evolution Flashcards

1
Q

Why are viruses sometimes considered to be “alive”?

A

they can reproduce and mutate/evolve

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2
Q

Why viral infections are usually difficult to treat with drugs.

A

no clear target for drug - virus in host and uses its resources. unaffected by antibiotics & other treatment methods used for bacteria.

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3
Q

hypotheses for the evolutionary origin of viruses.

A

evolved from cells since they require host cell to reproduce. they evolved into one which uses directions to reproduce etc.

ancient/before cells: from “primordial gene pool” - rna said to be first genetic material.

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4
Q

Why the effectiveness of anti-viral drugs is likely to decrease over time

A

viruses mutate/evolve quickly as their lifespans are short. drugs will soon encounter viruses that are resistant

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5
Q

Principles underlying evolution by natural selection:

A

heritable variation, non-random reproduction or survival, change in genotype of the population

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6
Q

What is heritable variation and how does it relate to natural selection?

A

it is the variation of what is passed from parent to offspring. helps natural selection alter frequency of alleles in the gene pool.

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7
Q

Rationale for using multiple drugs simultaneously to treat viral infections

A

it will take more nucleotides for a virus to develop resistance. viruses are unlikely to develop resistance to all the drugs.

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8
Q

Evolutionary origins of HIV and how does this show that eradicating viral diseases is difficult?

A

from virus that infected primates - chimpanzee. the virus evolved allowing it to spillover between both species (at least 5 times!!). It constantly evolves.

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9
Q

what is “scala natura” thinking.

A

aristotle’s ladder-classification system. non-living at bottom, humans and god at top. his system merged with biblical account of creation. organisms created by god and never change/go extinct. no new species.

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10
Q

Why is scala natura not compatible with modern evolutionary theory

A

modern evolutionary theory believes species can evolve while scala natura goes against this.

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11
Q

What evidence supports the idea of descent with modification from a common ancestor

A

geology and the fossil record, the geographic distribution of species, and comparative morphology

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12
Q

how does geology and fossil records support the idea of descent with modification from a common ancestor.

A

fossils found were similar to current species, but not the same. earth’s moving plates convinced Darwin that life can change as well.

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13
Q

how does geographic distribution of species that support the idea of descent with modification from a common ancestor.

A

species similar to each other were found in diff parts of the earth. species on an island would be similar to mainland species. Darwin thought that after being separated both species changed over time.

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14
Q

how does comparative morphology support the idea of descent with modification from a common ancestor.

A

species had similar bone structures which server diff purposes. some animals had structures that were now of no use (vestigial) but were similar to other species’.

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15
Q

Give examples of homologous traits (comparative)

A

human arm, bat wing, and seal flipper. pelvis of human, dog, and cat. tailbone of monkey and human.

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16
Q

How has our understanding of evolution has changed since Darwin’s time

A

idea of genes/alleles and how they’re passed thru generations was introduced. concept of mutations as well.

17
Q

why mutations are important to evolution

A

allows for diff traits to rise. it is the source of variation which is a major part of natural selection. it does NOT determine the path of evolution but randomly introduces alleles which may allow them to survive.

18
Q

debunking misconceptions about evolution and natural selection

A

they are not the same. natural selection is a factor of evolution.

evolution is not always slow. refer to virus & bacteria which evolve pre quickly.

natural selection is based off phenotypes not genotypes.

humans are still evolving!!!

19
Q

Characteristics of a scientific theory

A

set of testable hypotheses that attempt to explain facts bout natural world. is falsifiable!! a scientific theory needs to be open to possibilities of it being wrong.

20
Q

difference between falsifiable and non-falsifiable statements

A

a falsifiable theory needs one observation to disprove it while a non-falsifiable theory needs extensive research.

21
Q

Darwin’s contributions to the theory of evolution.

A

he did not make the theory of evolution but did prove natural selection (“descent with modification from a common ancestor”) which helps explain it.

his observations: variation for traits in population; those with favored traits are more likely to survive and leave more off springs who inherit these traits; over time those with favored traits become the majority (adaptation)

22
Q

What is variational rather than transformational?

A

evolution is variational. acquired traits are not passed down.

23
Q

What is gradualism?

A

takes many generations to produce large evolutionary changes

24
Q

What is speciation?

A

it is when species diverge from parent species. they can no longer reproduce with them. generally due to geological separation.

25
Q

why are viruses non living?

A

they cant reproduce without using a host’s resources - they lack a metabolic system so they use host’s energy.

they are not a cell (no cytoplasm enclosed by plasma membrane).

nucleic acid genome can be rna/dna (contains their genetic material).

26
Q

similarities and differences between cells and viruses

A

both have nucleic acid genomes and can evolve.

but cells produce their own energy, undergo mitosis, have organelles, and membrane (VIRUSES DONT HAVE MEMBRANE!!!!)

27
Q

what does the AZT target and why?

A

it targets the reverse transcriptase due to its high mutation rate

28
Q

what is the general process of HIV infecting a cell?

A

attachment, entrance into host cell via endocytosis, RNA secreted into host and RT catalyzes the synthesis from RNA to DNA, integration into host cell, RNA is produced and can serve as the genome to be translated to produce new viral proteins, complete HIV particles will assemble