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Flashcards in Epilepsy Deck (11):
1

How many epileptic seizures are required to diagnose epilepsy? Time period.

2 seizures more than 24 hours apart.

2

Causes of epilepsy

1/3 idiopathic (familial)
2/3 anatomical/structural cause

3

Precipitating factor for seizure

inadequate sleep
alcohol abuse/withdrawal
medications- tricyclic antidepressants, cocaine
trauma, stroke, haemorrhage, raised ICP
Infection (meningitis, encephalitis, HIV

4

Medications for
a) focal seizure

carbamazepine and lamotigine

5

b) Tonic-Clonic

Sodium Valporate
Lamotrigine

6

c) Myoclonic

Sodium Valporate

7

d) Absent

Sodium Valporate
Lamotrigine
ethosuximide

8

Info to tell patient

Driving:
1) first seizure: 6 months
2) epilepsy: 1 yr

Warning dangerous: swimming, heights

9

Which drugs is contraindicated on hx of bone marrow suppression, AV node conduction abnormality and acute porphyria

carbamazepine

10

What must you tell women starting anti-epileptics

increased risk of teratogenicity, want to stop to fall pregnanct- need specialist

11

Which anti epileptics work by effecting GABA

Carbamazepine: ↑GABA transmission and block Na+ channels

SV: ↑GABA conc & blocks Na+ channels