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Flashcards in Epibulbar Deck (26)
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1

conj naevus - sign of potential malignancy

palpebral or forniceal, prominent feeder vessels, sudden growth or increase in pigmentation, development after second decade

2

conj papilloma - treatment

excision, cryotherapy, subconj interferon alfa, carbon dioxide laser vaporization, topical mitomycin C, cimetidine

3

Limbal dermoid - where, syndromes

inferotemp. limbus, Goldenhar, Treacher Collins, Linear naevus sebaceus of Jadasohn

4

Goldenhar syndrome

mr, epibulbar dermoid, upper eyelid coloboma, preauricular skin tags, vertebral anomalies, hypoplasia maxilla mandibula

5

linear nevus sebaceous syndrome

lipodermoids (or dermolipomas), Complex choristomas

6

Goldenhar syndrome name

oculoauriculovertebral dysgenesis

7

Treatment for PAM

excision with cryotherapy

8

Lesar-Trelat sign

sudden onset of numerous seborrheic keratoses --> work-up for gastrointestinal adenocarcinoma

9

PAM - uni or bi, in whom

uni, light-colored, middle-age

10

PAM - % progress to conj melanoma

30-50%

11

PAM - location suspicious for atypia

palpebral, fornix, plica, caruncule

12

Benign melanosis - where

perilimbal conj, may extend onto the peripheral cornea ("striate melanokeratosis")

13

Nevus of Ota

oculodermal melanocytosis

14

Risk of melanoma in Risk of melanoma in ocular or oculodermal melanocytosis

1/400

15

Risk of glaucoma in ocular or oculodermal melanocytosis

10%

16

% of conj melanoma arise from PAM

70%

17

Factors with risk of PAM progression

more than 3 hour clocks of pigmentation, caruncule, fornix, palpebral

18

Conj melanoma - recurrence rate

50%

19

Origin of conj melanoma

70% PAM, 25% de novo, 5% nevus

20

Melanoma - poor prognosis

palpebral, fornix, caruncule, eyelid margin. tchickness >1.8mm, pagetoid, full-thickness intraepithelial spread, lymphatic invasion, mixed cell type, de novo, not limbus, residual involvement at the surgical margin

21

Margin in excision of nevus

2mm

22

Reddish brown nodule on the surface on the caruncule

onkocytoma

23

slow-growing cystadenoma

onkocytoma

24

onkocytoma cystadenoma - origin

ductal and acinar cells of main and accessory lacrimal glands

25

Treatment of CIN

excision with 3-4 mm margins and cryotherapy, topical IF2b, MMC, 5-FU

26

Ataxia-Telangiectasia

AR, Louis-Barr syndrome, can't initiate saccades, carriers - risk of breast cancer