Exam 1

Question 1

Select all that are true regarding the body’s fluid compartments.
A) there is a higher concentration of protein in the blood plasma than in the intracellular fluid
B) the osmolarity of the interstitial fluid is higher than the intracellular fluid.
C) sodium concentration is lower in the intracellular fluid than in the blood plasma
D) trans cellular fluid (like synovial fluid) is considered part of the intracellular fluid
E) potassium is more concentrated in the intracellular fluid than the blood plasma

Answer 1

C and E (cell physiology slide 11)

Question 2

Fill in the blank: there is ______ exchange between the ECF and ICF, and there is ______ exchange of water and small solutes between the interstitial fluid and the plasma.

Answer 2

Regulated, free (cell physiology slide 12)

Question 3

The lipid bilayer of the cell membrane is NOT:
A) composed of amphipathic molecules
B) freely permeable to gas molecules and small charged molecules
C) selectively permeable
D) capable of self-healing
E) actively involved in cell signaling

Answer 3

B. The lipid bilayer is freely permeable to gas molecules and small UNcharged molecules. Large or charged molecules need assistance (cell physiology slide 15, 16, 19).

Question 4

Match the protein to its description:
1) Channel
2) Carrier
3) Cell Recognition
4) Receptor
5) Enzymatic
6) Linkers and Structural

A) directly carry out metabolic reaction
B) help hold cell to other cell or matrix; scaffolding for cytoskeleton
C) combine with substance to allow its passage
D) the cell’s chemical ID, body can use these to recognize foreign cell
E) after binding with messenger molecule, causes cellular response
F) tubular, allow molecules to pass

Answer 4

1F
2C
3D
4E
5A
6B
(cell physiology slide 21)

Question 5

True of False: The lipids of the cell’s inner and outer monolayers are interchangeable.

Answer 5

False (cell physiology slide 16)

Question 6

Select the three major classes of membrane lipid molecules:
a) lignin
b) phospholipids
c) cholesterols
d) glycolipids
e) lipohormones

Answer 6

b, c, d
(cell physiology slide 22)
I hope lipohormones aren’t actually a thing

Question 7

____ is an organized meshwork of polysaccharides and proteins secreted by fibroblasts

A) The extracellular matrix
B) The cytoskeleton
C) The folding of the cell membrane
D) The fluid mosaic model
E) The cell wall

Answer 7

A (cell physiology slide 25)

Question 8

By way transmembrane glycoproteins called integrins, actin filaments of the cell attach to which of the following parts of the extracellular matrix? (Select all that apply)
A) fibronectin
B) proteoglycan
C) elastin
D) laminin
E) glycosaminoglycans

Answer 8

A & D (cell physiology slide 25)

Question 9

Diseases like cancer, fibrosis, arthritis, and atherosclerosis are all associated with which of the following?
A) degradation of cell recognition proteins
B) ion channel disfunction
C) changes in the extracellular matrix
D) pH change in lysosomes

Answer 9

C (cell physiology slide 25)

Question 10

The glycocalyx is crucial in which of the following? (Select all that apply)
A) sorting embryonic cells into tissues and organs
B) allowing for freedom of movement through the extracellular space
C) rejecting foreign cells by the immune system
D) protecting the cell from mechanical and chemical damage

Answer 10

A, C, D (cell physiology slide 26)

Question 11

Fill in the blank: The cell contains a ____ which is an RNA-containing dense body that synthesizes ribosomal RNA

Answer 11

nucleolus (cell physiology slide 27)

Question 12

T or F: The Rough ER is involved with various synthesis processes, detoxification and storage

Answer 12

F (it’s the Smooth ER) (cell physiology slide 30)

Question 13

T or F: The sarcoplasmic reticulum is a modified smooth endoplasmic reticulum, sequestering Ca ions.

Answer 13

T (cell physiology slide 30)

Question 14

Which of the following consists of flattened, curved saccules, tags proteins for specific function, and maintains the plasma membrane?
A) Rough ER
B) Smooth ER
C) Sarcoplasmic Reticulum
D) Golgi apparatus

Answer 14

D (cell physiology slide 31)

Question 15

Your patient presents with mental retardation and blindness. He is diagnosed with Tay-Sachs disease. You know this is a related to
A) malformation of the Golgi apparatus
B) lysosomal storage disease
C) error in peptide bond formation
D)overproduction of peroxisomes

Answer 15

B

Question 16

Select all membrane-bound organelles
A) ribosome
B) peroxisome
C) lysosome
D) proteasome
E) centriole

Answer 16

B C (cell physiology slide 28, 31, 33, 35)

Question 17

Proteins that are destined for destruction are tagged with _____, an amino acid peptide that directs the protein to the proteasome.
A) proteatin
B) ubiquitin
C) calcitonin
D) tachykinin
E) Isopeptag

Answer 17

B (cell physiology slide 35)

Question 18

The goal of cystic fibrosis drugs is to add a signal molecule to certain malformed channel proteins so that they appear normal. Otherwise, the channel proteins would be destroyed by a ______.

Answer 18

proteasome (cell physiology slide 35)

Question 19

The most abundant structures of the cytoskeleton are _______ and are involved in cell stability.
A) microfilaments
B) intermediate filaments
C) microtubules

Answer 19

B (cell physiology slide 36)

Question 20

______ are part of the cytoskeleton and are involved in movement of the cell as well as constant assembly/disassembly.
A) Microfilaments
B) Intermediate filaments
C) Microtubules

Answer 20

C (cell physiology slide 36)