Evidence for striatal dopamine release induced by administration of Δ9-tetrahydrocannabinol (THC): selectivity to limbic striatum (Bossong, et al., 2015)

Question 1

This research has evidenced direct THC activation in the limbus striatum causing elevated dopamine function

Answer 1

This research has evidenced direct THC activation in the limbus striatum causing elevated dopamine function

Question 2

Patients with psychosis show increases in subcritical synaptic dopamine content, and abnormally high dopamine release after amphetamine treatment (Kesha, et al 2018)

Answer 2

Patients with psychosis show increases in subcritical synaptic dopamine content, and abnormally high dopamine release after amphetamine treatment (Kesha, et al 2018)

Question 3

Hence, vulnerability/ high sensitive dopamine systems will be exacerbated by THCs action in the limbus striatum and partially continue to the development of positive symptoms (Kesby et al 2018)

Answer 3

Hence, vulnerability/ high sensitive dopamine systems will be exacerbated by THCs action in the limbus striatum and partially continue to the development of positive symptoms (Kesby et al 2018)