A

high mortality; possible future use

Nipah virus and Hanta virus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Name the 4 classifications of zoonotic diseases by transmission cycle

A

meta-zoonoses
direct zoonoses
cyclo-zoonoses
sapro-zoonoses

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

life cycle requires biological transmission by invertebrate host

A

Meta-zoonoses

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

transmission from infected vertebrate to human by contact, vehicle, or mechanical vector

A

Direct zoonoses

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

transmission cycle requires more than one vertebrate host

A

cyclo-zoonoses

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

non-animal site serves as the true reservoir for the agent

A

sapro-zoonoses

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

Concerning temporal disease patterns, define:

1) sporadic
2) epidemic
3) endemic
4) diurnal

A

1) occurs rarely and w/o regularity
2) occurrence of a disease in a population in EXCESS of what is normally expected
3) occurs with predictable regularity (habitual presence)
4) changes that occur over a short period of time

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

Concerning temporal disease patterns, define:

1) cyclic
2) seasonal
3) secular

A

1) periodic changes over several years (due to fluctuations in population immunity)
2) occurs one time of the year, every year
3) gradual change over a long period of time

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

What are the two types of epidemics?

A

Common source (all people infected at once)

Propagated (infectious disease that spreads)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

Ability of an agent to replicate and cause disease in its host

A

pathogenicity

Virulence=severity of the disease

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

Animal use and level of husbandry are what type of host determinants?

A

Extrinsic

intrinsic= sex, breed, age, species, etc

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
What are the 3 most allergy-inducing animals?
rat urine guinea pigs cats (dander & saliva)
26
Which tick species is associated with tick related meat allergies?
Amblyoma americanum (lonestar tick)
27
Most common bacteria isolated from animal bites?
Pasteurella multocida
28
Medical name for cat scratch disease?
Subacute regional lymphadenitis
29
Name 2 risk factors for Caponocytophagia
1) splenectomy | 2) alcohol abuse
30
The term for: 1) rabies virus ascending the nerves to reach spinal cord 2) rabies virus descending to salivary glands
1) centripetal | 2) centrifugal
31
Bite, contact, inhalation, and ingestion of rabies are all what type of transmission?
Horizontal, direct transmission
32
Can rabies be transmitted vertically (in utero)
Yes (skunks...timing matters)
33
Concerning Herpes B Virus (Cercopithecine herpes 1): 1) reservoir host 2) risk to humans
1) Macaque | 2) fatal infections in humans
34
An effective mechanism to decontaminate soil infected with anthrax spores?
5% lye
35
Which group of individuals is at highest risk from erysipeliod
aquatic animal handlers
36
Most important reservoir host for lepto?
Rats | survives longest in rat and swine urine
37
T/F: there is a vaccination available against lepto for BOTH dogs and cows
True!
38
A shipment of giant Gambian rats to the US was associated with outbreak of what disease?
Monkey pox
39
Proper solution to disinfect when monkey pox is suspected
0.5% sodium hypocholorite
40
List the progression of pox virus lesions
papule-->vesicle-->pustule-->crust
41
Which hepatitis virus is zoonotic? Animal most commonly associated with transmission to humans?
Hepatitis A Chimpanzees
42
Primary source of zoonotic cryptosporidiosis?
Pets (cats and dogs)
43
Ocular larval migrans can immitate what disease?
Human retinoblastoma
44
Which is more severe in humans: 1) zoonotic scabies 2) human scabies
Human scabies--burrows deeper | other is self-limiting
45
Systematic errors in a study that lead to a false conclusion
bias
46
Distortion of the effect of an exposure of interest because it is mixed with effect of an extraneous factor
Confounding
47
Name the 4 different types of probability sampling
simple random systematic stratified random cluster
48
Name 3 advantages and disadvantages for prospective cohort studies?
A: 1) establish incidence 2) true relative risk 3) assess more than 1 outcome D: 1) expensive (takes time) 2) small number of determinants 3) time (delayed results)
49
Name 1 advantage and 2 disadvantages for retrospective case control studies
A: 1) inexpensive/quick D: 1) information not available 2) time sequence unknown
50
Which animals are involved in URBAN echinococcosis 1) E. granulosus 2) E. multilocularis
1) dog--sheep | 2) dog/cat--rodents
51
Which animals are involved in SYLVATIC echinococcosis 1) E. granulosus 2) E. multilocularis
1) wolf--moose | 2) fox---rodent
52
Which systemic mycoses are associated with: 1) waterways 2) bird droppings 3) rodent burrows/deserts
1) blastomycoses 2) histomycoses & cryptococcosis 3) coccidioidomycosis
53
Name the term: 1) how reproducible a test is 2) ability of a test to give you a true measure of disease presence
1) reliability | 2) accuracy
54
How does decreasing disease prevalence affect predictive value positive?
decreases it
55
Positive serology + non-specific agglutinins =
false positive
56
# Define: 1) sensitivity | 2) specificity
1) ability to give a positive result when animal is disease | 2) ability to give a negative result when the animal is NOT diseased
57
Name 3 diseases associated with tick species Ixodes scapularis
Lyme disease anaplasmosis babesiosis
58
Primary tick spp. responsible for tick borne relapsing fever
Ornithodoros hermisii
59
Pathognomonic sign for lyme disease in humans?
erythema migrans (target lesion)
60
Most common signs of RMSF in humans?
High fever Rash Nausea Arthralgia (joint pain)
61
Which type of Tularemia is limited to north america and causes more serious disease in humans?
Type A *Reservoir--rabbits & ticks
62
Less fatal than Type A, Type B tulerima is associated with what types of animals?
non-rabbit mammals (usually water/aquatic animals)
63
Name 3 tick spp. associated with tulerima transmission
1) Dermacenter variabilis 2) D. andersoni 3) Ambyloma americanum
64
Sentinel chickens and wild bird mist netting are useful surveillance tools for?
Arthropod borne encephalitides
65
Which parasite causes Chagas disease
Trypanosoma cruzi
66
Briefly describe how chagas disease is transmitted
Reduviid bites for blood meal and also defecates on the skin, when you scratch, you move the feces into the wound (feces contains the parasite)
67
Most important flea vector for plague in US?
Oropsylla montana