ERROR IN MORPHOGENESIS

Question 1

WHAT ARE THE INTRINSIC ERRORS

Answer 1

FAILURE OF EMBRYO TO DEVELOP
AGENESIS, APLASIA, HYPOPLASI, MALFORMATION

Question 2

WHAT ARE THE EXTRINSIC ERRORS

Answer 2

EXTERNAL FORCE IMPACTS NORMAL DEVELOPMENT
DISRUPTION, DEFORMATION

Question 3

EXPLAIN WHAT AGENESIS IS

Answer 3

MISSING ORGAN CAUSED BY MISSING EMBRYONIC TISSUE. EG RENAL AGENESIS

Question 4

EXPLAIN WHAT APLASIA IS

Answer 4

MISSING ORGAN DUE TO GROWTH FAILURE EMBRYONIC TISSUE
EG. THYMIC APLASIA (DIGEORGE SYNDROME)

Question 5

HYPOPLASIA

Answer 5

INCOMPLETE ORGAN DEVELOPMENT
EG MICROCEPHALY
IT IS NOT THAT THE EMBRYONIC TISSUE WAS NOT PRESENT, IT IS NOT THAT FAILED TO GROW, IT IS JUST THAT IT DID NOT GROW COMPLETELY.

Question 6

MALFORMATION

Answer 6

ABNORMAL DEVELOPMENT OF STRUCTURE
NEURAL TUBE DEFECTS
CLEFT LIP OR PALATE
CONGENITAL HEART DEFECTS

Question 7

EXPLAIN WHAT DISRUPTION IS

Answer 7

EXTRINSIC ERROR
NORMAL TISSUE GROWTH ARRESTED DUE TO EXTERNAL FORCE
EG AMNIOTIC BAND SYNDROME - FETAL STRUCTURES ENTAPPED BY FIBROUS BANDS IN UTERO -
OFTEN INVOLVES LIMBS OR DIGITS

Question 8

DEFORMATION

Answer 8

EXTERNAL FORCE LEADS TO ABNORMAL GROTH - NOT ARREST -
DEFORMS OR MISSHAPES STRUCTURE
CLASSIC EXAMPLE POTTER/S SYNDROME