Flashcards in Epibulbar Deck (26)
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1
conj naevus - sign of potential malignancy
palpebral or forniceal, prominent feeder vessels, sudden growth or increase in pigmentation, development after second decade
2
conj papilloma - treatment
excision, cryotherapy, subconj interferon alfa, carbon dioxide laser vaporization, topical mitomycin C, cimetidine
3
Limbal dermoid - where, syndromes
inferotemp. limbus, Goldenhar, Treacher Collins, Linear naevus sebaceus of Jadasohn
4
Goldenhar syndrome
mr, epibulbar dermoid, upper eyelid coloboma, preauricular skin tags, vertebral anomalies, hypoplasia maxilla mandibula
5
linear nevus sebaceous syndrome
lipodermoids (or dermolipomas), Complex choristomas
6
Goldenhar syndrome name
oculoauriculovertebral dysgenesis
7
Treatment for PAM
excision with cryotherapy
8
Lesar-Trelat sign
sudden onset of numerous seborrheic keratoses --> work-up for gastrointestinal adenocarcinoma
9
PAM - uni or bi, in whom
uni, light-colored, middle-age
10
PAM - % progress to conj melanoma
30-50%
11
PAM - location suspicious for atypia
palpebral, fornix, plica, caruncule
12
Benign melanosis - where
perilimbal conj, may extend onto the peripheral cornea ("striate melanokeratosis")
13
Nevus of Ota
oculodermal melanocytosis
14
Risk of melanoma in Risk of melanoma in ocular or oculodermal melanocytosis
1/400
15
Risk of glaucoma in ocular or oculodermal melanocytosis
10%
16
% of conj melanoma arise from PAM
70%
17
Factors with risk of PAM progression
more than 3 hour clocks of pigmentation, caruncule, fornix, palpebral
18
Conj melanoma - recurrence rate
50%
19
Origin of conj melanoma
70% PAM, 25% de novo, 5% nevus
20
Melanoma - poor prognosis
palpebral, fornix, caruncule, eyelid margin. tchickness >1.8mm, pagetoid, full-thickness intraepithelial spread, lymphatic invasion, mixed cell type, de novo, not limbus, residual involvement at the surgical margin
21
Margin in excision of nevus
2mm
22
Reddish brown nodule on the surface on the caruncule
onkocytoma
23
slow-growing cystadenoma
onkocytoma
24
onkocytoma cystadenoma - origin
ductal and acinar cells of main and accessory lacrimal glands
25
Treatment of CIN
excision with 3-4 mm margins and cryotherapy, topical IF2b, MMC, 5-FU
26