epithelia Flashcards

(52 cards)

1
Q

what are the 4 basic tissue types of organs

A

epithelium
connective tissue
muscle
nervous tissue

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2
Q

what are epithelia composed of

A

closely aggregated, polyhedral epithelial cells with a minimum of intercellular substance

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3
Q

adhesion between epithelial cells is
A. strong
B. weak

A

A. strong

thus cellular sheets are formed which are able to cover exposed external surfaces and line internal cavities

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4
Q

what does the epithelial form

A

the outer protective layer of the skin

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5
Q

epithelia are usually polarized

A

yes

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6
Q

all epithelial cells have a sheet like structure composed of extracellular matrix components called what

A

basal lamina (basement membrane)

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7
Q

epithelial cells are described as non vascular, what does this mean

A

nutrients from capillaries in underlying tissue must diffuse across the basal lamina

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8
Q

epithelial cells tend to bind together in what form

A

sheets

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9
Q

what are some functions of the epithelia

A
mechanical barrier (skin)
chemical barrier (lining of stomach)
absorption (lining of intestine)
secretion (salivary gland)
containment (lining of urinary bladder)
locomotion (by cilia - oviduct)
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10
Q

the role ofthe epithelium determines its what

A

type and structure

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11
Q

two types of cellular components that are vital to the function of epithelia in the care

A
  • cytoskeleton (maintains cellular integrity)

- intercellular junctions(links cells together into a functional unit)

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12
Q

what are the three main classes of filaments that form the cytoskeleton of cells

A

microfilaments
intermediate filaments
microtubules

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13
Q

what is the diameter of the microfilament

A

5nm

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14
Q

what is the diameter of the intermediate filament

A

10nm

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15
Q

what is the diameter of microtubules

A

25

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16
Q

how do filaments become attached to cell membranes and to each other and what does this form

A

by anchoring and joining proteins to form a dynamic 3 - dimensional internal scaffolding in the cell

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17
Q

the fine strands of what protein make up microfilaments

A

actin

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18
Q

what are the functions of microfilaments

A

anchorage, movement and extension of cell membrane

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19
Q

under which structural feature are actin filaments located

A

cell membrane

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20
Q

in microfilaments, what does globular actin polymerize to form

A

filamentous actin

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21
Q

what do intermediate filaments bind together

A

bind intracellular elements and then binds this to the plasmalemma

22
Q

intermediate filaments are not as dynamic as what

A

microfilaments and microtubules

23
Q

what two subunits are microtubules composed of

A

alpha and beta in an alternating array

24
Q

microtubules can be described as

A

assembled and disassembled

25
what are microtubules important in
movements of components in the cell and in cell division (from the spindle apparatus)
26
intercellular junctions are specialised structures which link what
individual cells together into a functional unit
27
what are the 3 types of intercellular junctions
occluding junctions anchoring junctions communicating junctions
28
what's the role of an occluding junction
links cells to form a diffusion barrier
29
what's the role of an anchoring junction
provides mechanical strength
30
what's the role of a communicating junction
allows movement of molecules between cells
31
what effect does an occluding junction have on diffusion
it inhibits diffusion
32
occluding junctions appear as a focal region of close apposition between what
adjacent cell membranes
33
in occluding junctions, what is another name for a tight junction
zonula occludens
34
in an anchoring junction, what is the role of an adherent junction
links submembrane actin bundles of adjacent cells
35
what is another name for adherent junctions
zonula adherens
36
what transmembrane molecule bind to eachother in the extracellular space, and, through link molecules, to actin of the cytoskeleton
cadherin
37
what do desmosomes link and what is the name of the function
links submembrane intermediate filaments of adjacent cells | called macula adherens
38
what role do desmosomes provide in the skin
provide mechanical stability
39
what do communicatice junctions allow
selective diffusion of small molecules and ions between adjacent cells
40
where are communicative junctions found
epithelia smooth muscle cardiac muscle
41
what is a junctional complex
close association of several types of junctions found in certain epithelial tissues
42
covering epithelia are based on what
cell shape the number of layers of cells cell surface, tissue surface, specializations presence of any specialized cell types
43
``` if a cell were to be described as A. squamous B. cuboidal C. columnar, what would this be describing ```
A. flattened, like a fish scale B. cube shaped C. like a column, tall and thin
44
``` if a cell were to be described as A. simple B. stratified C. pseudostratified, what would this be describing ```
A. one layer B. two or more layers C. tissue appears to have multiple layers, but in fact all cells are in contact with the basal lamina
45
what are some specializations of cell surface or tissue surface
- prominent microvilli - cilia - kertinized (presence of layers of keratin proteins on the tissue surface)
46
what are goblet cells
single cell mucous glands
47
what is the role of microvili in epithelia
serves to increase the surface area of the cell membrane
48
what are the length of microvili
0.5-1um
49
how long are motile cells
10um long
50
what is the purpose of motile cells
serve to propel mucous or fluid over the cell surface
51
what structures can be seen within cilia
core of microtubules
52
what are keratins
groups of tough structural proteins