Ex. 28 Endocrine System pt Flashcards
(25 cards)
Difference between endocrine and exocrine glands?
Endocrine glands release hormones right into the blood stream. Example: Thyroid and parathyroid. Exocrine glands secrete their substances through a duct into a lumen or onto a surface. Example: sweat gland, oil gland, mammory glands.
What is a hormone and describe what it acts on?
A hormone is a chemical messenger that is secreted by endocrine glands into the blood and acts on target cells, target tissues, or target organs.
Pineal gland does what?
produces melatonin. Its function is to regulate our sleep cycle (circadian rhythm).
Hypothalamus:
Controls hormone release by secreting stimulating and or inhibiting hormones
-Non endocrine functions include: body temperature, sleep/awake, hunger thirst, memory, blood pressure, heart rate
What 2 organs are considered the control center of the endocrine system - all other endocrine organs?
Pituitary gland and hypothalamus
Pituitary gland?
- hypophysis
- connected to the hypothalamus by the infundibulum
- two lobes: adenohypophysis (anterior lobe)
neurohypophysis (posterior lobe)
Adenohypophysis?
anterior lobe of pituitary gland
- composed of endocrine tissue (simple cuboidal)
Neurohypophysis?
posterior lobe of pituitary gland
- composed of nervous tissue
- hormones are produced in the hypothalamus and transported to the neurohypophysis
- it stres and releases the hormones, while the anterior produces?
Thyroid gland?
- produces T3 and T4
- T3 and T4 set your metabolic rate
- Produces calcitonin, which decreases blood calcium by depositing it in bone.
Thyroid gland appearance?
Thyroid is composed of follicle and parafollicular cells. Follicle is the entire thing. Follicular cells are the boarder cells. The inside of the follicle is the colloid. Parafollicular cells are between the follicles.
Parathyroid glands?
usually 4 glands
- on posterior of thyroid gland
- produce parathyroid hormone, which increases blood calcium by getting calcium from bones.
Thymus?
- “shrinking” gland
- produces thymosins, which is a big group of hormones
- Its very important for your immune system because it is where your T cells (of WBC’s) mature at.
- By 60 or 70, the thymus is replaced by scar tissue
Pancreas?
- Has endocrine and exocrine functions
- endocrine: pancreatic islets produce insule and glucagon
- exocrine: acinar cells produce pancreatic juice (enzymes) for digestion. It secrets through a duct.
- pancreatic islet’s are lighter and less dense, while acinar cells stain darker
Pancreas hormones?
insulin - lowers blood glucose
glucagon - increase blood glucose
Adrenal glands structure?
cortex - external
medulla - internal
Adrenal gland cortex?
cortex produces corticosteroid hormones.
Function of corticosteroid hormones is water and electrolyte balance; metabolism, also produces sex hormones (androgens and estrogens).
Adrenal gland medulla?
medulla produces epinephrine and norepinephrine. Function is fight or flight. - increased heart rate - pupil dialation - slows down digestion - increases blood flow to muscles - dialate airways - increase respiration
Ovaries?
have endocrine and exocrine functions.
follicles contain:
- granulosa cells: produce estrogen (and progesterone)
- Oocyte (aka. Egg)
Progesterone is released when egg is released
Blood characteristics?
- connective tissue
- pH = 7.35 to 7.45
- Two basic components
1. Plasma (55%)
2. Formed elements (45%) - mostly RBC’s
About blood plasma?
Over 90% water
Function of plasma: transport
Transports all of these below:
- proteins
* Albumin (most abundant)- Albumin is a transporter protein, acts as a buffer to resist pH change in blood. helps draw fluid back from tissue via colloid osmotic pressure
* Globulin (second most abundant) - Globulin is a transporter protein, specific class of globulins that are your antibodies.
* Fibrinogen (not much. like 4%) - eventually becomes fibrin when blood needs to from a clot. precursor to fibrin, which is sticky.
Misc: electrolytes, hormones, gases, nutrients, wastes
How many formed elements are there?
3: Erythrocytes (RBC), Thrombocytes (platelets), Leukocytes (WBC)
Erythrocytes:
- Contain hemoglobin, which transports oxygen
- Size: -7.5 um (smallest cell)
- Shape: biconcave disk - Gives them more surface area and makes them more flexible
- Average count: 4.2 - 6.2 million/uL
Does a mature RBC have a nucleus?
no, it does as its maturing, but at some point it pushes the nucleus out and makes room for more hemoglobin. As a result they don’t live as long
Thrombocytes:
Platelets
- they clot the blood
- Platelets are considered cell fragments. One platelet is not considered a cell.
- These fragments secret hormones, secrete chemicals that cause vasoconstriction, help convert fibrinogen to fibrin.