Exam 1 Flashcards
Types of seizures
-Simple w/o impairment of consciousness
-Complex impairment of consciousness
-secondary generalized partial that evolves
change in seizure type
tumors
what is status epilepticus
No recovery in between seizures
Ration poly therapy agents
-want different moas w/ lower doses in refractory patients
-Topiramate or Levetiracetam
Which antiepi in pregnancy
-phenobarbital, oxcarbamazepine, lamotrigene, euthosuximide, folic acid
which antiep CI in pregancy
Phenytoin and Sodium Valporate
Which antiepi dec effectiveness of oral contraceptives
-enzyme inducing : carbamazepine, lamotrigene, phenytoin, phenobarbital
Which antiepi inh ca channels
-Ethosuximide, valproate, trimethiadone, Levetriacetam
Which antiepi inh GABA
Phenobarbital, benzos, valporate, tigabine
Phenytoin SE/AE
- GI
- fetal hydratoin syndrome
- hirutism
- anemia
-gingival hyperplasia
Carbamazepine clinical pearls
-intense monitoring for blood dyscrasis
-if wbc drop and dont return to norm a/f 1 mon D/C
-if rbc drop D/C (FATAL aplasia anemia)
Valproate SE
- GI
- Weight gain
- Aleopcia
- Neural tube defects
- hepatotoxicity
Lamotrigene clinical pearl
- ask about rash (AE: SJS) titrate slowly
Topiramate AES
-Dose dep: aphasia, bilateral parastesis, dec weight
-Preventable w/ hydration: blindness, kidney stone
Levetiracetam pearls
- safe and effective
-cns depressant no alcohol
