Estrin Sertoli Pyometra

Question 1

Most common causes of hyperestrinism in dog

Answer 1

Cystic ovaries
Granulosa cell tumors
Sertoli cell tumors
Exogenous Rx

Question 2

S/S of hyperestrinism

Answer 2

Vulvar edema +/- discharge
Alopecia caudal trunk of perineum
Epidermal hyperpigmentation
Nipple enlargement
Attractive to other dogs

Question 3

What is estrogen myelotoxicosis?

Answer 3

Sequella to hyperestrogenism. Causes anemia, leukopenia, and thrombocytopenia.

Question 4

Tx of hyperestrinism

Answer 4

OVH for cystic ovaries.

Can give neupogen and epogen for estrogen myelotoxicosis.

Question 5

What are the 3 types of testicular tumors?

Answer 5

Sertoli - can metastasize and feminize.
Seminoma - can metastasize and feminize.
Interstitial/Leydig - mets rare, feminize rare.

Question 6

Sertoli cell neoplasia incidence

Answer 6

Age range 3-20y old (8-9)

Dogs with extrascrotal involvement with feminization may present at a younger age than dogs with scrotal involvement.

Question 7

S/S of sertoli cell tumor

Answer 7

Testicular enlargement
Feminization
-16.7% w/ scrotal SCT
-50% w/ inguinal SCT
-70.4% w/ abdominal SCT

Question 8

Feminization s/s

Answer 8

• atrophy of contralateral testicle
• symmetrical alopecia
• gynecomastia
• pendulous prepuce
• prostatic changes, metaplasia/infection
• tendency to attract other males
• depressed libido
• lethagy

Question 9

Pyometra etiology

Answer 9

Hormonally influenced - progesterone.

Several drugs predispose - megestrol acetate

Question 10

S/S pyometra

Answer 10

Onset of symptoms 4-12 weeks post estrus.
PU/PD
Vaginal discharge present in only 50-60%
Anorexia
Depression
Abdominal distention
Temp variable
CATS MORE SUBTLE

Question 11

Systemic effects of pyo-

Answer 11

anemia
cardiac arrhythmias
impaired renal function
sepsis
toxemia

Question 12

Tx of pyo-

Answer 12

IV fluids
ABs that cover gram - bacteria
OVH
MEDICAL ALTERNATIVE - NOT IDEAL….IV fluids, ABs, PGF2a for breeding small animals