Esclerose Sistêmica Flashcards

1
Q

Qual dos autoanticorpos da ES se associa a pior prognóstico e por que?

A

Anti-Scl 70. Anti-Scl-70 antibody presence is associated with a high risk of early interstitial lung disease, scleroderma renal crisis, and cardiac involvement.

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2
Q

Na ES, anti-U1-RNP se associa a:

A

Síndrome de sobreposição

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3
Q

Na ES: antifibrilarina ou anti-U3-RNP se associa a

A

ES forma difusa e HP.

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4
Q

Na ES, anticentrômero é específico?

A

Não! Ocorre em 50 a 80% dos pacientes, mas também ocorre no LES, SSj e CBP

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5
Q

Na ES, antiRNA polimerase III aumenta o risco de:

A

Maior envolvimento cutâneo

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6
Q

Na ES, anti-RNA polimerase I:

A

Maior envolvimento cardíaco e renal

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