Epinephrine ( 1:10,000 and 1:000 )

Question 1

Brand Name

Epinephrine

Answer 1

Adrenalin

Question 2

Drug Class

Epinephrine

Answer 2

Sympathomimetic

Question 3

Indications

Epinephrine

Answer 3

Cardiac Arrest

Symptomatic Bradycardia refractory to atropine and pacing

Severe Hypotension secondary to Bradycardia and pacing

Allergic Reaction

Anaphylaxis

Asthma

Question 4

Mechanism of Action

Epinephrine

Answer 4

Alpha & Beta Antagonist (some Alpha more Beta)

Beta 1: Inotropic, Chronotropic, Domotropic

Beta 2: Bronchial smooth muscle relaxation

Question 5

Contraindications

Epinephrine

Answer 5

Hypertension
Hypothermia
Pulmonary Edema
Myocardial Ischemia
Hypovolemic Shock

Question 6

Adverse Effects

Epinephrine

Answer 6

Nervousness
Restlessness
Headache
Tremor
Pulmonary Edema
Dysrhythmias
Chest Pain
Hypertension
Tachycardia
N/V
Anxiety

Question 7

Precautions

Epinephrine

Answer 7

Inactivated by exposure to sunlight and alkaline solutions

MAIO’s may potentiate effects

Beta blockers will blunt effects

Question 8

Dose

Epinephrine

Answer 8

Adult
Allergic Reaction: 0.3 - 0.5 mg (IM/SC) 1:1,000
Asthma : 0.3 - 0.5 mg (IM/SC) 1:1,000
Cardiac Arrest: 1 mg (IV/IO) 1:10,000 q 3-5 mins
Bradycardia: 2 - 10 micro-grams/min infusion

Pedi
Allergic Reaction: 0.01 mg/kg (IM/SC) 1:1,000 *max 0.3 mg
Cardiac Arrest: 0.01 mg/kg 1:10,000 q 3-5 mins *max single dose 1 mg