Eukaryotic Cells Flashcards

1
Q

Relative average size

A

10 - 100 micrometers

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2
Q

What marks the golgi

A

alpha mannosidase II

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3
Q

What marks the nucleus

A

DNA

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4
Q

What marks the ribosomes

A

rRNA

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5
Q

What marks the endosome

A

uptake of peroxidase

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6
Q

What marks the cytosol

A

L-lactate dehydrogenase

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7
Q

What marks the peroxisome

A

Catalase

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8
Q

What marks the mitochondrion

A

Succinate dehydrogenase and cytochrome c-oxidase

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9
Q

What marks the ER

A

Catalase

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10
Q

KDEL sequence location

A

C terminal end of protein

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11
Q

KDEL sequence function

A

Prevents protein secretion inthe ER, proteins can only leave once sequence has been cleaved

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12
Q

Rough ER Functions

A

Synthesis of secretory proteins, glysolation

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13
Q

Glycosylation

A

Addition of N-linked oligosaccharides to peptides

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14
Q

What is N-linked

A

Binds to N-terminus of amino acid

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15
Q

Where is the rough ER found in high conc. in

A

Neurons in Nissl bodies, pancreatic acinar cells, chief cells of stomach

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16
Q

What marks the lysosome

A

Beta N- acetylhexoaminidase and beta galactosidase

17
Q

What marks the plasma membrane

A

Na+/K+ ATPase and phosphodiesterase I

18
Q

What is a nissl body

A

Subcellular component of a dendrite

19
Q

What do chief cells produce

A

Pepsinogen

20
Q

Functions of smooth ER

A

Steroid synthesis, Ca 2+ storage in sarcoplasmic reticulum, hepatocyte detoxification, produces peroxisomes, carbohydrate metabolism, lipid metabolism

21
Q

How does the smooth ER detoxify hepatocytes

A

Hydroxylation - cytochrome P450 hydroxylase complex and Conjugation - attachment of polar moiety to toxins

22
Q

Where is steroid synthesis abundant

A

Testes, ovaries, adrenal cortex, corpus luteum

23
Q

What is gluconeogenesis mediated by

A

Glucose-6-phosphatase

24
Q

What is SERCA and what is its function

A

sarco/ER Ca2+/ATPase, transports Ca2+ from cytosol into smooth ER

25
Q

Function of Ca2+ release

A

Mediates/initiates muscle contraction

26
Q

What is the purpose of conjugation

A

Makes toxins more water soluble, part of detoxification process