Epilepsy and AEDS Flashcards

1
Q

epilepsy

A

recurrent seizures caused by disturbance of neuronal activity in brain
repetitive firing of action potentials, may lead to motor convulsions

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2
Q

seizure

A

abnormal electrical discharge of brain neurons
alteration of behavior and motor
possible impairment, loss of conscious, muscle twitch/convulsion

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3
Q

convulsion

A

involuntary contraction/spasm of voluntary muscle

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4
Q

EEG (electroencephalogram-diagnostic tool)

A

records electrical activity of brain

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5
Q

possible causes of seizures

A

hypoxia, meningitis, fever, head injury, brain tumor, genetics, emotional stress, hypoglycemia, birth defects, drugs

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6
Q

types of epilepsy

A

generalized seizures

partial seizures

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7
Q

generalized seizure

A

involves both hemispheres of brain

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8
Q

partial seizure

A

specific area of brain but may spread and become generalized

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9
Q

types of generalized seizures

A

gran mal/tonic-clonic
myoclonic
atonic
petit mal/absence

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10
Q

gran mal/tonic-clonic seizures

A

aura precedes seizure, loss of consciousness, increase in BP and HR, may urinate/deficate self, may bite tongue, may last several minutes

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11
Q

tonic convulsions

A

stiff, tense, rigid

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12
Q

clonic convulsions

A

spasms with rigidity and relaxation alternating rapidly

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13
Q

status epilepticus

A

series of grand mal seizures without cessation (medical emergency)
can lead to brain damage and death

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14
Q

drug of choice for status epilepticus

A

IV diazepam (VALIUM®) or IV lorazepam (Ativan®)

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15
Q

myoclonic seizures

A

muscle contractions, brief, one part of body affected, may spread to other parts

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16
Q

atonic seizures

A

loss of muscle tone, usually results in a fall

17
Q

petit mal/absence seizures

A

no aura, brief impairment of consciousness/cloudy memory, staring/rapid blinking, lasts few seconds to a minute

18
Q

signs of an aura

A

nausea, odor, visual disturbances/floaters, numbness, dizziness/tingling

19
Q

types of partial seizures

A

simple and complex

20
Q

simple partial seizures

A

sensory or motor, muscle twitching, limited area of brain, brief, no loss of consciousness

21
Q

complex partial/psychmotor seizures

A

loss of consciousness, bizarre/purposeless movements, no memory of seizure, several parts of body, can lead to tonic-clonic

22
Q

complex partial/psychmotor seizures

A

loss of consciousness, bizarre/purposeless movements, no memory of seizure, several parts of body, can lead to tonic-clonic

23
Q

antiepileptics

A

prevent/reduce occurrence and severity of seizures by decreasing excitability of brain cells
usually given orally

24
Q

anticonvulsants

A

stop convulsive seizures, produces sedation

usually IM or IV

25
drug classifications to treat epilepsy
barbiturates hydantoins benzodiazepines miscellaneous
26
MOA of barbiturates
increase inhibitory effects of GABA, suppress neuronal excitability
27
pt teaching/ SE of barbiturates
sedation, dizziness, rash, N/V, do not abruptly stop
28
MOA of hydantoins
prolong inactivation period of sodium channels, decrease hyper excitability and rapid firing action potentials
29
what do all hydrantoin drugs end in
toin
30
pt teaching/SE of hydantoins
thrombocytopenia, anemia, arrhythmias, lupus, gingival hyperplasia- encourage good dental hygiene
31
MOA of benzodiazepines
increase inhibitory affects of GABA
32
pt teaching of benzodiazepines
sedation, monitor for dependance (controlled substance), ability to operate a vehicle may be impaired
33
what do all benzodiazepines end in
pam or lam
34
MOA of most miscellaneous AED
block GABA inhibit calcium channles inhibit rapid firing of neurons
35
safety meausres with AEDs
do not stop abruptly 3 month without seizure and meds before driving service dog/medical alert bracelet
36
what to do in event of seizure
assist to floor, clear surrondings, do not restrain, provide cushioning, seek medial assistance
37
uses for AEDs
seizures, sedation, mental health, migraines, neuromuscular injury